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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Tiffany K. Miles

Researcher

Also affiliated: Louisiana State University (2007); Arkansas Children's Hospital (2026); Arkansas Children's Nutrition Center (2026); Carnegie Mellon University (2001)

Faculty Researcher

7 h-index 32 pubs 468 cited

  • Animals
  • Mice
  • Female
  • Diet, High-Fat
  • Pituitary Gland
  • Male
  • Somatotrophs
  • Receptors, Leptin
  • Mice, Inbred C57BL
  • Gonadotrophs
  • Signal Transduction
  • Leptin
  • Aging
  • Obesity
  • Weight Gain

Biography and Research Information

OverviewAI-generated summary

Tiffany K. Miles investigates the impact of diet and metabolic signals on endocrine function, particularly within the pituitary gland. Her research has explored how high-fat diets influence gene expression in the anterior pituitary, with a focus on oxidative stress and cell metabolism. Miles has also studied the role of leptin signaling in the maturation of somatotropes in female mice and the effects of maternal undernutrition on offspring's metabolic responses to high-fat diets. Her work has examined the translational control of gonadotrope target mRNAs during the mouse estrous cycle and the influence of secretogranin II-derived peptides on luteinizing hormone secretion. Collaborating with researchers at the University of Arkansas for Medical Sciences, Miles has a publication record of 32 papers with 464 citations and an h-index of 7.

Metrics

  • h-index: 7
  • Publications: 32
  • Citations: 468

Selected Publications

  • Gonadotrope remodeling in sustained low estrogen states: single-cell transcriptomic analysis reveals gonadotrope subtypes and activation of stem cell populations (2026)
    Biology of Reproduction 1 citation DOI OpenAlex
  • Secretogranin II–derived peptide secretoneurin differentially stimulates luteinizing hormone secretion by age and sex in ex vivo murine pituitaries (2026)
    Biology of Reproduction DOI OpenAlex
  • SAT-001 Impact of VCD-induced Menopause on Gonadotrope Transcriptomics Reveals Estrogen-dependent Genes in the GnRH Signaling Pathway (2025)
    Journal of the Endocrine Society DOI OpenAlex
  • High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes (2025)
    Frontiers in Endocrinology 1 citation DOI OpenAlex
  • Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice (2025)
    Endocrinology 5 citations DOI OpenAlex
  • 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice (2024)
    Journal of the Endocrine Society DOI OpenAlex
  • 8649 Ablation of Leptin Receptors in Somatotropes Impacts Transcriptomic Plasticity in the Pou1f1 Lineage of Female Pituitary Cells (2024)
    Journal of the Endocrine Society DOI OpenAlex
  • Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain (2024)
    Frontiers in Endocrinology 4 citations DOI OpenAlex
  • Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism (2023)
    Endocrinology 12 citations DOI OpenAlex
  • FRI290 Proteomic Identification Of Secretoneurin-Stimulated Proteins In Purified Mouse Gonadotropes (2023)
    Journal of the Endocrine Society DOI OpenAlex
  • THU043 Single-cell Transcriptomics Show Sex-specific Responses To A High Fat Diet, Under Thermoneutral Conditions, Pointing To Reduced Pituitary Plasticity (2023)
    Journal of the Endocrine Society DOI OpenAlex
  • Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle (2023)
    Endocrinology 10 citations DOI OpenAlex
  • OR23-2 Mild Maternal Undernutrition Results in Transcript Regulation in the Fat of Male Offspring that Correlates with Resistance to High Fat Diet Induced Weight Gain (2022)
    Journal of the Endocrine Society DOI OpenAlex
  • 410 Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge and Resistance in Male Offspring to a High Fat Diet (2022)
    Journal of Clinical and Translational Science DOI OpenAlex
  • Leptin: A Metabolic Signal for the Differentiation of Pituitary Cells (2021)
    IntechOpen eBooks 1 citation DOI OpenAlex

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Collaboration Network

33 Collaborators 8 Institutions 2 Countries

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