Match tier
Confirmed
Presence
Current · Arkansas
Last published
2022
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
W
William H. Tolleson
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
High Impact
Research Chemist
Also affiliated: Qingdao University (2020); Center for Food Safety and Applied Nutrition (2006); United States Food and Drug Administration (1997–2022); University of South Carolina (1991–1994); Biochemical Society (2001); Tianjin Medical University General Hospital (2015); Professional Services Group (United States) (2012)
Faculty Researcher
32 h-index
66 pubs
2,559 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
William H. Tolleson, a Research Chemist at the National Center for Toxicological Research, has a research focus that includes the characterization of cytochrome P450 (CYP)-overexpressing HepG2 cells for evaluating drug and chemical-induced liver toxicity. His work also involves microcalorimetric investigations of protein unfolding, specifically in the context of staphylococcal enterotoxins. Tolleson has published 66 papers, accumulating over 2,500 citations and an h-index of 32, designating him as a highly cited researcher. His collaborations include work with researchers from his own institution, such as Odbert A. Triplett and Nan Mei, as well as Mark E. Hart from the University of Arkansas for Medical Sciences. Tolleson's most recent publication was in 2022, indicating his continued activity in research.
Metrics
- h-index: 32
- Publications: 66
- Citations: 2,559
Selected Publications
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Microcalorimetric Investigations of Reversible Staphylococcal Enterotoxin Unfolding (2022)
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Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity (2021)
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Long noncoding RNA LINC00844-mediated molecular network regulates expression of drug metabolizing enzymes and nuclear receptors in human liver cells (2020)
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Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells (2020)
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Regulation of cytochrome P450 expression by microRNAs and long noncoding RNAs: Epigenetic mechanisms in environmental toxicology and carcinogenesis (2019)Journal of Environmental Science and Health Part A Environmental Science and Engineering and Toxicology 4 citations OpenAlex
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MicroRNAs hsa-miR-495-3p and hsa-miR-486-5p suppress basal and rifampicin-induced expression of human sulfotransferase 2A1 (SULT2A1) by facilitating mRNA degradation (2019)
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Immunomagnetic Capture of Big Six Shiga Toxin–Producing Escherichia coli Strains in Apple Juice with Detection by Multiplex Real-Time PCR Eliminates Interference from the Food Matrix (2019)
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Regulation of cytochrome P450 expression by microRNAs and long noncoding RNAs: Epigenetic mechanisms in environmental toxicology and carcinogenesis (2019)
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MicroRNA-Dependent Gene Regulation of the Human Cytochrome P450 (2019)
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Primary and secondary pyrrolic metabolites of pyrrolizidine alkaloids form DNA adducts in human A549 cells (2018)
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Mechanistic ecotoxicology and environmental toxicology (2018)
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Mechanistic biomarkers of liver toxicity and carcinogenesis (2018)
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Mitochondrial dysfunction induced by leflunomide and its active metabolite (2018)
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Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans (2017)
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The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p (2017)
Collaboration Network
Top Collaborators
Si Chen
National Center for Toxicological Research
1 shared publication
In database
- Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity
Qiangen Wu
National Center for Toxicological Research
1 shared publication
In database
- Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity
Xilin Li
National Center for Toxicological Research
1 shared publication
In database
- Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity
Dongying Li
National Center for Toxicological Research
1 shared publication
In database
- Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity
Nan Mei
National Center for Toxicological Research
1 shared publication
In database
- Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity
Baitang Ning
National Center for Toxicological Research
1 shared publication
In database
- Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity
Montserrat Puig
United States Food and Drug Administration (US)
1 shared publication
- Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity
Zhen Ren
National Center for Toxicological Research (US)
1 shared publication
- Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity
Lei Guo
National Center for Toxicological Research
1 shared publication
In database
- Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity
Susan C. Berry
National Center for Toxicological Research
1 shared publication
In database
- Microcalorimetric Investigations of Reversible Staphylococcal Enterotoxin Unfolding
Odbert A. Triplett
National Center for Toxicological Research
1 shared publication
In database
- Microcalorimetric Investigations of Reversible Staphylococcal Enterotoxin Unfolding
Li‐Rong Yu
National Center for Toxicological Research (US)
1 shared publication
- Microcalorimetric Investigations of Reversible Staphylococcal Enterotoxin Unfolding
Mark E. Hart
National Center for Toxicological Research
1 shared publication
In database
- Microcalorimetric Investigations of Reversible Staphylococcal Enterotoxin Unfolding
Lauren S. Jackson
Center for Food Safety and Applied Nutrition (US)
1 shared publication
- Microcalorimetric Investigations of Reversible Staphylococcal Enterotoxin Unfolding
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Based on overlapping research topics
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