Jiřı́ Novotný Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Researcher

University of Arkansas
Last publication 2025 Last refreshed 2026-03-21

faculty

33 h-index 304 pubs 6,504 cited

Research Areas

Links

ORCID

OverviewAI-generated summary

Jiřı́ Novotný's research focuses on understanding molecular and cellular mechanisms underlying neurological and physiological processes. His work investigates signal transduction pathways, including those mediated by TRH receptors, and examines the role of specific molecules like cholesterol in neurodegenerative conditions such as Alzheimer's disease. Novotný has published on the impact of cholesterol on amyloid precursor protein processing and toxicity.

Further research interests include the neuroinflammatory response and the effects of opioid receptor activation on microglial polarization. He has also explored the biochemical and physiological aspects of opioid withdrawal, including proteomic changes in the rat brain associated with cytoskeleton and synaptic plasticity proteins. Additionally, his work has touched upon mitochondrial dysfunction in astrocytes, investigating potential therapeutic interventions such as FTO inhibitors.

Novotný's scholarship metrics include an h-index of 33, with over 304 publications and 6,500 citations. He is recognized as a highly cited researcher. Key collaborators at the University of Arkansas at Fayetteville include Erin L. Sauer, Ashley Morris, Sarah E. DuRant, and Weston Perrine.

Metrics

  • h-index: 33
  • Publications: 304
  • Citations: 6,504

Selected Publications

  • A high-lipid diet leads to greater pathology and lower tolerance during infection (2025)
    6 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

148 Collaborators 30 Institutions 7 Countries

Top Collaborators

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