Alena V. Savenka
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Also affiliated: United States Food and Drug Administration (2024–2026); University of Arkansas Medical Center (2020); Central Arkansas Veterans Healthcare System (2011–2021)
Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Alena V. Savenka's research program focuses on understanding the mechanisms of cellular injury and the development of potential therapeutic interventions. Her work has investigated the effects of various compounds, including gamma-tocotrienol, on radiation-induced intestinal injury in nonhuman primate models. Savenka has also explored the antimicrobial properties of novel chemical derivatives against Gram-positive bacteria and examined the potential of repurposed vaccines for cancer immunotherapy. Her publications include studies on DNA fragmentation and apoptosis as indicators of kidney injury, as well as proteomic insights into bacterial biofilm formation. Savenka has an h-index of 13 with 37 total publications and 633 citations, and has collaborated with researchers from the University of Arkansas for Medical Sciences and within the National Center for Toxicological Research.
Metrics
- h-index: 13
- Publications: 37
- Citations: 669
Selected Publications
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Dual Characteristics of Apoptosis and Survival in Cerebellar Purkinje Cells Four Days After Transient Global Ischemia (2026)
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Antibacterial efficacy and adaptive proteomic strategies of antibiotic-resistant pathogens on nanostructured copper surfaces (2026)
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Protein expression and morphological adaptations of Campylobacter jejuni under prolonged cold stress in chicken juice (2025)
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Quantitative proteomic and phenotypic responses of urinary pathogens to CuO/Cu₂O nanoparticles (2025)
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Examining the viability of five Salmonella enterica subsp. enterica in thymol at 4°C and 25°C using flow cytometry (2025)
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Species-Specific Stress Responses to Selenium Nanoparticles in Pseudomonas aeruginosa and Proteus mirabilis (2025)
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Proteomic insights into dual-species biofilm formation of E. coli and E. faecalis on urinary catheters (2025)
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A flow cytometric assay to detect viability and persistence of Salmonella enterica subsp. enterica serotypes in nuclease-free water at 4 and 25°C (2024)
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Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy (2022)
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Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model (2022)
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Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate (2022)
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Antimelanoma activities of chimeric thiazole–androstenone derivatives (2021)
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POS-066 MITIGATION OF ACUTE NEPHROTOXICITY IN MICE BY INHIBITION OF APOPTOTIC ENDONUCLEASE NETWORK (2021)
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4-4-(Anilinomethyl)-3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-ylbenzoic acid derivatives as potent anti-gram-positive bacterial agents (2021)
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TUNEL Assay: A Powerful Tool for Kidney Injury Evaluation (2021)
Collaboration Network
Top Collaborators
- TUNEL Assay: A Powerful Tool for Kidney Injury Evaluation
- Chronic Uremia Stimulates LDL Carbamylation and Atherosclerosis
- Carbamylated-Oxidized LDL: Proatherosclerotic Effects on Endothelial Cells and Macrophages
- Mechanism of graphene‐induced cytotoxicity: Role of endonucleases
- 4-4-(Anilinomethyl)-3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-ylbenzoic acid derivatives as potent anti-gram-positive bacterial agents
Showing 5 of 23 shared publications
- Chronic Uremia Stimulates LDL Carbamylation and Atherosclerosis
- Carbamylated-Oxidized LDL: Proatherosclerotic Effects on Endothelial Cells and Macrophages
- Deoxyribonuclease I is Essential for DNA Fragmentation Induced by Gamma Radiation in Mice
- Protective effect of zinc-N-acetylcysteine on the rat kidney during cold storage
- DNase I Induces Other Endonucleases in Kidney Tubular Epithelial Cells by Its DNA-Degrading Activity
Showing 5 of 8 shared publications
- Serotonin transporter protects the placental cells against apoptosis in caspase 3‐independent pathway
- Mechanism of graphene‐induced cytotoxicity: Role of endonucleases
- DNase I Induces Other Endonucleases in Kidney Tubular Epithelial Cells by Its DNA-Degrading Activity
- DNase activity in kidney cell pyknosis induced by serum deprivation
- Downregulation of DNase I expression by EndoG in kidney tubular epithelial cells
Showing 5 of 6 shared publications
- Protective effect of zinc-N-acetylcysteine on the rat kidney during cold storage
- Light-Powered Nanoconverters Cytotoxic to Breast Cancer Cells
- 298 Zinc-N-Acetylcysteine Protects Kidney During Cold Storage
- POS-066 MITIGATION OF ACUTE NEPHROTOXICITY IN MICE BY INHIBITION OF APOPTOTIC ENDONUCLEASE NETWORK
- Induction of kidney endonucleases by DNase I: evidence of endonuclease network
- A flow cytometric assay to detect viability and persistence of Salmonella enterica subsp. enterica serotypes in nuclease-free water at 4 and 25°C
- Proteomic insights into dual-species biofilm formation of E. coli and E. faecalis on urinary catheters
- Species-Specific Stress Responses to Selenium Nanoparticles in Pseudomonas aeruginosa and Proteus mirabilis
- Examining the viability of five Salmonella enterica subsp. enterica in thymol at 4°C and 25°C using flow cytometry
- Quantitative proteomic and phenotypic responses of urinary pathogens to CuO/Cu₂O nanoparticles
- Proteomic insights into dual-species biofilm formation of E. coli and E. faecalis on urinary catheters
- Species-Specific Stress Responses to Selenium Nanoparticles in Pseudomonas aeruginosa and Proteus mirabilis
- Antibacterial efficacy and adaptive proteomic strategies of antibiotic-resistant pathogens on nanostructured copper surfaces
- Quantitative proteomic and phenotypic responses of urinary pathogens to CuO/Cu₂O nanoparticles
- Protein expression and morphological adaptations of Campylobacter jejuni under prolonged cold stress in chicken juice
- Proteomic insights into dual-species biofilm formation of E. coli and E. faecalis on urinary catheters
- Species-Specific Stress Responses to Selenium Nanoparticles in Pseudomonas aeruginosa and Proteus mirabilis
- Antibacterial efficacy and adaptive proteomic strategies of antibiotic-resistant pathogens on nanostructured copper surfaces
- Quantitative proteomic and phenotypic responses of urinary pathogens to CuO/Cu₂O nanoparticles
- Protein expression and morphological adaptations of Campylobacter jejuni under prolonged cold stress in chicken juice
- Deoxyribonuclease I is Essential for DNA Fragmentation Induced by Gamma Radiation in Mice
- Protective effect of zinc-N-acetylcysteine on the rat kidney during cold storage
- 298 Zinc-N-Acetylcysteine Protects Kidney During Cold Storage
- Radioprotection by inactivation of deoxyribonuclease I
- Chronic Uremia Stimulates LDL Carbamylation and Atherosclerosis
- Carbamylated-Oxidized LDL: Proatherosclerotic Effects on Endothelial Cells and Macrophages
- ICAM‐1 is Key Molecule in Carbamylated LDL‐induced Monocyte Adhesion
- Induction of kidney endonucleases by DNase I: evidence of endonuclease network
- Proteomic insights into dual-species biofilm formation of E. coli and E. faecalis on urinary catheters
- Species-Specific Stress Responses to Selenium Nanoparticles in Pseudomonas aeruginosa and Proteus mirabilis
- Quantitative proteomic and phenotypic responses of urinary pathogens to CuO/Cu₂O nanoparticles
- Protein expression and morphological adaptations of Campylobacter jejuni under prolonged cold stress in chicken juice
- Deoxyribonuclease I is Essential for DNA Fragmentation Induced by Gamma Radiation in Mice
- Radioprotection by inactivation of deoxyribonuclease I
- Induction of kidney endonucleases by DNase I: evidence of endonuclease network
- Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate
- Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model
- Gamma-Tocotrienol Protects the Intestine from Radiation Potentially by Accelerating Mesenchymal Immune Cell Recovery
- Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate
- Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model
- Gamma-Tocotrienol Protects the Intestine from Radiation Potentially by Accelerating Mesenchymal Immune Cell Recovery
- DNase I Induces Other Endonucleases in Kidney Tubular Epithelial Cells by Its DNA-Degrading Activity
- Downregulation of DNase I expression by EndoG in kidney tubular epithelial cells
- Induction of kidney endonucleases by DNase I: evidence of endonuclease network
- Proteomic insights into dual-species biofilm formation of E. coli and E. faecalis on urinary catheters
- Species-Specific Stress Responses to Selenium Nanoparticles in Pseudomonas aeruginosa and Proteus mirabilis
- Quantitative proteomic and phenotypic responses of urinary pathogens to CuO/Cu₂O nanoparticles
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