Horacio Gómez-Acevedo
Associate Professor
Also affiliated: Arkansas Children's Hospital (2010–2014); University of Alberta (2004); University of Arkansas Medical Center (2016–2021); Arkansas Children's Nutrition Center (2011–2016); Arkansas Children's Research Institute (2010)
Biomedical Informatics, College of Medicine
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Horacio Gómez-Acevedo's research focuses on the molecular and physiological impacts of maternal obesity on offspring development, particularly in the context of metabolic programming. His work investigates how factors like diet and in utero exposure to maternal obesity can disrupt circadian rhythms and alter gene expression and DNA methylation in offspring, leading to potential metabolic dysregulation. Gómez-Acevedo has also contributed to studies examining the placental environment in maternal obesity, including its lipotoxic aspects and the role of specific proteins in inflammation. His research portfolio includes investigations into viral infections, such as HTLV-I, exploring mathematical models for immune responses. With a career spanning over a decade, Gómez-Acevedo has published extensively, accumulating over 1,300 citations and an h-index of 18. He actively collaborates with researchers at the University of Arkansas for Medical Sciences and the University of Arkansas at Little Rock.
Metrics
- h-index: 18
- Publications: 106
- Citations: 1,369
Positions
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Associate Professor publications 2009–2026University of Arkansas for Medical Sciences Biomedical Informatics, College of Medicine Institutional directory
Selected Publications
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MSR157 COMPARISON OF SAMPLING STRATEGIES TO ADDRESS SEVERE DATA IMBALANCE AND COMPUTATIONAL BENCHMARKING FOR TIME-TO-EVENT PREDICTIVE MODEL DEVELOPMENT ACROSS LOCAL AND HIGH-PERFORMANCE COMPUTING ENVIRONMENTS: PREDICTION OF ALCOHOL USE DISORDER AND OPIOID USE DISORDER AMONG ARKANSAS MEDICAL MARIJUANA CARDHOLDERS (2026)
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Abstract 7642: Nicotine dependence partially mediates the association between <i>IP6K3</i> genetic variation and risk of lung squamous cell carcinoma among smokers (2026)
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Deletion of the scavenger receptor Scarb1 in osteoblast progenitors and myeloid cells does not affect bone mass (2025)
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A Tracts of Homozygosity Approach Identifies Methylation-Regulated <i>CSMD1</i> Expression Targets in Non–Small Cell Lung Cancers Related to Smoking Behavior (2025)
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MSR68 Development of a Discrete-Time-Updating Algorithm to Predict Cannabis Use Disorder Among Arkansas Medical Marijuana Cardholders (2025)
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MSR2 Developing a Feature Selection Workflow for Variable-Rich Data: A Case Study Utilizing Claims Data to Build Classifiers for the Prediction of Opioid Use Disorder Among Persons Authorized to Purchase Medical Cannabis (2025)
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MSR34 Development of a Novel Approach to Improve Binary Classification Prediction Tasks When Encountering Time-To-Event Data: Performance Comparison of Three Alternative Approaches To Predict Stimulant Use Disorder Among Persons Authorized To Purchase Medical Marijuana (2025)
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Deletion of the scavenger receptor <i>Scarb1</i> in osteoblast progenitors and myeloid cells does not affect bone mass (2025)
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An Activation Likelihood Estimation Meta-Analysis of Voxel-Based Morphometry Studies of Chemotherapy-Related Brain Volume Changes in Breast Cancer (2025)
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Exome Sequencing to Identify Novel Susceptibility Genes for Nonsyndromic Split‐Hand/Ft Malformation: A Report From the National Birth Defects Prevention Study (2025)
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Abstract 1923: A tract of homozygosity analysis reveals methylation-driven <i>CSMD1</i> expression in non-small cell lung cancers (2025)
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Fairness in Low Birthweight Predictive Models: Implications of Excluding Race/Ethnicity (2025)
Grants & Funding
As listed on this researcher's institutional profile.
- Birth Defects Study to Evaluate Pregnancy exposureS (BD-STEPS) Core? Arkansas Center and Stillbirth NIH Co-Investigator
- Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Principal Investigator
- Tumor Shape Analysis and its Implications on Prognosis and Treatment TRI Translational Research Institute Principal Investigator
- RFA-DD-18-001 Birth Defects Study To Evaluate Pregnancy exposures (BD-STEPS) II Core & Component B Steps -Stillbirth NIH Co-Investigator
Collaboration Network
Top Collaborators
- Maternal obesity is associated with a lipotoxic placental environment
- Maternal Obesity Enhances White Adipose Tissue Differentiation and Alters Genome-Scale DNA Methylation in Male Rat Offspring
- High Fat Diet and In Utero Exposure to Maternal Obesity Disrupts Circadian Rhythm and Leads to Metabolic Programming of Liver in Rat Offspring
- A comprehensive analysis of the human placenta transcriptome
- Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition
Showing 5 of 15 shared publications
- Maternal obesity is associated with a lipotoxic placental environment
- Maternal Obesity Enhances White Adipose Tissue Differentiation and Alters Genome-Scale DNA Methylation in Male Rat Offspring
- High Fat Diet and In Utero Exposure to Maternal Obesity Disrupts Circadian Rhythm and Leads to Metabolic Programming of Liver in Rat Offspring
- Early growth response protein-1 mediates lipotoxicity-associated placental inflammation: role in maternal obesity
- A comprehensive analysis of the human placenta transcriptome
Showing 5 of 15 shared publications
- Maternal Obesity Enhances White Adipose Tissue Differentiation and Alters Genome-Scale DNA Methylation in Male Rat Offspring
- Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition
- Female mice lacking p47<sup>phox</sup>have altered adipose tissue gene expression and are protected against high fat-induced obesity
- Mammary Gland Morphology and Gene Expression Differ in Female Rats Treated with 17β-Estradiol or Fed Soy Protein Isolate
- Uterine responses to feeding soy protein isolate and treatment with 17β-estradiol differ in ovariectomized female rats
Showing 5 of 11 shared publications
- Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency
- A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice
- RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass
- <i>Mmp-13</i> deletion in cells of the mesenchymal lineage increases bone mass, decreases endocortical osteoclast number, and attenuates the cortical bone loss caused by estrogen deficiency in mice
- Mmp13 deletion in mesenchymal cells increases bone mass and attenuates the cortical bone loss caused by estrogen deficiency
Showing 5 of 9 shared publications
- Neutralization of oxidized phospholipids attenuates age‐associated bone loss in mice
- Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency
- A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice
- Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass
- RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass
Showing 5 of 9 shared publications
- Neutralization of oxidized phospholipids attenuates age‐associated bone loss in mice
- A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice
- Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass
- RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass
- Deletion of the Scavenger Receptor Scarb1 in Myeloid Cells Does Not Affect Bone Mass
Showing 5 of 8 shared publications
- Neutralization of oxidized phospholipids attenuates age‐associated bone loss in mice
- A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice
- Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass
- RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass
- Deletion of the Scavenger Receptor Scarb1 in Myeloid Cells Does Not Affect Bone Mass
Showing 5 of 8 shared publications
- Maternal Obesity Enhances White Adipose Tissue Differentiation and Alters Genome-Scale DNA Methylation in Male Rat Offspring
- High Fat Diet and In Utero Exposure to Maternal Obesity Disrupts Circadian Rhythm and Leads to Metabolic Programming of Liver in Rat Offspring
- Early growth response protein-1 mediates lipotoxicity-associated placental inflammation: role in maternal obesity
- Transcriptomic and epigenomic landscapes during cell fusion in BeWo trophoblast cells
- RNA-seq analysis of the rat placentation site reveals maternal obesity-associated changes in placental and offspring thyroid hormone signaling
Showing 5 of 7 shared publications
- Neutralization of oxidized phospholipids attenuates age‐associated bone loss in mice
- Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass
- RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass
- Deletion of the Scavenger Receptor Scarb1 in Myeloid Cells Does Not Affect Bone Mass
- Retraction notice to “Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass” [Bone 170(2023) 116702]
Showing 5 of 7 shared publications
- Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition
- Mammary Gland Morphology and Gene Expression Differ in Female Rats Treated with 17β-Estradiol or Fed Soy Protein Isolate
- Feeding soy protein isolate and treatment with estradiol have different effects on mammary gland morphology and gene expression in weanling male and female rats
- Mammary gland morphology and gene expression signature of weanling male and female rats following exposure to exogenous estradiol
- Soy Formula Is Not Estrogenic and Does Not Result in Reproductive Toxicity in Male Piglets: Results from a Controlled Feeding Study
Showing 5 of 6 shared publications
- High Fat Diet and In Utero Exposure to Maternal Obesity Disrupts Circadian Rhythm and Leads to Metabolic Programming of Liver in Rat Offspring
- Mammary Gland Morphology and Gene Expression Differ in Female Rats Treated with 17β-Estradiol or Fed Soy Protein Isolate
- Uterine responses to feeding soy protein isolate and treatment with 17β-estradiol differ in ovariectomized female rats
- Feeding soy protein isolate and treatment with estradiol have different effects on mammary gland morphology and gene expression in weanling male and female rats
- Soy protein isolate feeding does not result in reproductive toxicity in the pre-pubertal rat testis
Showing 5 of 6 shared publications
- Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition
- Female mice lacking p47<sup>phox</sup>have altered adipose tissue gene expression and are protected against high fat-induced obesity
- Uterine responses to feeding soy protein isolate and treatment with 17β-estradiol differ in ovariectomized female rats
- Feeding soy protein isolate and treatment with estradiol have different effects on mammary gland morphology and gene expression in weanling male and female rats
- Mammary gland morphology and gene expression signature of weanling male and female rats following exposure to exogenous estradiol
Showing 5 of 6 shared publications
- Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass
- RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass
- Deletion of the Scavenger Receptor Scarb1 in Myeloid Cells Does Not Affect Bone Mass
- Retraction notice to “Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass” [Bone 170(2023) 116702]
- Deletion of the scavenger receptor <i>Scarb1</i> in osteoblast progenitors and myeloid cells does not affect bone mass
Showing 5 of 6 shared publications
- Maternal Obesity Enhances White Adipose Tissue Differentiation and Alters Genome-Scale DNA Methylation in Male Rat Offspring
- High Fat Diet and In Utero Exposure to Maternal Obesity Disrupts Circadian Rhythm and Leads to Metabolic Programming of Liver in Rat Offspring
- Transcriptomic and epigenomic landscapes during cell fusion in BeWo trophoblast cells
- RNA-seq analysis of the rat placentation site reveals maternal obesity-associated changes in placental and offspring thyroid hormone signaling
- Maternal obesity and post‐natal high fat diet disrupt hepatic circadian rhythm in rat offspring
- Maternal obesity is associated with a lipotoxic placental environment
- Early growth response protein-1 mediates lipotoxicity-associated placental inflammation: role in maternal obesity
- A comprehensive analysis of the human placenta transcriptome
- Transcriptomic and epigenomic landscapes during cell fusion in BeWo trophoblast cells
- RNA-seq analysis of the rat placentation site reveals maternal obesity-associated changes in placental and offspring thyroid hormone signaling
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