Michela Palmieri

High Impact

RTDA

UAMS

Faculty Researcher

35 h-index 83 pubs 10,876 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website Research Group

OverviewAI-generated summary

Michela Palmieri's research focuses on understanding disease mechanisms and exploring therapeutic strategies, with a significant emphasis on bone metabolism, cancer, and neurological disorders. Her work has investigated the role of specific molecular pathways and cellular components in disease progression and treatment resistance. For instance, she has studied the contribution of senescent osteocytes to bone destruction in breast cancer metastasis and explored the signaling axis in multiple myeloma that promotes chemoresistance.

In the realm of bone health, Palmieri has examined factors influencing bone loss and resorption. This includes investigating the impact of osteocyte expression of osteoprotegerin on bone resorption following denosumab discontinuation and the neutralization of oxidized phospholipids as a means to attenuate age-associated bone loss in mice. Her research also delves into neurological conditions, examining autophagic imbalances and potential therapeutic insights in Mecp2-deficient models, relevant to conditions like Rett syndrome.

Palmieri collaborates extensively with researchers at the University of Arkansas for Medical Sciences, including Elena Ambrogini, Teenamol E. Joseph, Charles A. O’Brien, and Horacio Gómez-Acevedo, with whom she has co-authored numerous publications. Her scholarly output is substantial, evidenced by 83 total publications and over 10,000 citations, contributing to her designation as a highly cited researcher.

Metrics

h-index: 35
Publications: 83
Citations: 10,876

Selected Publications

Deletion of the scavenger receptor Scarb1 in osteoblast progenitors and myeloid cells does not affect bone mass (2025)

PLoS ONE DOI OpenAlex
Deletion of the scavenger receptor <i>Scarb1</i> in osteoblast progenitors and myeloid cells does not affect bone mass (2025)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans (2025)

Scientific Reports 1 citation DOI OpenAlex
Senolytics deplete senescent osteocytes and improve bone health in metastatic breast cancer (2024)

Journal of bone oncology DOI OpenAlex
Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis (2024)

Research Square 3 citations DOI OpenAlex
A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma (2024)

Haematologica 10 citations DOI OpenAlex
OR27-02 The Bone Anabolic Effect Of An Antibody Blocking Oxidized Phospholipids Is Associated With An Increase In Wnt10b In Osteoblasts. (2023)

Journal of the Endocrine Society DOI OpenAlex
Retraction notice to “Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass” [Bone 170(2023) 116702] (2023)

Bone DOI OpenAlex
Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation (2023)

JCI Insight 53 citations DOI OpenAlex
RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass (2023)

Bone 2 citations DOI OpenAlex
Deletion of the Scavenger Receptor Scarb1 in Myeloid Cells Does Not Affect Bone Mass (2022)

SSRN Electronic Journal DOI OpenAlex
Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass (2022)

PLoS ONE 2 citations DOI OpenAlex
Neutralization of oxidized phospholipids attenuates age‐associated bone loss in mice (2021)

Aging Cell 31 citations DOI OpenAlex
Osteoblasts Suppress Bone Resorption Via Production of Osteoprotegerin (2020)

SSRN Electronic Journal DOI OpenAlex
A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice (2020)

Journal of Bone and Mineral Research 17 citations DOI OpenAlex