Francesca V. LoBianco

Researcher

Last publication 2023 Last refreshed 2026-04-01

faculty

5 h-index 14 pubs 86 cited

Biography and Research Information

OverviewAI-generated summary

Francesca V. LoBianco's research investigates the role of Sirtuin 3 (Sirt3) in cellular function, particularly within the hippocampus. Her work has explored the effects of Sirt3 on mitochondrial function, specifically the activity of manganese superoxide dismutase (MnSOD). Studies have examined these effects in aged murine models, assessing impacts on physiology and cognition. LoBianco's publications also address mechanisms of drug-induced hepatotoxicity, including the role of cytochrome P450 3A4 in the metabolism of sorafenib and lapatinib. Additionally, her research has touched upon the induction of ferroptosis in hepatocellular carcinoma cells by parthenolide, through thiol oxidation. She has published 14 papers with 86 citations and an h-index of 5. LoBianco collaborates with researchers from the University of Arkansas at Fayetteville, including Nükhet Aykin‐Burns and Kimberly J. Krager.

Metrics

  • h-index: 5
  • Publications: 14
  • Citations: 86

Selected Publications

  • The Role of Cytochrome P450 3A4-Mediated Metabolism in Sorafenib and Lapatinib Hepatotoxicity (2023)
    10 citations DOI OpenAlex
  • Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model (2023)
    9 citations DOI OpenAlex
  • Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, And Cognition in an Aged Murine Model (2022)
  • Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model (2022)
  • Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells (2022)
    17 citations DOI OpenAlex
  • Overcoming the Restricted Therapy Options and Monitoring Challenges in Metastatic Breast Cancer (2021)
  • Abstract No. 584 Parthenolide induces thiol oxidation inducing ferroptosis in human hepatocellular carcinoma cells (2021)

View all publications on OpenAlex →

Collaboration Network

19 Collaborators 4 Institutions 2 Countries

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