James C. Fuscoe

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

High Impact

Researcher

NCTR primary UAMS

Also affiliated: University of Vermont (1993); Lawrence Livermore National Laboratory (1985–2008); Oak Ridge National Laboratory (1978–1982); Arkansas Children's Hospital (2009); Environmental Protection Agency (1993–2003); Research Triangle Park Foundation (1992–2003); St. Jude Children's Research Hospital (1998); United States Food and Drug Administration (2003–2026); Center for Drug Evaluation and Research (2020); Howard Hughes Medical Institute (1983–1984); University of Connecticut (1991); Illumina (United States) (2014); Baylor College of Medicine (1982–1984); American Association of Colleges of Pharmacy (1998); Center for Environmental Health (1991); Centre National pour la Recherche Scientifique et Technique (CNRST) (1995); National Institute of Environmental Health Sciences (1992–1994); Cell Biotech (South Korea) (1983); Biolog (United States) (1983); Food and Drug Administration (2004); Genomics (United Kingdom) (2004); University of Tennessee at Knoxville (1978–1998); Louisiana State University Health Sciences Center New Orleans (2008); Institut Curie (1995); Jefferson College (2009)

Faculty Researcher

47 h-index 168 pubs 13,517 cited

Research Areas

Biomedical Subjects

Links

Lab Website

OverviewAI-generated summary

James C. Fuscoe's research centers on understanding and identifying biomarkers for drug-induced toxicities, particularly cardiotoxicity. His work has investigated the mechanisms behind doxorubicin-induced cardiotoxicity, exploring its delayed-onset and subclinical manifestations in preclinical models.

His recent publications highlight the potential of microRNA-34a-5p as an early circulating biomarker for chronic cardiotoxicity. Fuscoe has also examined the role of the apelin-APJ pathway in sex-related differential cardiotoxicity caused by doxorubicin. Furthermore, his research includes studies on predictive risk factors for myocardial injury in pediatric patients treated with anthracyclines.

Fuscoe holds a high-impact researcher designation, evidenced by his h-index of 47 and over 13,000 citations across 168 publications. He collaborates with researchers at the National Center for Toxicological Research and the University of Arkansas for Medical Sciences, maintaining an active laboratory website.

Metrics

h-index: 47
Publications: 168
Citations: 13,517

Selected Publications

Correction: Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study (2026)

Cardiovascular Toxicology DOI OpenAlex
Exploring Predictive Risk Factors for Myocardial Injury in Children Treated with Anthracyclines: A Pilot Study (2025)

Cardiovascular Toxicology DOI OpenAlex
Potential role of the apelin‐APJ pathway in sex‐related differential cardiotoxicity induced by doxorubicin in mice (2022)

Journal of Applied Toxicology 7 citations DOI OpenAlex
MicroRNA‐34a‐5p as a promising early circulating preclinical biomarker of doxorubicin‐induced chronic cardiotoxicity (2022)

Journal of Applied Toxicology 14 citations DOI OpenAlex
Doxorubicin‐induced delayed‐onset subclinical cardiotoxicity in mice (2021)

Journal of Applied Toxicology 15 citations DOI OpenAlex
Simultaneous Quantification of t(14;18) and HPRT Exon 2/3 Deletions in Human Lymphocytes (2020)

Methods in molecular biology 3 citations DOI OpenAlex
A comprehensive rat transcriptome built from large scale RNA-seq-based annotation (2020)

Nucleic Acids Research 32 citations DOI OpenAlex
Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism (2020)

Drug Metabolism and Disposition 21 citations DOI OpenAlex
Rebuttal to the comments by Dr. Yan Xu on the article “Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone” (2019)

Reproductive Toxicology DOI OpenAlex
Candidate early predictive plasma protein markers of doxorubicin-induced chronic cardiotoxicity in B6C3F1 mice (2018)

Toxicology and Applied Pharmacology 23 citations DOI OpenAlex
Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone (2018)

Reproductive Toxicology 10 citations DOI OpenAlex
Transcriptomics analysis of early embryonic stem cell differentiation under osteoblast culture conditions: Applications for detection of developmental toxicity (2017)

Reproductive Toxicology 5 citations DOI OpenAlex
Sex and age differences in the expression of liver microRNAs during the life span of F344 rats (2017)

Biology of Sex Differences 33 citations DOI OpenAlex
Stably Expressed Genes Involved in Basic Cellular Functions (2017)

PLoS ONE 4 citations DOI OpenAlex
Sex-related differential susceptibility to doxorubicin-induced cardiotoxicity in B6C3F1 mice (2016)

Toxicology and Applied Pharmacology 40 citations DOI OpenAlex