Biography and Research Information
OverviewAI-generated summary
Reine U. Protacio's research investigates the molecular mechanisms governing meiotic recombination, focusing on how environmental factors and DNA sequence features influence its redistribution and adaptive control. Their work utilizes the model organism *Schizosaccharomyces pombe* to study the landscape of meiotic recombination with implications for evolutionary processes.
Recent publications by Protacio explore the adaptive control of the meiotic recombination landscape by DNA site-dependent hotspots and the environmental induction of rapid meiotic redistribution. Further research examines the efficiency and outcomes of CRISPR/Cas9-mediated genome editing in *S. pombe*, including the creation of novel alleles and the characterization of DNA repair templates for genome editing. Protacio's scholarship metrics include an h-index of 10, with 17 total publications and 706 total citations.
Metrics
- h-index: 10
- Publications: 17
- Citations: 706
Selected Publications
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Long multiply marked DNA repair template reveals lengths and fidelity of genome editing tracts in Schizosaccharomyces pombe (2025)
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Targeted Forward Genetics: Saturating Mutational Analyses of Specific Target Loci Within the Genome (2024)
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Agar lot-specific inhibition in the plating efficiency of yeast spores and cells (2024)
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Creating Meiotic Recombination-Regulating DNA Sites by SpEDIT in Fission Yeast Reveals Inefficiencies, Target-Site Duplications, and Ectopic Insertions (2024)
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Distance-dependent effects on CRISPR/Cas9-mediated genome editing in Schizosaccharomyces pombe compromise efficiency and create unsought alleles (2024)
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Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge (2024)
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Laboratory horror stories: Poison in the agars (2024)
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Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth (2024)
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DNA sequences and distinct mechanisms for ura4-595 and ura4-294 alleles of S. pombe (2024)
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Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution (2022)
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Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways (2022)
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Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination (2021)
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