Laxmi Yeruva
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Adjunct Associate Professor
Also affiliated: Arkansas Children's Hospital (2011–2020); Agricultural Research Service (2022–2026); United States Department of Agriculture (2022–2026); University of Nevada, Las Vegas (2005–2009); University of Arkansas Medical Center (2017–2020); Arkansas Children's Nutrition Center (2015–2026); Radiation Oncology Centers of Nevada (2005); Arkansas Children's Research Institute (2012–2021)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Laxmi Yeruva's research investigates the role of diet and host-pathogen interactions in health and disease, with a particular focus on the gastrointestinal microbiome. Her work has explored how neonatal diets, including human milk and infant formula, influence microbial composition and metabolic pathways in infants and young mammals. This includes studies on how dietary components can shift tryptophan metabolism, impacting the production of neurotransmitters like serotonin and tryptamine. Yeruva has also examined the mechanisms of chlamydial infections, including their gastrointestinal tract involvement as a potential reservoir for persistent infections and the host immune responses, such as the induction of interferon-beta by DNA sensors like cyclic GMP-AMP synthase.
Her scholarly output includes over 112 publications with more than 2,400 citations, reflected in an h-index of 26. Yeruva's research interests extend to the effects of plant-derived compounds, such as perillyl alcohol and methyl jasmonate, on cancer cells, investigating their roles in cell cycle arrest, apoptosis, and membrane fluidity. Her work contributes to understanding complex biological systems, from microbial communities to cellular responses to therapeutic agents.
Metrics
- h-index: 26
- Publications: 113
- Citations: 2,447
Positions
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Research Leader 2021–presentUSDA-ARS Microbiome and Metabolism Research Unit ORCID
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Adjunct Associate Professor 2021–presentUAMS Pediatrics ORCID
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Associate Professor 2018–2021UAMS/ACNC/ACRI Pediatrics ORCID
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Assistant Professor 2013–2018UAMS Medical Center Pediatrics ORCID
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Instructor 2011–2013UAMS Medical Center Pediatrics ORCID
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Postdoctoral fellow 2010–2011UAMS Medical Center Pediatrics ORCID
Selected Publications
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Impact of Early Life Stress on the Composition of Gut Microbiome (2026)
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Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues (2024)
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Microbiota from human infants consuming secretors or non-secretors mothers’ milk impacts the gut and immune system in mice (2024)
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Bacterial and Fungal Adaptations in Cecum and Distal Colon of Piglets Fed With Dairy-Based Milk Formula in Comparison With Human Milk (2022)
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Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RNA but Has Persistent Levels of SARS-CoV-2-Specific IgA Antibodies (2021)
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Progression of diabetes is associated with changes in the ileal transcriptome and ileal‐colon morphology in the UC Davis Type 2 Diabetes Mellitus rat (2021)
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Milk Formula Diet Alters Bacterial and Host Protein Profile in Comparison to Human Milk Diet in Neonatal Piglet Model (2021)
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Maternal and Early-Life Factors Influence on Human Milk Composition and Infants' Gut Health (2021)
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Editorial: Impact of Early Life Nutrition on Immune System Development and Related Health Outcomes in Later Life (2021)
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Role of Human Milk Bioactives on Infants' Gut and Immune Health (2021)
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Human Milk-Fed Piglets Have a Distinct Small Intestine and Circulatory Metabolome Profile Relative to That of Milk Formula-Fed Piglets (2021)
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Reply to J Zempleni (2020)
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Neonatal Diet Impacts the Large Intestine Luminal Metabolome at Weaning and Post-Weaning in Piglets Fed Formula or Human Milk (2020)
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Early Infant Formula Feeding Impacts Urinary Metabolite Profile at 3 Months of Age (2020)
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Perspective: The Role of Human Breast-Milk Extracellular Vesicles in Child Health and Disease (2020)
Collaboration Network
Top Collaborators
- Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
Showing 5 of 21 shared publications
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Xenometabolite signatures in the UC Davis type 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with microbe-derived metabolites
Showing 5 of 17 shared publications
- Hidden in Plain Sight: Chlamydial Gastrointestinal Infection and Its Relevance to Persistence in Human Genital Infection
- Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection
- Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Differential Susceptibilities to Azithromycin Treatment of Chlamydial Infection in the Gastrointestinal Tract and Cervix
Showing 5 of 13 shared publications
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Neonatal Diet Impacts Bioregional Microbiota Composition in Piglets Fed Human Breast Milk or Infant Formula
Showing 5 of 12 shared publications
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Neonatal Diet Impacts Bioregional Microbiota Composition in Piglets Fed Human Breast Milk or Infant Formula
Showing 5 of 11 shared publications
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Human Breast-Milk Feeding Enhances the Humoral and Cell-Mediated Immune Response in Neonatal Piglets
Showing 5 of 11 shared publications
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Neonatal Diet Impacts Bioregional Microbiota Composition in Piglets Fed Human Breast Milk or Infant Formula
- Xenometabolite signatures in the UC Davis type 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with microbe-derived metabolites
Showing 5 of 11 shared publications
- Role of Human Milk Bioactives on Infants' Gut and Immune Health
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Perspective: The Role of Human Breast-Milk Extracellular Vesicles in Child Health and Disease
- Formula Diet Alters the Ileal Metagenome and Transcriptome at Weaning and during the Postweaning Period in a Porcine Model
- Human Milk-Fed Piglets Have a Distinct Small Intestine and Circulatory Metabolome Profile Relative to That of Milk Formula-Fed Piglets
Showing 5 of 10 shared publications
- Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection
- Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Differential Susceptibilities to Azithromycin Treatment of Chlamydial Infection in the Gastrointestinal Tract and Cervix
- Role of bacterial infections in extracellular vesicles release and impact on immune response
Showing 5 of 9 shared publications
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Xenometabolite signatures in the UC Davis type 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with microbe-derived metabolites
- Progression of diabetes is associated with changes in the ileal transcriptome and ileal‐colon morphology in the UC Davis Type 2 Diabetes Mellitus rat
- Human Milk-Fed Piglets Have a Distinct Small Intestine and Circulatory Metabolome Profile Relative to That of Milk Formula-Fed Piglets
Showing 5 of 9 shared publications
- Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Human Breast-Milk Feeding Enhances the Humoral and Cell-Mediated Immune Response in Neonatal Piglets
- Formula Diet Alters the Ileal Metagenome and Transcriptome at Weaning and during the Postweaning Period in a Porcine Model
Showing 5 of 8 shared publications
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Infant Formula Feeding Increases Hepatic Cholesterol 7α Hydroxylase (CYP7A1) Expression and Fecal Bile Acid Loss in Neonatal Piglets
- Infant Formula Feeding Changes the Proliferative Status in Piglet Neonatal Mammary Glands Independently of Estrogen Signaling
- MicroRNA profiles were altered in neonatal piglet mammary glands following postnatal infant formula feeding
- Male testicular development is affected by estrogens but not altered in neonatal piglets receiving soy infant formula
Showing 5 of 8 shared publications
- Role of Human Milk Bioactives on Infants' Gut and Immune Health
- Human Milk-Fed Piglets Have a Distinct Small Intestine and Circulatory Metabolome Profile Relative to That of Milk Formula-Fed Piglets
- Neonatal Diet Impacts the Large Intestine Luminal Metabolome at Weaning and Post-Weaning in Piglets Fed Formula or Human Milk
- Early Infant Formula Feeding Impacts Urinary Metabolite Profile at 3 Months of Age
- Bacterial and Fungal Adaptations in Cecum and Distal Colon of Piglets Fed With Dairy-Based Milk Formula in Comparison With Human Milk
Showing 5 of 7 shared publications
- Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Human Breast-Milk Feeding Enhances the Humoral and Cell-Mediated Immune Response in Neonatal Piglets
- Infant Formula Feeding Increases Hepatic Cholesterol 7α Hydroxylase (CYP7A1) Expression and Fecal Bile Acid Loss in Neonatal Piglets
- Erratum for Yeruva et al., Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection
Showing 5 of 6 shared publications
- Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs
- Infant Formula Feeding Increases Hepatic Cholesterol 7α Hydroxylase (CYP7A1) Expression and Fecal Bile Acid Loss in Neonatal Piglets
- Infant Formula Feeding Changes the Proliferative Status in Piglet Neonatal Mammary Glands Independently of Estrogen Signaling
- MicroRNA profiles were altered in neonatal piglet mammary glands following postnatal infant formula feeding
- Programming Effects of Infant Diet on Cholesterol/Bile Acid Synthesis and Absorption in Piglets
Showing 5 of 6 shared publications
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