Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
Biography and Research Information
OverviewAI-generated summary
Yunping Guo's research focuses on the intersection of the immune system and hypertension, particularly investigating the role of CD8-positive T-lymphocytes in disease progression. Guo has published work examining how the IFNγ-PDL1 pathway influences the interaction between CD8+ T cells and distal convoluted tubules, contributing to salt-sensitive hypertension. Further research explores the P2X7 receptor's role in antigen-independent T cell activation that promotes this condition. Guo also investigates the contribution of immune memory to chronic hypertension recurrence and examines innate immune components in hypertension-induced cardiac dysfunction. Collaborations include extensive work with Shengyu Mu, Katherine Deck, and Christoph Mora at the University of Arkansas for Medical Sciences, with whom Guo shares numerous publications.
Metrics
- h-index: 3
- Publications: 17
- Citations: 70
Selected Publications
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Kidney Resident Memory CD8+ T cells drive the immortality of hypertension (2026)
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Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension (2026)
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Abstract P200: Immune memory contributes to chronic hypertension recurrence (2024)
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Abstract P335: An innate immune component in hypertension-induced cardiac dysfunction Christoph Mora, Katherine Deck, Yunmeng Liu, Lance Benson, Tonya Rafferty, & Shengyu Mu (2024)
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P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION (2024)
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O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION (2024)
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Kidney resident memory CD8 T cells mediate recurrence of salt-sensitive hypertension (2024)
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Macrophage to Myofibroblast Transition Promotes Hypertension-Induced Cardiac Diastolic Dysfunction (2024)
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<i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension (2024)
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Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development (2023)
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The link between immunity and hypertension in the kidney and heart (2023)
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S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION (2023)
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The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension (2022)
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The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension (2022)
Collaboration Network
Top Collaborators
Lance Benson
University of Arkansas for Medical Sciences (US)
10 shared publications
- The link between immunity and hypertension in the kidney and heart
- The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
- Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development
- Macrophage to Myofibroblast Transition Promotes Hypertension-Induced Cardiac Diastolic Dysfunction
Showing 5 of 10 shared publications
Shengyu Mu
University of Arkansas for Medical Sciences
10 shared publications
In database
- The link between immunity and hypertension in the kidney and heart
- The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
- Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development
- Macrophage to Myofibroblast Transition Promotes Hypertension-Induced Cardiac Diastolic Dysfunction
Showing 5 of 10 shared publications
Yunmeng Liu
University of Arkansas for Medical Sciences
9 shared publications
In database
- The link between immunity and hypertension in the kidney and heart
- The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
- Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development
- Macrophage to Myofibroblast Transition Promotes Hypertension-Induced Cardiac Diastolic Dysfunction
Showing 5 of 9 shared publications
Katherine Deck
University of Arkansas for Medical Sciences
9 shared publications
In database
- The link between immunity and hypertension in the kidney and heart
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
- Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development
- Macrophage to Myofibroblast Transition Promotes Hypertension-Induced Cardiac Diastolic Dysfunction
- Kidney resident memory CD8 T cells mediate recurrence of salt-sensitive hypertension
Showing 5 of 9 shared publications
Christoph Mora
University of Arkansas for Medical Sciences
9 shared publications
In database
- The link between immunity and hypertension in the kidney and heart
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
- Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development
- Macrophage to Myofibroblast Transition Promotes Hypertension-Induced Cardiac Diastolic Dysfunction
- Kidney resident memory CD8 T cells mediate recurrence of salt-sensitive hypertension
Showing 5 of 9 shared publications
Yunzhao Xiong
University of Arkansas for Medical Sciences (US)
2 shared publications
- The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
Tonya Rafferty
University of Arkansas for Medical Sciences
2 shared publications
In database
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
Yunmeng Liu
University of Arkansas for Medical Sciences
1 shared publication
In database
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
Tonya Rafferty
University of Arkansas for Medical Sciences
1 shared publication
In database
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
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