Susie L. Brown
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Also affiliated: University of Kentucky (1987); University of Washington (1985)
Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Susie L. Brown's research focuses on the immune response to Plasmodium yoelii infection, particularly concerning B cell and T cell differentiation and function. Her recent work investigates how different B cell populations, including IgM+ and IgM– memory B cells, contribute to antibody production and germinal center formation upon rechallenge with the parasite. She also studies the role of NK1.1 expression in defining CD4+ effector T cells that support early antibody production during infection. Additionally, her research has explored the formation of G-quadruplex and i-motif DNA structures in the promoter of the innate immune adaptor MYD88, suggesting a link between DNA secondary structures and immune gene regulation. Brown collaborates with Jason S. Stumhofer, Jonathan J. Bauer, Juhyung Lee, and Enatha Ntirandekura, all from the University of Arkansas for Medical Sciences, with whom she has co-authored multiple publications. Her scholarship metrics include an h-index of 7, with 9 total publications and 350 citations.
Metrics
- h-index: 7
- Publications: 9
- Citations: 351
Selected Publications
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G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88 (2025)
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IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with P. yoelii (2022)
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IgM + and IgM - memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with P. yoelii (2021)
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The i-Motif as a Molecular Target: More Than a Complementary DNA Secondary Structure (2021)
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NK1.1 Expression Defines a Population of CD4+ Effector T Cells Displaying Th1 and Tfh Cell Properties That Support Early Antibody Production During Plasmodium yoelii Infection (2018)
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IL-17 Promotes Differentiation of Splenic LSK− Lymphoid Progenitors into B Cells following Plasmodium yoelii Infection (2017)
Collaboration Network
Top Collaborators
- NK1.1 Expression Defines a Population of CD4+ Effector T Cells Displaying Th1 and Tfh Cell Properties That Support Early Antibody Production During Plasmodium yoelii Infection
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with P. yoelii
- IL-17 Promotes Differentiation of Splenic LSK− Lymphoid Progenitors into B Cells following Plasmodium yoelii Infection
- IgM + and IgM - memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with P. yoelii
- NK1.1 Expression Defines a Population of CD4+ Effector T Cells Displaying Th1 and Tfh Cell Properties That Support Early Antibody Production During Plasmodium yoelii Infection
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with P. yoelii
- IgM + and IgM - memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with P. yoelii
- The i-Motif as a Molecular Target: More Than a Complementary DNA Secondary Structure
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with P. yoelii
- IgM + and IgM - memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with P. yoelii
- IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with P. yoelii
- IgM + and IgM - memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with P. yoelii
- IL-17 Promotes Differentiation of Splenic LSK− Lymphoid Progenitors into B Cells following Plasmodium yoelii Infection
- NK1.1 Expression Defines a Population of CD4+ Effector T Cells Displaying Th1 and Tfh Cell Properties That Support Early Antibody Production During Plasmodium yoelii Infection
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
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