Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-16
S
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Sharmin Khan's research focuses on the molecular mechanisms underlying bone destruction in the context of multiple myeloma and other cancers. Her work investigates signaling pathways that contribute to the tumor microenvironment and influence bone cell behavior. Recent publications explore the role of NOTCH3-CXCL12 signaling in promoting chemoresistance in multiple myeloma and the function of senescent osteocytes in driving bone destruction in breast cancer metastasis. Khan also studies therapeutic strategies, including targeting Notch inhibitors and sclerostin inhibition, to mitigate tumor growth and preserve bone health. Her research has been supported by grants from various agencies, and she collaborates with researchers at the University of Arkansas for Medical Sciences, including Hayley M. Sabol, Aric Anloague, Olivia Reyes‐Castro, and Japneet Kaur. Khan has published 95 papers and has an h-index of 12, with 675 citations.
Metrics
- h-index: 12
- Publications: 95
- Citations: 675
Selected Publications
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells (2026)
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Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition (2025)
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Abstract 5099: Notch inhibition as a therapeutic approach to eliminate dormant cancer cells in multiple myeloma (2025)
Collaboration Network
Top Collaborators
Hayley M. Sabol
University of Arkansas for Medical Sciences
13 shared publications
In database
- Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma
- A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
Showing 5 of 13 shared publications
Jesús Delgado‐Calle
University of Arkansas for Medical Sciences
12 shared publications
In database
- Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma
- A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
Showing 5 of 12 shared publications
Aric Anloague
University of Arkansas for Medical Sciences
11 shared publications
In database
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma
- A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
Showing 5 of 11 shared publications
Frank H. Ebetino
BioVinc (United States) (US)
8 shared publications
- Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Data from Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 8 shared publications
Manish Adhikari
University of Arkansas for Medical Sciences (US)
6 shared publications
- Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Abstract 5675: Pathological crosstalk between osteocytes and breast cancer cells in bone metastasis
Showing 5 of 6 shared publications
Carolina Schinke
University of Arkansas for Medical Sciences
6 shared publications
In database
- A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma
- A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 6 shared publications
Bethany C. Paxton
University of Arkansas for Medical Sciences
6 shared publications
In database
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Showing 5 of 6 shared publications
Japneet Kaur
Winthrop Rockefeller Foundation
5 shared publications
In database
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma
- A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
C. Lowry Barnes
University of Arkansas for Medical Sciences
5 shared publications
In database
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma
- A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
Elena Ambrogini
University of Arkansas for Medical Sciences
5 shared publications
In database
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma
- A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
Corey O. Montgomery
University of Arkansas for Medical Sciences
5 shared publications
In database
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Cody Ashby
University of Arkansas for Medical Sciences
5 shared publications
In database
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Additional file 1 of Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
- Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells
Noriyoshi Kurihara
Indiana University – Purdue University Indianapolis (US)
4 shared publications
- Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Data from Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity
Intawat Nookaew
University of Arkansas for Medical Sciences
4 shared publications
In database
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
Marta Diaz‐delCastillo
Aarhus University (DK)
4 shared publications
- Single-Cell Transcriptomic Analysis Identifies Senescent Osteocytes That Trigger Bone Destruction in Breast Cancer Metastasis
- A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma
- Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis
- Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition
Similar Researchers
Based on overlapping research topics
Jesús Delgado‐Calle
University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments
Bone Metabolism and Diseases
Cancer Cells and Metastasis
Aric Anloague
University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments
Bone Metabolism and Diseases
Cancer Cells and Metastasis
Hayley M. Sabol
University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments
Bone Metabolism and Diseases
Disease Models, Animal
Elena Ambrogini
University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments
Bone Metabolism and Diseases
Cancer Cells and Metastasis
Bethany C. Paxton
University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments
Cancer Cells and Metastasis
Disease Models, Animal
Delgado-Calle Jesus
University of Arkansas for Medical Sciences
Multiple Myeloma Research and Treatments
Cancer Cells and Metastasis
Disease Models, Animal