Biography and Research Information
OverviewAI-generated summary
Perry C. Caviness's research focuses on the intersection of epigenetics, diet, and bone health, utilizing mouse models and human data. His work investigates how factors such as high-fat diets and specific dietary compounds, like phenolic acids and soy isoflavones, influence epigenetic modifications, including H3K27me3 and H3K27ac marks in bone tissue. These modifications are studied for their role in regulating osteoblastogenesis and preventing bone loss, particularly in the context of sex-steroid deficiency and high-fat diet-induced adipogenesis. Caviness also explores the impact of genetic factors, such as Ezh2 and GPR109A gene deletions in myeloid cells, on bone resorption and development. His research extends to understanding the connection between the gut microbiota and bone development, as well as investigating the ameliorative effects of certain compounds on bone resorption in conditions like multiple myeloma. Caviness has a h-index of 3 with 9 publications and 33 citations. He collaborates with researchers from the University of Arkansas at Fayetteville and the University of Arkansas for Medical Sciences.
Metrics
- h-index: 3
- Publications: 9
- Citations: 34
Selected Publications
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Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications (2025)
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Sex dependent effects of GPR109A gene deletion in myeloid cells on bone development in mice (2025)
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Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption (2025)
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Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice (2024)
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Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model (2023)
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Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice (2022)
Collaboration Network
Top Collaborators
Jin‐Ran Chen
Arkansas Children's Nutrition Center
9 shared publications
In database
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
- Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications
Showing 5 of 9 shared publications
Michael L. Blackburn
Arkansas Children's Nutrition Center
8 shared publications
In database
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
- Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications
Showing 5 of 8 shared publications
Oxana P. Lazarenko
Arkansas Children's Nutrition Center
8 shared publications
In database
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
- Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications
Showing 5 of 8 shared publications
Beau Belcher
Arkansas Children's Nutrition Center (US)
3 shared publications
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
Fenghuang Zhan
Winthrop Rockefeller Foundation (US)
3 shared publications
- Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
Jennifer F. Chen
Arkansas Children's Nutrition Center
3 shared publications
In database
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
- Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications
Haijun Zhao
Shandong University of Traditional Chinese Medicine (CN)
2 shared publications
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
Umesh D. Wankhade
2 shared publications
In database
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
Kartik Shankar
2 shared publications
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
Dongzheng Gai
Winthrop Rockefeller Foundation
2 shared publications
In database
- Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
Christopher E. Randolph
Arkansas Children's Hospital
2 shared publications
In database
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
Jovanny Zabaleta
Arkansas Children's Hospital (US)
1 shared publication
- Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
Zijun Zhang
Arkansas Children's Hospital
1 shared publication
In database
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
Yan Cheng
Winthrop Rockefeller Foundation (US)
1 shared publication
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
Fumou Sun
Winthrop Rockefeller Foundation
1 shared publication
In database
- Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption
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