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Presence Current · Arkansas
Last published 2025
Sources OpenAlex · ORCID
Refreshed 2026-08-15

Susie L. Brown

Researcher

Also affiliated: Program for Appropriate Technology in Health (1985); University of Kentucky (1987); University of Washington (1985)

Faculty Researcher

7 h-index 9 pubs 348 cited

  • Animals
  • Malaria
  • Humans
  • Immunologic Memory
  • Plasmodium yoelii
  • Antigens, Surface
  • Cell Differentiation
  • T-Lymphocytes
  • Memory B Cells
  • Mice
  • Antibodies, Protozoan
  • Male
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Mice, Knockout

Biography and Research Information

OverviewAI-generated summary

Susie L. Brown's research investigates immunological memory, particularly in the context of malaria. Her work explores the heterogeneity of memory B cell populations, specifically IgM+ and IgM– memory B cells, and their capacity to produce class-switched antibodies and germinal center B cells upon rechallenge with Plasmodium yoelii. Brown also studies the role of non-canonical DNA structures, such as G-quadruplex and i-motif DNA, in gene regulation, examining their formation in the promoter region of MYD88, a key innate immune adaptor. Her research network includes collaborators Jason S. Stumhofer, Jonathan J. Bauer, Juhyung Lee, and Enatha Ntirandekura, all from the University of Arkansas for Medical Sciences, with whom she has co-authored multiple publications. Brown's scholarly output includes 9 publications with an h-index of 6 and 337 total citations.

Metrics

  • h-index: 7
  • Publications: 9
  • Citations: 348

Selected Publications

  • G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88 (2025)
    Cell Reports Physical Science 7 citations DOI OpenAlex
  • IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with <i>P. yoelii</i> (2022)
    Journal of Leukocyte Biology 15 citations DOI OpenAlex
  • IgM <sup>+</sup> and IgM <sup>-</sup> memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with <i>P. yoelii</i> (2021)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
  • The i-Motif as a Molecular Target: More Than a Complementary DNA Secondary Structure (2021)
    Pharmaceuticals 93 citations DOI OpenAlex
  • NK1.1 Expression Defines a Population of CD4+ Effector T Cells Displaying Th1 and Tfh Cell Properties That Support Early Antibody Production During Plasmodium yoelii Infection (2018)
    Frontiers in Immunology 14 citations DOI OpenAlex
  • IL-17 Promotes Differentiation of Splenic LSK− Lymphoid Progenitors into B Cells following <i>Plasmodium yoelii</i> Infection (2017)
    The Journal of Immunology 7 citations DOI OpenAlex

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Collaboration Network

13 Collaborators 2 Institutions 1 Country

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