Match tier
Likely match
Presence
Current · Arkansas
Last published
2024
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
J
Jun Gao
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Instructor
Also affiliated: University of Kansas (1996); Dalian Medical University (2018); Chinese Academy of Medical Sciences & Peking Union Medical College (2005); Ministry of Ecology and Environment (2024); Huai'an University (2021–2022); Nanjing Institute of Environmental Sciences (2024); Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences (2005)
15 h-index
35 pubs
724 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jun Gao's research focuses on the roles of G-quadruplex DNA structures and associated proteins in cellular processes, particularly in yeast and human systems. His work investigates how these structures influence genome stability, stress responses, and gene regulation. Gao has published on the accumulation of G-quadruplex DNA in the cytoplasm during oxidative stress and its participation in stress granule assembly. He has also explored the function of yeast Sub1 and its human homolog PC4 as G-quadruplex binding proteins that suppress genome instability. Further research examines the interaction of DEAD-box RNA helicases with G-quadruplex nucleic acids and their destabilization of G-quadruplex RNA. Gao also has experience with CRISPR-based proteomic analysis and allele replacement techniques in yeast.
Metrics
- h-index: 15
- Publications: 35
- Citations: 724
Positions
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Instructor publications 2004–2024University of Arkansas for Medical Sciences Institution web page
Selected Publications
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Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge (2024)
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Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth (2024)
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Pif1 Helicase Mediates Remodeling of Protein-Nucleic Acid Complexes by Promoting Dissociation of Sub1 from G-Quadruplex DNA and Cdc13 from G-Rich Single-Stranded DNA (2023)
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Hepatitis C virus nonstructural protein NS3 unfolds viral G-quadruplex RNA structures (2022)
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RNA helicases required for viral propagation in humans (2021)
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A structural feature of Dda helicase which enhances displacement of streptavidin and trp repressor from DNA (2021)
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G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p (2021)
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G-Quadruplex loops regulate PARP-1 enzymatic activation (2020)
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DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA (2019)
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A fast approach to detect gene–gene synergy (2017)
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A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4 (2017)
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Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA (2017)
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The Structural Recognition of G‐quadruplex DNA by PC4: How Does a ssDNA Binding Protein Decide? (2016)
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Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA (2015)
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Binding of the transcription factor Atf1 to promoters serves as a barrier to phase nucleosome arrays and avoid cryptic transcription (2014)
Collaboration Network
Top Collaborators
Kevin D. Raney
University of Arkansas Medical Center
14 shared publications
In database
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- G-Quadruplex loops regulate PARP-1 enzymatic activation
- Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA
- Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA
- DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA
Showing 5 of 14 shared publications
Alicia K. Byrd
University of Arkansas Medical Center
12 shared publications
In database
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- G-Quadruplex loops regulate PARP-1 enzymatic activation
- Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA
- DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA
- A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4
Showing 5 of 12 shared publications
Wayne P. Wahls
University of Arkansas for Medical Sciences
11 shared publications
In database
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Binding of the transcription factor Atf1 to promoters serves as a barrier to phase nucleosome arrays and avoid cryptic transcription
- Purification, folding, and characterization of Rec12 (Spo11) meiotic recombinase of fission yeast
- Phosphorylation-Independent Regulation of Atf1-Promoted Meiotic Recombination by Stress-Activated, p38 Kinase Spc1 of Fission Yeast
Showing 5 of 11 shared publications
Mari K. Davidson
University of Arkansas for Medical Sciences
7 shared publications
In database
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- Purification, folding, and characterization of Rec12 (Spo11) meiotic recombinase of fission yeast
- Phosphorylation-Independent Regulation of Atf1-Promoted Meiotic Recombination by Stress-Activated, p38 Kinase Spc1 of Fission Yeast
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- Regulation of meiotic recombination by a multifunctional ATF/CREB protein
Showing 5 of 7 shared publications
John C. Marecki
University of Arkansas for Medical Sciences
7 shared publications
In database
- G-Quadruplex loops regulate PARP-1 enzymatic activation
- DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA
- RNA helicases required for viral propagation in humans
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
Showing 5 of 7 shared publications
Shubeena Chib
University of Arkansas for Medical Sciences (US)
6 shared publications
- Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA
- Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA
- DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA
- A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4
- Pif1 Helicase Mediates Remodeling of Protein-Nucleic Acid Complexes by Promoting Dissociation of Sub1 from G-Quadruplex DNA and Cdc13 from G-Rich Single-Stranded DNA
Showing 5 of 6 shared publications
Wezley C. Griffin
University of Arkansas for Medical Sciences (US)
5 shared publications
- Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA
- Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA
- A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4
- Pif1 Helicase Mediates Remodeling of Protein-Nucleic Acid Complexes by Promoting Dissociation of Sub1 from G-Quadruplex DNA and Cdc13 from G-Rich Single-Stranded DNA
- The Structural Recognition of G‐quadruplex DNA by PC4: How Does a ssDNA Binding Protein Decide?
Reine U. Protacio
University of Arkansas for Medical Sciences
4 shared publications
In database
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge
- Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth
- A stress‐activated, p38 MAPK‐ATF/CREB pathway regulates the post‐transcriptional decay of target mRNAs
Jacy L. Wagnon
University of Arkansas for Medical Sciences (US)
3 shared publications
- Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- A stress‐activated, p38 MAPK‐ATF/CREB pathway regulates the post‐transcriptional decay of target mRNAs
Samuel G. Mackintosh
University of Arkansas for Medical Sciences
3 shared publications
In database
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA
- DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA
A. Edwards
University of Arkansas for Medical Sciences
3 shared publications
In database
- G-Quadruplex loops regulate PARP-1 enzymatic activation
- DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
Galina Glazko
University of Arkansas for Medical Sciences
2 shared publications
In database
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- A stress‐activated, p38 MAPK‐ATF/CREB pathway regulates the post‐transcriptional decay of target mRNAs
Marjorie L. Beggs
University of Arkansas for Medical Sciences (US)
2 shared publications
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- A stress‐activated, p38 MAPK‐ATF/CREB pathway regulates the post‐transcriptional decay of target mRNAs
Vinay Raj
University of Arkansas for Medical Sciences
2 shared publications
In database
- A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs
- A stress‐activated, p38 MAPK‐ATF/CREB pathway regulates the post‐transcriptional decay of target mRNAs
Zachary J. Waldrip
University of Arkansas for Medical Sciences
2 shared publications
In database
- A CRISPR-based approach for proteomic analysis of a single genomic locus
- DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA
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