Abdelrahman Y. Fouda
Associate Professor with tenure
Also affiliated: Georgia College & State University (2014–2017); Cairo University (2016–2026); University of Waterloo (2017); Jordan University of Science and Technology (2016); University of Georgia (2013–2019); Augusta University (2014–2023); Discovery Institute (2015–2023); Charlie Norwood VA Medical Center (2013–2022); Augusta University Health (2017–2023)
Faculty Researcher
Pharmacology & Toxicology, College of Medicine
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Abdelrahman Y. Fouda studies the mechanisms of retinal injury and potential therapeutic interventions, with a particular focus on the role of arginase enzymes. His research investigates how arginase 1 and arginase 2 contribute to retinal ischemia-reperfusion injury, a condition that can lead to vision loss. Fouda's work explores the pathways by which these enzymes induce mitochondrial dysfunction and promote or suppress neovascularization in the retina.
His laboratory is actively engaged in preclinical investigations of novel treatments. This includes the evaluation of pegylated arginase 1 as a therapeutic agent for retinal and brain injuries. Fouda also examines the interplay between myeloid cells and ischemic retinopathies, seeking to understand their role in the disease process and identify targets for intervention. His research has been supported by grants from the NIH/National Eye Institute, including funding for studies on retinal neurovascular protection through efferocytosis and the role of arginase 1 in retinal ischemia-reperfusion injury.
Fouda's publication record includes work on cysteine oxidation in copper transporter CTR1 and its link to VEGFR2 signaling and angiogenesis, as well as the investigation of retinal metabolic function in diabetic mouse models. He has a strong publication record with 89 total publications, an h-index of 28, and over 2,000 citations. He collaborates extensively with researchers at the University of Arkansas for Medical Sciences, including Esraa Shosha, Carol Morris, and Rami Ahmad Shahror.
Metrics
- h-index: 28
- Publications: 89
- Citations: 2,124
Selected Publications
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Association between primary open-angle glaucoma and retinal artery occlusions (2026)
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CD5L promotes efferocytosis and resolution of retinal ischemic injury (2026)
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Myeloid HDAC3 deletion protects against traumatic optic injury (2026)
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A metabolic switch in retinal angiogenesis: Histone deacetylase 3 (2026)
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Recent advances and future challenges in nanosystems for ocular drug delivery (2025)
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Systemic Lactate Dehydrogenase Levels as a Predictor of Progression from Non-Proliferative to Proliferative Diabetic Retinopathy (2025)
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HDAC3 mediates retinal endothelial cell metabolic reprogramming and angiogenesis (2025)
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Myeloid HDAC3 Deletion Protects Against Traumatic Optic Injury (2025)
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Extracellular Vesicle Metabolomics Holds Promise for Adult Axon Regeneration (2025)
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Disrupting the CD47/SIRPα Axis Protects Against Traumatic Optic Neuropathy (2025)
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HDAC3 Drives Retinal Endothelial Cell Angiogenesis: Potential Therapeutic Implications for Retinopathy (Abstract ID: 161164) (2025)
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Disrupting the CD47/SIRPα Axis as a Novel and Translational Therapy for Stroke (Abstract ID: 161422) (2025)
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Efferocytosis and retinal clean-up: Role of histone deacetylase 3 in ischemic retinopathy (2025)
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Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology (2024)
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Deletion of myeloid HDAC3 promotes efferocytosis to ameliorate retinal ischemic injury (2024)
Federal Grants 2 $502,702 total
Collaboration Network
Top Collaborators
- Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
- Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury
- Investigation of Retinal Metabolic Function in Type 1 Diabetic Akita Mice
- Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology
- Efferocytosis and retinal clean-up: Role of histone deacetylase 3 in ischemic retinopathy
Showing 5 of 9 shared publications
- Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis
- Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
- Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury
- Investigation of Retinal Metabolic Function in Type 1 Diabetic Akita Mice
- Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
Showing 5 of 6 shared publications
- Multi-color Flow Cytometry Protocol to Characterize Myeloid Cells in Mouse Retina Research
- Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology
- Recent advances and future challenges in nanosystems for ocular drug delivery
- Disrupting the CD47/SIRPα Axis Protects Against Traumatic Optic Neuropathy
- Myeloid HDAC3 Deletion Protects Against Traumatic Optic Injury
Showing 5 of 6 shared publications
- Multi-color Flow Cytometry Protocol to Characterize Myeloid Cells in Mouse Retina Research
- Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology
- Disrupting the CD47/SIRPα Axis as a Novel and Translational Therapy for Stroke (Abstract ID: 161422)
- Disrupting the CD47/SIRPα Axis Protects Against Traumatic Optic Neuropathy
- Myeloid HDAC3 deletion protects against traumatic optic injury
- Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
- Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury
- Investigation of Retinal Metabolic Function in Type 1 Diabetic Akita Mice
- Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
- Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
- Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury
- Investigation of Retinal Metabolic Function in Type 1 Diabetic Akita Mice
- Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
- Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
- Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury
- Investigation of Retinal Metabolic Function in Type 1 Diabetic Akita Mice
- Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
- Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
- Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury
- Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
- The mouse model of experimental autoimmune encephalomyelitis: Methods to study neuroinflammation in optic neuritis
- Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
- Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury
- Investigation of Retinal Metabolic Function in Type 1 Diabetic Akita Mice
- Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
- Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
- Investigation of Retinal Metabolic Function in Type 1 Diabetic Akita Mice
- Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
- Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
- Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury
- Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush
- The mouse model of experimental autoimmune encephalomyelitis: Methods to study neuroinflammation in optic neuritis
- Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology
- Disrupting the CD47/SIRPα Axis Protects Against Traumatic Optic Neuropathy
- Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology
- HDAC3 Drives Retinal Endothelial Cell Angiogenesis: Potential Therapeutic Implications for Retinopathy (Abstract ID: 161164)
- Proteomic Analysis of Aqueous Humor in Central Retinal Artery Occlusion: Unveiling Novel Insights Into Disease Pathophysiology
- Systemic Lactate Dehydrogenase Levels as a Predictor of Progression from Non-Proliferative to Proliferative Diabetic Retinopathy
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