Sharda P. Singh

High Impact

Associate professor

University of Arkansas for Medical Sciences

faculty

25 h-index 110 pubs 2,579 cited

Research Areas

Neurological disorders and treatments Mitochondrial Function and Pathology Phytochemicals and Antioxidant Activities Diet and metabolism studies Cancer-related molecular mechanisms research Alzheimer's disease research and treatments Health and Medical Research Impacts

Links

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OverviewAI-generated summary

Sharda P. Singh's research investigates the molecular mechanisms underlying aging and age-related diseases, with a particular focus on oxidative stress, mitochondrial dysfunction, and neurodegeneration. Her work has explored the role of specific proteins, such as RALBP1 (RLIP76), in conditions like Alzheimer's disease, examining their involvement in oxidative stress and mitochondrial pathology using autopsy brains from patients.

Singh's publications also address the protective effects of dietary compounds. She has studied the impact of sulforaphane on skin aging and metabolic health through the Keap1-Nrf2 pathway, and the anticancer activity of omega-6 fatty acids in breast cancer cells. Additionally, her research has examined interventions for age-related conditions, including the prevention of skeletal muscle sarcopenia through iron chelation in mouse models of aging.

With an h-index of 25 and over 2,500 citations from 110 publications, Singh is recognized as a highly cited researcher. She has a history of collaboration with colleagues at the University of Arkansas for Medical Sciences, including Chhanda Bose, Philip Palade, Elisabet Børsheim, and Ashley Nemec-Bakk, with whom she has co-authored numerous publications.

Metrics

  • h-index: 25
  • Publications: 110
  • Citations: 2,579

Selected Publications

  • Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging (2025) DOI
  • Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway (2021) DOI

Collaborators

Researchers in the database who share publications

Chhanda Bose University of Arkansas for Medical Sciences 19 shared publications Philip Palade University of Arkansas for Medical Sciences 6 shared publications Elisabet Børsheim University of Arkansas for Medical Sciences 2 shared publications Ashley Nemec-Bakk University of Arkansas for Medical Sciences 1 shared publication Igor Koturbash University of Arkansas for Medical Sciences 1 shared publication Laura Ewing University of Arkansas for Medical Sciences 1 shared publication Isabelle Racine Miousse University of Arkansas for Medical Sciences 1 shared publication John Lowery University of Arkansas for Medical Sciences 1 shared publication

Similar Researchers

Based on overlapping research topics

Roman Brudnik University of Arkansas for Medical Sciences
Mitochondrial Function and Pathology Phytochemicals and Antioxidant Activities Diet and metabolism studies
Good match 4 shared topics
Francielle Morena Da Silva University of Arkansas at Fayetteville
Mitochondrial Function and Pathology Diet and metabolism studies Cancer-related molecular mechanisms research
Good match 4 shared topics
Anna Bragg University of Arkansas for Medical Sciences
Phytochemicals and Antioxidant Activities Diet and metabolism studies Cancer-related molecular mechanisms research
Good match 4 shared topics
Chhanda Bose University of Arkansas for Medical Sciences
Neurological disorders and treatments Mitochondrial Function and Pathology Diet and metabolism studies
Good match 5 shared topics
J Panos National Center for Toxicological Research
Neurological disorders and treatments Diet and metabolism studies Alzheimer's disease research and treatments
Good match 4 shared topics
Harrison Brown University of Arkansas for Medical Sciences
Mitochondrial Function and Pathology Diet and metabolism studies Cancer-related molecular mechanisms research
Good match 4 shared topics