Aaron J. Storey
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Also affiliated: Arkana Laboratories (2022–2026)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Aaron J. Storey's research investigates molecular mechanisms underlying cancer development and autoimmune diseases. His work has explored the role of chromatin dynamics, specifically aberrant looping and histone modifications, in promoting tumorigenesis. He has identified and studied novel autoantigens associated with membranous nephropathy, including NELL1 and HTRA1, in the context of malignancy and lupus nephritis.
Storey's laboratory employs techniques such as CRISPR-based proteomic analysis to investigate these processes. His research has also focused on specific oncogenic drivers, including PHF19's role in multiple myeloma through PRC2 activation and NSD3's involvement in cancer through cMyc nodes. He has published extensively on these topics, with a h-index of 24 and over 2,000 citations, and collaborates with several researchers at the University of Arkansas for Medical Sciences, including Ricky D. Edmondson, Samuel G. Mackintosh, Alan J. Tackett, and Sydnye L. Shuttleworth.
Metrics
- h-index: 24
- Publications: 145
- Citations: 2,112
Selected Publications
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Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 2 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 5 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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BAHCC1 binds H4K20me1 to facilitate the MCM complex loading and DNA replication (2025)
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The phenylalanine-and-glycine repeats of NUP98 oncofusions form condensates that selectively partition transcriptional coactivators (2025)
Collaboration Network
Top Collaborators
- Phase separation drives aberrant chromatin looping and cancer development
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma
Showing 5 of 41 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
Showing 5 of 36 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
Showing 5 of 33 shared publications
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data
Showing 5 of 24 shared publications
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot
- In Vivo Metabolic Tracing Demonstrates the Site‐Specific Contribution of Hepatic Ethanol Metabolism to Histone Acetylation
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags
Showing 5 of 22 shared publications
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags
- Dynamic global acetylation remodeling during the yeast heat shock response
- Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome using Tandem Mass Tags
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 15 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
Showing 5 of 14 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
- ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism
Showing 5 of 13 shared publications
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 13 shared publications
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 13 shared publications
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 13 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
Showing 5 of 12 shared publications
- NELL1 is a target antigen in malignancy-associated membranous nephropathy
- Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis
- Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy
- Transforming Growth Factor Beta Receptor 3 (TGFBR3)–Associated Membranous Nephropathy
- Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
Showing 5 of 11 shared publications
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 10 shared publications
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 3 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 4 of Dynamic global acetylation remodeling during the yeast heat shock response
- Additional file 1 of Dynamic global acetylation remodeling during the yeast heat shock response
Showing 5 of 10 shared publications
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