Match tier
Confirmed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-08-17
M
Michael L. Blackburn
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
High Impact
Research Associate III
Also affiliated: Arkansas Children's Hospital (2014–2024); University of Washington (2003–2004); University of Arkansas Medical Center (2020); Arkansas Cardiology (2012); VA Puget Sound Health Care System (2003–2008); University of Applied Management Studies (2024); Winthrop Rockefeller Foundation (2025); Arkansas Children's Nutrition Center (2008–2025); Arkansas Department of Agriculture (2021)
Postdoc Researcher
26 h-index
77 pubs
2,207 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Michael L. Blackburn's research focuses on the physiological and molecular mechanisms underlying bone health, metabolism, and related conditions, primarily utilizing mouse and rat models. His work investigates the impact of dietary factors, such as high-fat diets and phenolic acids, on bone development and the prevention of bone loss, particularly in contexts of sex-steroid deficiency. Blackburn has explored the role of specific genes and cellular processes, including Nox4 expression in osteo-progenitors and the function of Ezh2 in myeloid cells, in regulating bone formation and resorption.
Further research includes examining the metabolic physiology of myoglobin knockout mice, exploring potential roles for globins in adipose tissue, and assessing the impact of soy-based formulas on reproductive health in piglets. He also investigates genetic factors, such as GPR109A, in ameliorating bone loss. Blackburn's scholarship metrics include an h-index of 26, with 77 total publications and 2,165 total citations, designating him as a highly cited researcher. He collaborates with researchers from the University of Arkansas at Fayetteville and the University of Arkansas for Medical Sciences, including Jin‐Ran Chen, Oxana P. Lazarenko, Perry C. Caviness, and Umesh D. Wankhade, and leads a research group.
Metrics
- h-index: 26
- Publications: 77
- Citations: 2,207
Selected Publications
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Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications (2025)
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Sex dependent effects of GPR109A gene deletion in myeloid cells on bone development in mice (2025)
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Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption (2025)
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Cystatin M/E ameliorates bone resorption through increasing osteoclastic cell estrogen influx (2024)
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Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice (2024)
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Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model (2023)
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Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice (2022)
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Nox4 expression in osteo-progenitors controls bone development in mice during early life (2022)
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GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice (2022)
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Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice (2021)
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On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice (2021)
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<scp>Short‐Term</scp> Increased Physical Activity During Early Life Affects High‐Fat <scp>Diet–Induced</scp> Bone Loss in Young Adult Mice (2021)
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Ezh2 mediates epigenetic regulation of osteoclastogenesis and bone remodeling in mice (2021)
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Carnitine palmitoyltransferase 2 knockout potentiates palmitate-induced insulin resistance in C<sub>2</sub>C<sub>12</sub>myotubes (2020)
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Increased Physical Activity During Early Life Exacerbates High Fat Diet-Induced Bone Loss in Adult Mice (2020)
Collaboration Network
Top Collaborators
Jin‐Ran Chen
Arkansas Children's Nutrition Center
11 shared publications
In database
- Nox4 expression in osteo-progenitors controls bone development in mice during early life
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice
Showing 5 of 11 shared publications
Oxana P. Lazarenko
Arkansas Children's Nutrition Center
11 shared publications
In database
- Nox4 expression in osteo-progenitors controls bone development in mice during early life
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice
Showing 5 of 11 shared publications
Perry C. Caviness
Arkansas Children's Nutrition Center
6 shared publications
In database
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
- Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications
Showing 5 of 6 shared publications
Dongzheng Gai
Winthrop Rockefeller Foundation
4 shared publications
In database
- Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
- Ezh2 mediates epigenetic regulation of osteoclastogenesis and bone remodeling in mice
- Cystatin M/E ameliorates bone resorption through increasing osteoclastic cell estrogen influx
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
Fenghuang Zhan
Winthrop Rockefeller Foundation
4 shared publications
In database
- Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- Ezh2 mediates epigenetic regulation of osteoclastogenesis and bone remodeling in mice
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
Jennifer F. Chen
Arkansas Children's Nutrition Center
4 shared publications
In database
- Nox4 expression in osteo-progenitors controls bone development in mice during early life
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
- Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications
Umesh D. Wankhade
Arkansas Children's Nutrition Center
3 shared publications
In database
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- <scp>Short‐Term</scp> Increased Physical Activity During Early Life Affects High‐Fat <scp>Diet–Induced</scp> Bone Loss in Young Adult Mice
Christopher E. Randolph
Arkansas Children's Hospital
3 shared publications
In database
- Nox4 expression in osteo-progenitors controls bone development in mice during early life
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
Kartik Shankar
University of Colorado Denver (US)
2 shared publications
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- <scp>Short‐Term</scp> Increased Physical Activity During Early Life Affects High‐Fat <scp>Diet–Induced</scp> Bone Loss in Young Adult Mice
Kikumi D. Ono‐Moore
Arkansas Children's Nutrition Center (US)
2 shared publications
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
Sree V. Chintapalli
University of Arkansas for Medical Sciences
2 shared publications
In database
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
Jennifer M. Rutkowsky
University of California, Davis (US)
2 shared publications
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
Brandon Willis
University of California, Davis (US)
2 shared publications
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
Todd Tolentino
University of California, Davis (US)
2 shared publications
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
K. C. Kent Lloyd
University of California, Davis (US)
2 shared publications
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Metabolic physiology and skeletal muscle phenotypes in male and female myoglobin knockout mice
Similar Researchers
Based on overlapping research topics
Perry C. Caviness
University of Arkansas for Medical Sciences
Bone Metabolism and Diseases
Diet and metabolism studies
Metabolism and Genetic Disorders
Sudipta Baroi
University of Arkansas for Medical Sciences
Bone Metabolism and Diseases
Diet and metabolism studies
Metabolism and Genetic Disorders
Christopher E. Randolph
University of Arkansas for Medical Sciences
Bone Metabolism and Diseases
Diet and metabolism studies
Metabolism and Genetic Disorders
P. Maharjan
University of Arkansas at Fayetteville
Diet and metabolism studies
Metabolism and Genetic Disorders
Animal Nutrition and Physiology
Oxana P. Lazarenko
University of Arkansas for Medical Sciences
Bone Metabolism and Diseases
Diet and metabolism studies
Epigenetics and DNA Methylation
Shari Gaudette
University of Arkansas for Medical Sciences
Diet and metabolism studies
Metabolism and Genetic Disorders
Epigenetics and DNA Methylation