S
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Sonu Pahal's research investigates neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, with a focus on identifying potential therapeutic targets and drug candidates. This work involves computational biology and molecular docking simulations to evaluate natural compounds, such as those found in *Withania somnifera*, for their inhibitory effects against disease-related targets. Pahal also explores the role of mitochondria in aging and age-associated diseases and examines the potential of compounds like ezetimibe to mitigate Alzheimer's risk by targeting specific molecular interactions. The research network includes collaborators from the University of Arkansas for Medical Sciences, such as Meenakshisundaram Balasubramaniam and Srinivas Ayyadevara. Pahal has authored 15 publications, with an h-index of 6 and 97 citations.
Metrics
- h-index: 6
- Publications: 15
- Citations: 106
Selected Publications
-
Brain peptides in Alzheimer’s disease - pathophysiology and therapeutic advances (2026)
-
The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease (2026)
-
Role of Monoclonal Antibodies in Alzheimer’s Disease: Successes, Failures, and Future Directions (2025)
-
Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology (2025)
-
Mitochondria in aging and age-associated diseases (2025)
-
From data to discovery: Neuroinformatics in understanding Alzheimer's disease (2024)
-
Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction (2024)
Collaboration Network
Top Collaborators
Amit Chaudhary
University of Alabama at Birmingham (US)
6 shared publications
- Network pharmacological evaluation of <i>Withania somnifera</i> bioactive phytochemicals for identifying novel potential inhibitors against neurodegenerative disorder
- Screening of Natural Compounds Against SOD1 as a Therapeutic Targetfor Amyotrophic Lateral Sclerosis
- From data to discovery: Neuroinformatics in understanding Alzheimer's disease
- Role of Monoclonal Antibodies in Alzheimer’s Disease: Successes, Failures, and Future Directions
- Network pharmacological evaluation of <i>Withania somnifera</i> bioactive phytochemicals for identifying novel potential inhibitors against neurodegenerative disorder
Showing 5 of 6 shared publications
Sangeeta Singh
6 shared publications
- Network pharmacological evaluation of <i>Withania somnifera</i> bioactive phytochemicals for identifying novel potential inhibitors against neurodegenerative disorder
- Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer’s and Parkinson’s diseases as druggable targets through <i>Withania somnifera</i> bioactives: an <i>in silico</i> study
- Regulation of neuronal repair and regeneration through inhibition of oligodendrocyte myelin glycoprotein (OMgp)
- Screening of Natural Compounds Against SOD1 as a Therapeutic Targetfor Amyotrophic Lateral Sclerosis
- Network pharmacological evaluation of strigolactones efficacy as potential inhibitors against therapeutic targets of hepatocellular carcinoma
Showing 5 of 6 shared publications
Meenakshisundaram Balasubramaniam
University of Arkansas for Medical Sciences
6 shared publications
In database
- Mitochondria in aging and age-associated diseases
- Alzheimer’s-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Tools of Artificial Intelligence in the Improvement of Synaptic Impairment in Different Neurodegenerative Diseases
- Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology
Showing 5 of 6 shared publications
Ayushi Gupta
5 shared publications
- Network pharmacological evaluation of <i>Withania somnifera</i> bioactive phytochemicals for identifying novel potential inhibitors against neurodegenerative disorder
- Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer’s and Parkinson’s diseases as druggable targets through <i>Withania somnifera</i> bioactives: an <i>in silico</i> study
- Regulation of neuronal repair and regeneration through inhibition of oligodendrocyte myelin glycoprotein (OMgp)
- Network pharmacological evaluation of strigolactones efficacy as potential inhibitors against therapeutic targets of hepatocellular carcinoma
- Network pharmacological evaluation of <i>Withania somnifera</i> bioactive phytochemicals for identifying novel potential inhibitors against neurodegenerative disorder
Princy Choudhary
5 shared publications
- Network pharmacological evaluation of <i>Withania somnifera</i> bioactive phytochemicals for identifying novel potential inhibitors against neurodegenerative disorder
- Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer’s and Parkinson’s diseases as druggable targets through <i>Withania somnifera</i> bioactives: an <i>in silico</i> study
- Regulation of neuronal repair and regeneration through inhibition of oligodendrocyte myelin glycoprotein (OMgp)
- Network pharmacological evaluation of strigolactones efficacy as potential inhibitors against therapeutic targets of hepatocellular carcinoma
- Network pharmacological evaluation of <i>Withania somnifera</i> bioactive phytochemicals for identifying novel potential inhibitors against neurodegenerative disorder
Srinivas Ayyadevara
University of Arkansas at Little Rock
5 shared publications
In database
- Mitochondria in aging and age-associated diseases
- Alzheimer’s-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology
- The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease
Nirjal Mainali
University of Arkansas at Little Rock
4 shared publications
In database
- Mitochondria in aging and age-associated diseases
- Alzheimer’s-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology
Robert J. Shmookler Reis
Institute on Aging
4 shared publications
In database
- Mitochondria in aging and age-associated diseases
- Alzheimer’s-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology
Akshatha Ganne
University of Arkansas for Medical Sciences
3 shared publications
In database
- Alzheimer’s-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease
Vishvender Pahal
National Institute of Pharmaceutical Education and Research (IN)
3 shared publications
- Tools of Artificial Intelligence in the Improvement of Synaptic Impairment in Different Neurodegenerative Diseases
- From data to discovery: Neuroinformatics in understanding Alzheimer's disease
- Brain peptides in Alzheimer’s disease - pathophysiology and therapeutic advances
Richa Shukla
Indian Institute of Information Technology Allahabad (IN)
2 shared publications
- Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer’s and Parkinson’s diseases as druggable targets through <i>Withania somnifera</i> bioactives: an <i>in silico</i> study
- Regulation of neuronal repair and regeneration through inhibition of oligodendrocyte myelin glycoprotein (OMgp)
Arushi Gupta
Amity University (IN)
2 shared publications
- Role of Monoclonal Antibodies in Alzheimer’s Disease: Successes, Failures, and Future Directions
- Brain peptides in Alzheimer’s disease - pathophysiology and therapeutic advances
Shivani Gupta
Indian Institute of Information Technology Allahabad (IN)
1 shared publication
- Regulation of neuronal repair and regeneration through inhibition of oligodendrocyte myelin glycoprotein (OMgp)
Krishna Misra
Indian Institute of Information Technology Allahabad (IN)
1 shared publication
- Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer’s and Parkinson’s diseases as druggable targets through <i>Withania somnifera</i> bioactives: an <i>in silico</i> study
Ayush Amod
Indian Institute of Information Technology Allahabad (IN)
1 shared publication
- Network pharmacological evaluation of strigolactones efficacy as potential inhibitors against therapeutic targets of hepatocellular carcinoma
Similar Researchers
Based on overlapping research topics
Nirjal Mainali
University of Arkansas for Medical Sciences
Neurological disorders and treatments
Neuroscience and Neuropharmacology Research
Dementia and Cognitive Impairment Research
Khaled Dostzada
University of Arkansas for Medical Sciences
Neurological disorders and treatments
Neuroscience and Neuropharmacology Research
Dementia and Cognitive Impairment Research
Sue Griffin
University of Arkansas for Medical Sciences
Neurological disorders and treatments
Dementia and Cognitive Impairment Research
Mitochondrial Function and Pathology
Syed Z. Imam
National Center for Toxicological Research
Neurological disorders and treatments
Neuroscience and Neuropharmacology Research
Mitochondrial Function and Pathology
Sienna Colonese
University of Arkansas for Medical Sciences
Neurological disorders and treatments
Neuroscience and Neuropharmacology Research
Dementia and Cognitive Impairment Research
Antiño R. Allen
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Dementia and Cognitive Impairment Research
Mitochondrial Function and Pathology