Match tier Listed
Presence Formerly Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-16

Francesca V. LoBianco

Researcher

Formerly Arkansas Affiliated with University of Arkansas, UAMS through 2023; recent publications list Illinois College, University of Illinois Chicago.

Faculty Researcher

5 h-index 14 pubs 86 cited

  • Sirtuin 3
  • Cell Compartmentation
  • Animals
  • Animals, Wild
  • Antioxidants
  • Cognition
  • Disease Models, Animal
  • Female
  • Hippocampus
  • Male
  • Mitochondria
  • Superoxide Dismutase
  • Oxidative Stress
  • Mice
  • Data Analysis

Biography and Research Information

OverviewAI-generated summary

Francesca V. LoBianco's research investigates the role of Sirtuin 3 (Sirt3) in cellular function, particularly within the hippocampus. Her work has explored the effects of Sirt3 on mitochondrial function, specifically the activity of manganese superoxide dismutase (MnSOD). Studies have examined these effects in aged murine models, assessing impacts on physiology and cognition. LoBianco's publications also address mechanisms of drug-induced hepatotoxicity, including the role of cytochrome P450 3A4 in the metabolism of sorafenib and lapatinib. Additionally, her research has touched upon the induction of ferroptosis in hepatocellular carcinoma cells by parthenolide, through thiol oxidation. She has published 14 papers with 86 citations and an h-index of 5. LoBianco collaborates with researchers from the University of Arkansas at Fayetteville, including Nükhet Aykin‐Burns and Kimberly J. Krager.

Metrics

  • h-index: 5
  • Publications: 14
  • Citations: 86

Selected Publications

  • The Role of Cytochrome P450 3A4-Mediated Metabolism in Sorafenib and Lapatinib Hepatotoxicity (2023)
    Livers 12 citations DOI OpenAlex
  • Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model (2023)
    Behavioural Brain Research 9 citations DOI OpenAlex
  • Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, And Cognition in an Aged Murine Model (2022)
    SSRN Electronic Journal DOI OpenAlex
  • Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model (2022)
    SSRN Electronic Journal DOI OpenAlex
  • Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells (2022)
    Frontiers in Toxicology 19 citations DOI OpenAlex
  • Overcoming the Restricted Therapy Options and Monitoring Challenges in Metastatic Breast Cancer (2021)
    Toxicology Letters DOI OpenAlex
  • Abstract No. 584 Parthenolide induces thiol oxidation inducing ferroptosis in human hepatocellular carcinoma cells (2021)
    Journal of Vascular and Interventional Radiology DOI OpenAlex
  • Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein (2020)
    Journal of Visualized Experiments DOI OpenAlex
  • Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation (2020)
    Oncotarget 34 citations DOI OpenAlex
  • Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein (2020)
    Journal of Visualized Experiments 1 citation DOI OpenAlex
  • The Role of Sirtuin 3 in Radiation-Induced Long-Term Persistent Liver Injury (2020)
    Antioxidants 16 citations DOI OpenAlex
  • Abstract No. 428 Parthenolide induces thiol oxidation-mediated cytotoxicity in human and rat hepatocellular carcinoma cell lines (2020)
    Journal of Vascular and Interventional Radiology DOI OpenAlex
  • 03:27 PM Abstract No. 221 Porcine and human hepatocellular carcinoma cell lines present similar drug-metabolizing enzyme expression levels and comparable sorafenib and doxorubicin cytotoxic responses (2019)
    Journal of Vascular and Interventional Radiology DOI OpenAlex

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Collaboration Network

19 Collaborators 4 Institutions 2 Countries

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