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Presence Current · Arkansas
Last published 2025
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Perry C. Caviness

Researcher

Also affiliated: Arkansas Children's Hospital (2024); Arkansas Children's Nutrition Center (2022–2025)

Unknown Researcher

3 h-index 9 pubs 41 cited

  • Animals
  • Mice
  • Epigenesis, Genetic
  • Diet, High-Fat
  • Bone Resorption
  • Female
  • Male
  • Bone Development
  • Humans
  • Histones
  • Rats
  • Enhancer of Zeste Homolog 2 Protein
  • Osteoporosis
  • Mice, Knockout
  • Bone Diseases, Metabolic

Biography and Research Information

OverviewAI-generated summary

Perry C. Caviness's research focuses on the intersection of epigenetics, diet, and bone health, utilizing mouse models and human data. His work investigates how factors such as high-fat diets and specific dietary compounds, like phenolic acids and soy isoflavones, influence epigenetic modifications, including H3K27me3 and H3K27ac marks in bone tissue. These modifications are studied for their role in regulating osteoblastogenesis and preventing bone loss, particularly in the context of sex-steroid deficiency and high-fat diet-induced adipogenesis. Caviness also explores the impact of genetic factors, such as Ezh2 and GPR109A gene deletions in myeloid cells, on bone resorption and development. His research extends to understanding the connection between the gut microbiota and bone development, as well as investigating the ameliorative effects of certain compounds on bone resorption in conditions like multiple myeloma. Caviness has a h-index of 3 with 9 publications and 33 citations. He collaborates with researchers from the University of Arkansas at Fayetteville and the University of Arkansas for Medical Sciences.

Metrics

  • h-index: 3
  • Publications: 9
  • Citations: 41

Selected Publications

  • Soy Isoflavones Prevent Bone Quality Loss Induced by High‐Fat Diet in Rats Through Epigenetic Modifications (2025)
    The FASEB Journal 2 citations DOI OpenAlex
  • Sex dependent effects of GPR109A gene deletion in myeloid cells on bone development in mice (2025)
    Scientific Reports DOI OpenAlex
  • Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption (2025)
    Cancers 1 citation DOI OpenAlex
  • Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice (2024)
    The Journal of Nutritional Biochemistry 10 citations DOI OpenAlex
  • Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model (2023)
    The FASEB Journal 12 citations DOI OpenAlex
  • Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice (2022)
    Epigenetics 14 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

18 Collaborators 7 Institutions 1 Country

Top Collaborators

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