Biography and Research Information
OverviewAI-generated summary
Hannah Shibo Xu studies the effects of environmental stressors on biological systems, with a particular focus on the gut microbiome and its influence on reproduction, metabolism, and behavior. Her research investigates the toxicity of various chemical compounds, including bisphenol analogues and nanocellulose, across multiple species, including mice and chickens. Xu's work explores how these exposures, often in conjunction with dietary factors like a Western diet, can alter physiological processes such as folliculogenesis and glucose homeostasis. She also examines the role of the gut-brain axis in modulating behaviors, particularly in the context of chronic exposure to substances like nanocellulose. Additionally, her research extends to the potential of dietary supplements, such as lemon and glycerin, to beneficially regulate blood glucose levels through gut microbiota modulation. Xu has also investigated mutation accumulation in human cell lines following exposure to genotoxic carcinogens.
Metrics
- h-index: 6
- Publications: 21
- Citations: 185
Selected Publications
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Adjusting the Preincubation Conditions to Enhance the Ames Test for Detecting the Mutagenicity of <i>N</i> ‐Nitrosamines (2026)
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Mutagenicity of EAT-positive NDSRIs in HepaRG spheroids (2026)
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Mutation accumulation following extended exposure of human HepaRG cells to a genotoxic carcinogen (2025)
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Genotoxicity evaluation of ten nitrosamine drug substance-related impurities using 2D and 3D HepaRG cell models (2025)
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Development of a TK6-derived cell line expressing four human cytochrome P450s for genotoxicity testing (2025)
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Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of 4 small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities (2025)
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Evaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencing (2024)
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Application of HepaRG cells for genotoxicity assessment: a review (2024)
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Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models (2023)
Collaboration Network
Top Collaborators
Tai L. Guo
University of Georgia (US)
6 shared publications
- Toxicity of bisphenol analogues on the reproductive, nervous, and immune systems, and their relationships to gut microbiome and metabolism: insights from a multi-species comparison
- Modulation of folliculogenesis in adult laying chickens by bisphenol A and bisphenol S: Perspectives on ovarian morphology and gene expression
- Chronic exposure to nanocellulose altered depression-related behaviors in mice on a western diet: The role of immune modulation and the gut microbiome
- Dietary Supplements and the Gut–Brain Axis: A Focus on Lemon, Glycerin, and Their Combinations
- Nanocellulose dysregulated glucose homeostasis in female mice on a Western diet: The role of gut microbiome
Showing 5 of 6 shared publications
Callie M. McDonough
University of Georgia (US)
3 shared publications
- Toxicity of bisphenol analogues on the reproductive, nervous, and immune systems, and their relationships to gut microbiome and metabolism: insights from a multi-species comparison
- Chronic exposure to nanocellulose altered depression-related behaviors in mice on a western diet: The role of immune modulation and the gut microbiome
- Combining Lemon and Glycerin may Beneficially Regulate Blood Glucose Levels by Modulating Gut Microbiota in Non-obese Diabetic Mice
Fatma Eldefrawy
Institute of Biomedical Science (GB)
2 shared publications
- Modulation of folliculogenesis in adult laying chickens by bisphenol A and bisphenol S: Perspectives on ovarian morphology and gene expression
- Nanocellulose dysregulated glucose homeostasis in female mice on a Western diet: The role of gut microbiome
Yingjia Chen
Institute of Biomedical Science (GB)
2 shared publications
- Chronic exposure to nanocellulose altered depression-related behaviors in mice on a western diet: The role of immune modulation and the gut microbiome
- Nanocellulose dysregulated glucose homeostasis in female mice on a Western diet: The role of gut microbiome
Avani Patel
University of Georgia (US)
2 shared publications
- Chronic exposure to nanocellulose altered depression-related behaviors in mice on a western diet: The role of immune modulation and the gut microbiome
- Combining Lemon and Glycerin may Beneficially Regulate Blood Glucose Levels by Modulating Gut Microbiota in Non-obese Diabetic Mice
Elizabeth A. Pusch
University of Georgia (US)
1 shared publication
- Modulation of folliculogenesis in adult laying chickens by bisphenol A and bisphenol S: Perspectives on ovarian morphology and gene expression
Ashraf Karkoura
Alexandria University (EG)
1 shared publication
- Modulation of folliculogenesis in adult laying chickens by bisphenol A and bisphenol S: Perspectives on ovarian morphology and gene expression
Mohamed Alsafy
Alexandria University (EG)
1 shared publication
- Modulation of folliculogenesis in adult laying chickens by bisphenol A and bisphenol S: Perspectives on ovarian morphology and gene expression
Samir A.A. El‐Gendy
Alexandria University (EG)
1 shared publication
- Modulation of folliculogenesis in adult laying chickens by bisphenol A and bisphenol S: Perspectives on ovarian morphology and gene expression
Susan M. Williams
University of Georgia (US)
1 shared publication
- Modulation of folliculogenesis in adult laying chickens by bisphenol A and bisphenol S: Perspectives on ovarian morphology and gene expression
Kristen J. Navara
University of Georgia (US)
1 shared publication
- Modulation of folliculogenesis in adult laying chickens by bisphenol A and bisphenol S: Perspectives on ovarian morphology and gene expression
Zhiping Wang
University of Georgia (US)
1 shared publication
- Chronic exposure to nanocellulose altered depression-related behaviors in mice on a western diet: The role of immune modulation and the gut microbiome
Quincy Teng
University of Georgia (US)
1 shared publication
- Combining Lemon and Glycerin may Beneficially Regulate Blood Glucose Levels by Modulating Gut Microbiota in Non-obese Diabetic Mice
J. Martín Navarro
University of Georgia (US)
1 shared publication
- Dietary Supplements and the Gut–Brain Axis: A Focus on Lemon, Glycerin, and Their Combinations
Manuel Ismael Laurencio Luna
University of Georgia (US)
1 shared publication
- Dietary Supplements and the Gut–Brain Axis: A Focus on Lemon, Glycerin, and Their Combinations
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