Biography and Research Information
OverviewAI-generated summary
Francesca V. LoBianco's research investigates the role of Sirtuin 3 (Sirt3) in cellular function, particularly within the hippocampus. Her work has explored the effects of Sirt3 on mitochondrial function, specifically the activity of manganese superoxide dismutase (MnSOD). Studies have examined these effects in aged murine models, assessing impacts on physiology and cognition. LoBianco's publications also address mechanisms of drug-induced hepatotoxicity, including the role of cytochrome P450 3A4 in the metabolism of sorafenib and lapatinib. Additionally, her research has touched upon the induction of ferroptosis in hepatocellular carcinoma cells by parthenolide, through thiol oxidation. She has published 14 papers with 86 citations and an h-index of 5. LoBianco collaborates with researchers from the University of Arkansas at Fayetteville, including Nükhet Aykin‐Burns and Kimberly J. Krager.
Metrics
- h-index: 5
- Publications: 14
- Citations: 86
Selected Publications
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The Role of Cytochrome P450 3A4-Mediated Metabolism in Sorafenib and Lapatinib Hepatotoxicity (2023)
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Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model (2023)
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Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, And Cognition in an Aged Murine Model (2022)
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Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model (2022)
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Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells (2022)
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Overcoming the Restricted Therapy Options and Monitoring Challenges in Metastatic Breast Cancer (2021)
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Abstract No. 584 Parthenolide induces thiol oxidation inducing ferroptosis in human hepatocellular carcinoma cells (2021)
Collaboration Network
Top Collaborators
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- The Role of Cytochrome P450 3A4-Mediated Metabolism in Sorafenib and Lapatinib Hepatotoxicity
- Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model
- Abstract No. 584 Parthenolide induces thiol oxidation inducing ferroptosis in human hepatocellular carcinoma cells
- Overcoming the Restricted Therapy Options and Monitoring Challenges in Metastatic Breast Cancer
Showing 5 of 7 shared publications
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model
- Abstract No. 584 Parthenolide induces thiol oxidation inducing ferroptosis in human hepatocellular carcinoma cells
- Overcoming the Restricted Therapy Options and Monitoring Challenges in Metastatic Breast Cancer
- Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model
Showing 5 of 6 shared publications
- Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model
- Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model
- Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, And Cognition in an Aged Murine Model
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model
- Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model
- Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, And Cognition in an Aged Murine Model
- Abstract No. 584 Parthenolide induces thiol oxidation inducing ferroptosis in human hepatocellular carcinoma cells
- Overcoming the Restricted Therapy Options and Monitoring Challenges in Metastatic Breast Cancer
- Overcoming the Restricted Therapy Options and Monitoring Challenges in Metastatic Breast Cancer
- Overcoming the Restricted Therapy Options and Monitoring Challenges in Metastatic Breast Cancer
- Overcoming the Restricted Therapy Options and Monitoring Challenges in Metastatic Breast Cancer
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
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