Tiffany K. Miles
Assistant Professor
Also affiliated: Louisiana State University (2007); Arkansas Children's Hospital (2026); Arkansas Children's Nutrition Center (2026); Arkansas Children's Research Institute (2026); Carnegie Mellon University (2001)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Tiffany K. Miles investigates the impact of diet and metabolic signals on endocrine function, particularly within the pituitary gland. Her research has explored how high-fat diets influence gene expression in the anterior pituitary, with a focus on oxidative stress and cell metabolism. Miles has also studied the role of leptin signaling in the maturation of somatotropes in female mice and the effects of maternal undernutrition on offspring's metabolic responses to high-fat diets. Her work has examined the translational control of gonadotrope target mRNAs during the mouse estrous cycle and the influence of secretogranin II-derived peptides on luteinizing hormone secretion. Collaborating with researchers at the University of Arkansas for Medical Sciences, Miles has a publication record of 32 papers with 464 citations and an h-index of 7.
Metrics
- h-index: 7
- Publications: 32
- Citations: 476
Positions
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Assistant Professor publications 2019–2026University of Arkansas for Medical Sciences Institution web page
Selected Publications
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Gonadotrope remodeling in sustained low estrogen states: single-cell transcriptomic analysis reveals gonadotrope subtypes and activation of stem cell populations (2026)
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Secretogranin II–derived peptide secretoneurin differentially stimulates luteinizing hormone secretion by age and sex in ex vivo murine pituitaries (2026)
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SAT-001 Impact of VCD-induced Menopause on Gonadotrope Transcriptomics Reveals Estrogen-dependent Genes in the GnRH Signaling Pathway (2025)
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High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes (2025)
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Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice (2025)
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8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice (2024)
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8649 Ablation of Leptin Receptors in Somatotropes Impacts Transcriptomic Plasticity in the Pou1f1 Lineage of Female Pituitary Cells (2024)
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Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain (2024)
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Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism (2023)
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FRI290 Proteomic Identification Of Secretoneurin-Stimulated Proteins In Purified Mouse Gonadotropes (2023)
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THU043 Single-cell Transcriptomics Show Sex-specific Responses To A High Fat Diet, Under Thermoneutral Conditions, Pointing To Reduced Pituitary Plasticity (2023)
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Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle (2023)
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OR23-2 Mild Maternal Undernutrition Results in Transcript Regulation in the Fat of Male Offspring that Correlates with Resistance to High Fat Diet Induced Weight Gain (2022)
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410 Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge and Resistance in Male Offspring to a High Fat Diet (2022)
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Leptin: A Metabolic Signal for the Differentiation of Pituitary Cells (2021)
Collaboration Network
Top Collaborators
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- Sex differences in somatotrope response to fasting: biphasic responses in male mice
Showing 5 of 23 shared publications
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- Sex differences in somatotrope response to fasting: biphasic responses in male mice
Showing 5 of 23 shared publications
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- Sex differences in somatotrope response to fasting: biphasic responses in male mice
Showing 5 of 23 shared publications
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- Sex differences in somatotrope response to fasting: biphasic responses in male mice
Showing 5 of 20 shared publications
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- Sex differences in somatotrope response to fasting: biphasic responses in male mice
Showing 5 of 18 shared publications
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain
Showing 5 of 13 shared publications
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Sex differences in somatotrope response to fasting: biphasic responses in male mice
- Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain
- Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge that Promotes Resistance in Male Offspring to a High Fat Diet
- MON-482 Sex-Dependent Biphasic Response by Somatotropes to Fasting and Loss of Leptin Signaling
Showing 5 of 11 shared publications
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes
- Gonadotrope remodeling in sustained low estrogen states: single-cell transcriptomic analysis reveals gonadotrope subtypes and activation of stem cell populations
- FRI290 Proteomic Identification Of Secretoneurin-Stimulated Proteins In Purified Mouse Gonadotropes
Showing 5 of 8 shared publications
- Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
- Sex differences in somatotrope response to fasting: biphasic responses in male mice
- Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain
- Leptin: A Metabolic Signal for the Differentiation of Pituitary Cells
- OR24-3 Persistence of Progenitor Cell Markers Following the Selective Ablation of Musashi in Somatotropes
Showing 5 of 7 shared publications
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge that Promotes Resistance in Male Offspring to a High Fat Diet
- MON-482 Sex-Dependent Biphasic Response by Somatotropes to Fasting and Loss of Leptin Signaling
- SAT-406 Deletion of Musashi in Gonadotropes Leads to Increased GnRHR Protein Levels and Gonadotrope Dysfunction
- SAT-287 Mild Perinatal Undernutrition Results in Underweight Pups and a Premature Neonatal Leptin Surge
Showing 5 of 6 shared publications
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain
- Gonadotrope remodeling in sustained low estrogen states: single-cell transcriptomic analysis reveals gonadotrope subtypes and activation of stem cell populations
- FRI290 Proteomic Identification Of Secretoneurin-Stimulated Proteins In Purified Mouse Gonadotropes
Showing 5 of 6 shared publications
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes
- 8649 Ablation of Leptin Receptors in Somatotropes Impacts Transcriptomic Plasticity in the Pou1f1 Lineage of Female Pituitary Cells
- 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice
- Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge that Promotes Resistance in Male Offspring to a High Fat Diet
- Somatotrope Responses to Acute and Prolonged Loss of Leptin Signaling
- SAT-287 Mild Perinatal Undernutrition Results in Underweight Pups and a Premature Neonatal Leptin Surge
- 410 Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge and Resistance in Male Offspring to a High Fat Diet
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes
- 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice
- SAT-001 Impact of VCD-induced Menopause on Gonadotrope Transcriptomics Reveals Estrogen-dependent Genes in the GnRH Signaling Pathway
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- OR24-3 Persistence of Progenitor Cell Markers Following the Selective Ablation of Musashi in Somatotropes
- SAT-406 Deletion of Musashi in Gonadotropes Leads to Increased GnRHR Protein Levels and Gonadotrope Dysfunction
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