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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-09
Antiño R. Allen
◆ ARA Academy
Federal Grant PI
High Impact
Professor
Also affiliated: San Francisco General Hospital (2012); Children's Hospital of Philadelphia (2022); University of California, San Francisco (2012–2013); University of Arkansas Medical Center (2018)
26 h-index
83 pubs
2,046 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Antiño R. Allen's research program investigates the biological effects of radiation exposure on the central nervous system, with a particular focus on the hippocampus and its role in cognitive function. His work has examined the impacts of various types of radiation, including cosmic radiation and proton beams, on neuronal structures like dendritic spines.
Dr. Allen has received federal funding for his research, including a $307,350 NIH/National Cancer Institute grant to explore the use of MnBuOE as a novel chemosensitizer for breast cancer and as a neuroprotector. He has also served as Co-PI on other NIH-funded initiatives, such as the Cancer Education and Research Program (CERP) and the Initiative for Maximizing Student Development (IMSD), totaling over $496,000 in funding across these awards. His scholarship is recognized by his membership in the ARA Academy and his designation as a high-impact researcher, evidenced by an h-index of 26 and over 2,000 citations across his 87 publications. He actively collaborates with researchers at the University of Arkansas for Medical Sciences, including Pilar Simmons and Taylor McElroy.
Metrics
- h-index: 26
- Publications: 83
- Citations: 2,046
Positions
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Professor 2013–presentUniversity of Arkansas for Medical Sciences College of Pharmacy Institutional directory
Selected Publications
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Changes in gut, microbiome, and cognition after doxorubicin, cyclophosphamide, and paclitaxel chemotherapy treatment (2026)
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Implications of cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy on hippocampal-dependent cognition and gut microbiome (2025)
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Manganese Superoxide Dismutase: Structure, Function, and Implications in Human Disease (2025)
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The adverse effects of chemotherapy on bone mass are not prevented by senolytics (2025)
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A Bibliometric Analysis of Research Examining How Space Radiation Affects Human and Rodent Cognition, 1990–2023 (2024)
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MnSOD Mimetics in Therapy: Exploring Their Role in Combating Oxidative Stress-Related Diseases (2024)
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Summer undergraduate biomedical research program for underrepresented minority students in a rural, low-income state (2024)
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Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior (2023)
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Sulforaphane’s Multifaceted Potential: From Neuroprotection to Anticancer Action (2023)
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Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart (2023)
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Abstract P3-08-08: Establishment of a Breast Cancer Rat Model of Chemotherapy-Induced Cardiotoxicity (2023)
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Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model (2023)
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Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, And Cognition in an Aged Murine Model (2022)
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Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model (2022)
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Chemotherapy induced oxidative stress in the ovary: drug-dependent mechanisms and potential interventions (2022)
ARA Academy 2023 ARA Fellow
Dr. Allen is an Associate Professor and Graduate Program Director at the Division of Radiation Health, Department of Pharmaceutical Sciences at UAMS. He holds a PhD in Evolution, Ecology, and Behavior and served as a Captain in the US Army Infantry from 2004-2010. His work focuses on community science development and introducing research and discovery to underserved populations in Arkansas.
Policy Impact
Builds research capacity and STEM engagement in underserved Arkansas communities, expanding the state's scientific workforce pipeline and health research infrastructure.
Growth Areas
['Population Health Innovations & Clinical Research']
Federal Grants 3 $803,779 total
NIH
Co-PI
Sep 2026 - Aug 2031
NIH
Co-PI
Feb 2024 - Apr 2025
NIH
Contact PI
Aug 2021 - Jul 2025
MnBuOE as a Novel Chemosensitizer for Breast Cancer and Neuroprotector
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- The Protein C Pathway in Mitigation of Radiation-Induced Endothelial and Vascular Dysfunction NIH
- Center for Studies of Host Response to Cancer Therapy NIH
- Carcinogenesis and Central Nervous System Risks for Space Radiation National Aeronautics & Space Administration via Loma Linda University Medical Center
- Metabolomics Based Prediction of Delayed Effects of Acute Radiation Exposure NIH/Nat. Inst. of Allergy & Infectious Diseases via Nelson Scientific Labs, LLC
- EPSCoR - CASE Summer National Science Foundation via Arkansas Economic Development Commission
- ABI P. Prather NIH T32 FY26 Y3 State of Arkansas
- RII Track-1: Arkansas ASSET Initiative III - Continuation Y5 - Continuation National Science Foundation via Arkansas Economic Development Commission
- Photobiomodulation to Ameliorate Neuronal Degeneration and Cognitive Decline after Mixed Field Irradiation - Continuation National Aeronautics & Space Administration
- Development of a minimally invasive biomarker assay to detect delayed radiation injury NIH
- Development of a minimally invasive biomarker assay to detect delayed radiation injury NIH/Nat. Inst. of Allergy & Infectious Diseases
- Functional optical biomarkers of response to therapy in head and neck squamous cell carcinoma- Resubmission Arkansas Economic Development Commission via National Science Foundation
- Compromised function of a glial glucose transporter in aging and Alzheimer's disease NIH
Collaboration Network
Top Collaborators
Frederico Kiffer
Children's Hospital of Philadelphia (US)
16 shared publications
- Behavioral effects of space radiation: A comprehensive review of animal studies
- 5-Fluorouracil chemotherapy upregulates cytokines and alters hippocampal dendritic complexity in aged mice
- Long-Term Changes in Cognition and Physiology after Low-Dose 16O Irradiation
- Early effects of 16O radiation on neuronal morphology and cognition in a murine model
- Late Effects of 16O-Particle Radiation on Female Social and Cognitive Behavior and Hippocampal Physiology
Showing 5 of 16 shared publications
Thomas Groves
University of Arkansas for Medical Sciences
15 shared publications
In database
- 5-Fluorouracil chemotherapy upregulates cytokines and alters hippocampal dendritic complexity in aged mice
- Early effects of 16O radiation on neuronal morphology and cognition in a murine model
- Late Effects of 16O-Particle Radiation on Female Social and Cognitive Behavior and Hippocampal Physiology
- Alzheimer amyloid-β- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood
- Effects of1H +16O Charged Particle Irradiation on Short-Term Memory and Hippocampal Physiology in a Murine Model
Showing 5 of 15 shared publications
Taylor McElroy
University of Arkansas for Medical Sciences
15 shared publications
In database
- Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment
- Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide
- Early Effects of Cyclophosphamide, Methotrexate, and 5-Fluorouracil on Neuronal Morphology and Hippocampal-Dependent Behavior in a Murine Model
- Assessing the Effects of Redox Modifier MnTnBuOE-2-PyP 5+ on Cognition and Hippocampal Physiology Following Doxorubicin, Cyclophosphamide, and Paclitaxel Treatment
- Late Effects of 1H + 16O on Short-Term and Object Memory, Hippocampal Dendritic Morphology and Mutagenesis
Showing 5 of 15 shared publications
Tyler Alexander
University of Arkansas for Medical Sciences (US)
14 shared publications
- 5-Fluorouracil chemotherapy upregulates cytokines and alters hippocampal dendritic complexity in aged mice
- Long-Term Changes in Cognition and Physiology after Low-Dose 16O Irradiation
- Early effects of 16O radiation on neuronal morphology and cognition in a murine model
- Late Effects of 16O-Particle Radiation on Female Social and Cognitive Behavior and Hippocampal Physiology
- Effects of1H +16O Charged Particle Irradiation on Short-Term Memory and Hippocampal Physiology in a Murine Model
Showing 5 of 14 shared publications
Marjan Boerma
University of Arkansas for Medical Sciences
14 shared publications
In database
- Behavioral effects of space radiation: A comprehensive review of animal studies
- 5-Fluorouracil chemotherapy upregulates cytokines and alters hippocampal dendritic complexity in aged mice
- Long-Term Changes in Cognition and Physiology after Low-Dose 16O Irradiation
- Early effects of 16O radiation on neuronal morphology and cognition in a murine model
- Late Effects of 16O-Particle Radiation on Female Social and Cognitive Behavior and Hippocampal Physiology
Showing 5 of 14 shared publications
Pilar Simmons
University of Arkansas for Medical Sciences
12 shared publications
In database
- Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment
- Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide
- Tocotrienols as an Anti-Breast Cancer Agent
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior
Showing 5 of 12 shared publications
Jing Wang
University of Arkansas for Medical Sciences (US)
11 shared publications
- 5-Fluorouracil chemotherapy upregulates cytokines and alters hippocampal dendritic complexity in aged mice
- Long-Term Changes in Cognition and Physiology after Low-Dose 16O Irradiation
- Early effects of 16O radiation on neuronal morphology and cognition in a murine model
- Late Effects of 16O-Particle Radiation on Female Social and Cognitive Behavior and Hippocampal Physiology
- Effects of1H +16O Charged Particle Irradiation on Short-Term Memory and Hippocampal Physiology in a Murine Model
Showing 5 of 11 shared publications
Vijayalakshmi Sridharan
University of Arkansas for Medical Sciences
10 shared publications
In database
- Long-Term Changes in Cognition and Physiology after Low-Dose 16O Irradiation
- Late Effects of 16O-Particle Radiation on Female Social and Cognitive Behavior and Hippocampal Physiology
- Effects of1H +16O Charged Particle Irradiation on Short-Term Memory and Hippocampal Physiology in a Murine Model
- Late Effects of 1H + 16O on Short-Term and Object Memory, Hippocampal Dendritic Morphology and Mutagenesis
- Late effects of 1H irradiation on hippocampal physiology
Showing 5 of 10 shared publications
Jacob Raber
Oregon National Primate Research Center (US)
9 shared publications
- Exposure to Low-Dose 56Fe-Ion Radiation Induces Long-Term Epigenetic Alterations in Mouse Bone Marrow Hematopoietic Progenitor and Stem Cells
- 56Fe Irradiation Alters Spine Density and Dendritic Complexity in the Mouse Hippocampus
- Long-term epigenetic effects of exposure to low doses of 56Fe in the mouse lung
- Densely ionizing radiation affects DNA methylation of selective LINE-1 elements
- Radiation exposure prior to traumatic brain injury induces responses that differ as a function of animal age
Showing 5 of 9 shared publications
J Anderson
University of Arkansas for Medical Sciences (US)
9 shared publications
- 5-Fluorouracil chemotherapy upregulates cytokines and alters hippocampal dendritic complexity in aged mice
- Effects of Cyclophosphamide and/or Doxorubicin in a Murine Model of Postchemotherapy Cognitive Impairment
- Late Effects of 16O-Particle Radiation on Female Social and Cognitive Behavior and Hippocampal Physiology
- Effects of1H +16O Charged Particle Irradiation on Short-Term Memory and Hippocampal Physiology in a Murine Model
- Changes in cognition and dendritic complexity following intrathecal methotrexate and cytarabine treatment in a juvenile murine model
Showing 5 of 9 shared publications
Madison Trujillo
University of Arkansas for Medical Sciences (US)
9 shared publications
- Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment
- Early Effects of Cyclophosphamide, Methotrexate, and 5-Fluorouracil on Neuronal Morphology and Hippocampal-Dependent Behavior in a Murine Model
- Chemotherapy induced oxidative stress in the ovary: drug-dependent mechanisms and potential interventions
- Tocotrienols as an Anti-Breast Cancer Agent
- Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior
Showing 5 of 9 shared publications
Christa Corley
University of Arkansas for Medical Sciences
8 shared publications
In database
- Tocotrienols as an Anti-Breast Cancer Agent
- Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior
- The Effects of 5-Fluorouracil/Leucovorin Chemotherapy on Cognitive Function in Male Mice
- A Bibliometric Analysis of Cyclophosphamide, Methotrexate, and Fluorouracil Breast Cancer Treatments: Implication for the Role of Inflammation in Cognitive Dysfunction
- Cranial irradiation impairs juvenile social memory and modulates hippocampal physiology
Showing 5 of 8 shared publications
Kimberly J. Krager
University of Arkansas for Medical Sciences
7 shared publications
In database
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Behavioral Effects of Focal Irradiation in a Juvenile Murine Model
- Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model
- The sex-dependent impact of SIRT3 on cognition
Showing 5 of 7 shared publications
Nükhet Aykin‐Burns
University of Arkansas for Medical Sciences
7 shared publications
In database
- Chemotherapy induced oxidative stress in the ovary: drug-dependent mechanisms and potential interventions
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model
- The sex-dependent impact of SIRT3 on cognition
Showing 5 of 7 shared publications
Taurean Brown
University of Arkansas for Medical Sciences
7 shared publications
In database
- Implications of Breast Cancer Chemotherapy-Induced Inflammation on the Gut, Liver, and Central Nervous System
- Piperlongumine as a Neuro-Protectant in Chemotherapy Induced Cognitive Impairment
- Cognitive impairment resulting from treatment with docetaxel, doxorubicin, and cyclophosphamide
- Assessing the Effects of Redox Modifier MnTnBuOE-2-PyP 5+ on Cognition and Hippocampal Physiology Following Doxorubicin, Cyclophosphamide, and Paclitaxel Treatment
- Cranial irradiation impairs juvenile social memory and modulates hippocampal physiology
Showing 5 of 7 shared publications
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