James Raymick
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Researcher
Also affiliated: United States Food and Drug Administration (2017–2025); Kentuckiana Pulmonary Associates (2012–2014)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
James Raymick's research centers on neurodegenerative diseases, particularly Alzheimer's disease, and the role of metals and diet in its progression. His work investigates the localization of amyloid plaques and tangles in brain tissue, utilizing techniques such as Congo Red labeling and modified K114 methods. Raymick has explored the potential link between high-fat diets and the expression of Alzheimer's-related genes in the enteric mucosa of rat models. He has also evaluated the affinity of styrylbenzene analogs for binding parenchymal plaques and tangles in human Alzheimer's patients. Furthermore, his research includes the application of proteomics to identify circulating biomarkers of neurotoxicity, offering fluidic endpoints for central nervous system toxicity in rodent models. Raymick has published 37 papers, accumulating 1,074 citations and an h-index of 18. He has collaborated with several researchers at the National Center for Toxicological Research, including Sumit Sarkar on six shared publications.
Metrics
- h-index: 18
- Publications: 37
- Citations: 1,107
Selected Publications
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A new method for visualizing cerebrovascular vessels (2026)
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Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease (2025)
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Evaluation and Characterization of Modified K114 Method to LocalizePlaques in Rodent and Plaques and Tangles in Human Brain Tissue (2024)
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Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer’s disease (2022)
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Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity (2021)
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Role of metals in Alzheimer’s disease (2021)
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In vivo demonstration of Congo Red labeled amyloid plaques via perfusion in the Alzheimer disease rat model (2021)
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Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease (2020)
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Modification of methods to use Congo-red stain to simultaneously visualize amyloid plaques and tangles in human and rodent brain tissue sections (2020)
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Impaired Amyloid Beta Clearance and Brain Microvascular Dysfunction are Present in the Tg-SwDI Mouse Model of Alzheimer’s Disease (2020)
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P4‐064: EVALUATION OF TAU NEUROPATHOLOGY AND OTHER KEY PROTEINS IN THE OLFACTORY BULB AND ITS CORRELATION WITH HIPPOCAMPUS IN HUMAN ALZHEIMER'S DISEASE (2019)
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Downregulation of 14-3-3 Proteins in Alzheimer’s Disease (2019)
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High Contrast and Resolution Labeling of Amyloid Plaques in Tissue Sections from APP-PS1 Mice and Humans with Alzheimer’s Disease with the Zinc Chelator HQ-O: Practical and Theoretical Considerations (2019)
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A Method for Sampling Rat Cerebrospinal Fluid with Minimal Blood Contamination: A Critical Tool for Biomarker Studies (2019)
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Characterization of Serum Exosomes from a Transgenic Mouse Model of Alzheimer’s Disease (2019)
Collaboration Network
Top Collaborators
- Role of metals in Alzheimer’s disease
- In vivo demonstration of Congo Red labeled amyloid plaques via perfusion in the Alzheimer disease rat model
- Evaluation and Characterization of Modified K114 Method to LocalizePlaques in Rodent and Plaques and Tangles in Human Brain Tissue
- Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer’s disease
- Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease
Showing 5 of 7 shared publications
- In vivo demonstration of Congo Red labeled amyloid plaques via perfusion in the Alzheimer disease rat model
- Evaluation and Characterization of Modified K114 Method to LocalizePlaques in Rodent and Plaques and Tangles in Human Brain Tissue
- Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer’s disease
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- In vivo demonstration of Congo Red labeled amyloid plaques via perfusion in the Alzheimer disease rat model
- Evaluation and Characterization of Modified K114 Method to LocalizePlaques in Rodent and Plaques and Tangles in Human Brain Tissue
- Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer’s disease
- Role of metals in Alzheimer’s disease
- Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer’s disease
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
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