Ashley Herdman

Researcher

University of Arkansas for Medical Sciences

faculty

2 h-index 10 pubs 10 cited

Research Areas

Receptor Mechanisms and Signaling Genomics and Phylogenetic Studies Diet and metabolism studies Molecular Biology Techniques and Applications Neuroscience and Neuropharmacology Research Metabolism and Genetic Disorders Protein Structure and Dynamics

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Research Group

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OverviewAI-generated summary

Ashley Herdman's research focuses on the transcriptomics and cellular mechanisms of the anterior pituitary gland, particularly in the context of diet-induced metabolic changes and hormonal regulation in female mice. Her work investigates how factors such as high-fat diets and the ablation of leptin receptor signaling impact cell metabolism and the maturation of specific cell lineages, including somatotropes and gonadotropes. Herdman has published studies examining the effects of VCD-induced menopause on gonadotrope transcriptomics and the role of secretoneurin in modulating gonadotrope function and luteinizing hormone (LH) secretion. She has also explored proteomic identification of secretoneurin-stimulated proteins in mouse gonadotropes and developed novel designs for calcium imaging in the pituitary to understand gonadotrope network dynamics. Herdman collaborates with Gwen V. Childs, Angela K. Odle, Melanie Clair Macnicol, and Angus M. MacNicol on these investigations.

Metrics

  • h-index: 2
  • Publications: 10
  • Citations: 10

Selected Publications

  • OR13-08 Secretoneurin Modulates Gonadotrope Function Cyclically to Regulate LH Secretion (2025) DOI
  • SAT-001 Impact of VCD-induced Menopause on Gonadotrope Transcriptomics Reveals Estrogen-dependent Genes in the GnRH Signaling Pathway (2025) DOI
  • High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes (2025) DOI
  • Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice (2025) DOI
  • 8649 Ablation of Leptin Receptors in Somatotropes Impacts Transcriptomic Plasticity in the Pou1f1 Lineage of Female Pituitary Cells (2024) DOI
  • Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism (2023) DOI
  • FRI290 Proteomic Identification Of Secretoneurin-Stimulated Proteins In Purified Mouse Gonadotropes (2023) DOI

Collaborators

Researchers in the database who share publications

Gwen V. Childs University of Arkansas for Medical Sciences 8 shared publications Angela K. Odle University of Arkansas for Medical Sciences 8 shared publications Melanie Clair Macnicol University of Arkansas for Medical Sciences 8 shared publications Angus M. MacNicol University of Arkansas for Medical Sciences 8 shared publications Alex Lagasse University of Arkansas for Medical Sciences 8 shared publications Anessa Haney University of Arkansas for Medical Sciences 7 shared publications Tiffany K. Miles University of Arkansas for Medical Sciences 6 shared publications Dr. Stephanie Byrum University of Arkansas for Medical Sciences 1 shared publication

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