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Presence Current · Arkansas
Last published 2025
Sources OpenAlex · ORCID
Refreshed 2026-10-08

Susie L. Brown

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Also affiliated: University of Kentucky (1987); University of Washington (1985)

7 h-index 9 pubs 351 cited

  • Animals
  • Malaria
  • Humans
  • Plasmodium yoelii
  • Immunologic Memory
  • Antigens, Surface
  • Cell Differentiation
  • T-Lymphocytes
  • Antibodies, Protozoan
  • Male
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Memory B Cells
  • Mice

Biography and Research Information

OverviewAI-generated summary

Susie L. Brown's research focuses on the immune response to Plasmodium yoelii infection, particularly concerning B cell and T cell differentiation and function. Her recent work investigates how different B cell populations, including IgM+ and IgM– memory B cells, contribute to antibody production and germinal center formation upon rechallenge with the parasite. She also studies the role of NK1.1 expression in defining CD4+ effector T cells that support early antibody production during infection. Additionally, her research has explored the formation of G-quadruplex and i-motif DNA structures in the promoter of the innate immune adaptor MYD88, suggesting a link between DNA secondary structures and immune gene regulation. Brown collaborates with Jason S. Stumhofer, Jonathan J. Bauer, Juhyung Lee, and Enatha Ntirandekura, all from the University of Arkansas for Medical Sciences, with whom she has co-authored multiple publications. Her scholarship metrics include an h-index of 7, with 9 total publications and 350 citations.

Metrics

  • h-index: 7
  • Publications: 9
  • Citations: 351

Selected Publications

  • G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88 (2025)
    Cell Reports Physical Science 8 citations DOI OpenAlex
  • IgM+ and IgM– memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon rechallenge with P. yoelii (2022)
    Journal of Leukocyte Biology 15 citations DOI OpenAlex
  • IgM + and IgM - memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with P. yoelii (2021)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
  • The i-Motif as a Molecular Target: More Than a Complementary DNA Secondary Structure (2021)
    Pharmaceuticals 95 citations DOI OpenAlex
  • NK1.1 Expression Defines a Population of CD4+ Effector T Cells Displaying Th1 and Tfh Cell Properties That Support Early Antibody Production During Plasmodium yoelii Infection (2018)
    Frontiers in Immunology 15 citations DOI OpenAlex
  • IL-17 Promotes Differentiation of Splenic LSK− Lymphoid Progenitors into B Cells following Plasmodium yoelii Infection (2017)
    The Journal of Immunology 7 citations DOI OpenAlex

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Collaboration Network

14 Collaborators 3 Institutions 1 Country

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