Sonu Pahal
Researcher
Also affiliated: Indian Institute of Information Technology Allahabad (2021–2022); Institute on Aging (2024–2025); Indian Institute of Technology Indore (2021)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Sonu Pahal's research investigates neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, with a focus on identifying potential therapeutic targets and drug candidates. This work involves computational biology and molecular docking simulations to evaluate natural compounds, such as those found in *Withania somnifera*, for their inhibitory effects against disease-related targets. Pahal also explores the role of mitochondria in aging and age-associated diseases and examines the potential of compounds like ezetimibe to mitigate Alzheimer's risk by targeting specific molecular interactions. The research network includes collaborators from the University of Arkansas for Medical Sciences, such as Meenakshisundaram Balasubramaniam and Srinivas Ayyadevara. Pahal has authored 15 publications, with an h-index of 6 and 97 citations.
Metrics
- h-index: 6
- Publications: 15
- Citations: 116
Selected Publications
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Brain peptides in Alzheimer’s disease - pathophysiology and therapeutic advances (2026)
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The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease (2026)
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Role of Monoclonal Antibodies in Alzheimer’s Disease: Successes, Failures, and Future Directions (2025)
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Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology (2025)
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Mitochondria in aging and age-associated diseases (2025)
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From data to discovery: Neuroinformatics in understanding Alzheimer's disease (2024)
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Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction (2024)
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Alzheimer’s-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets (2023)
Collaboration Network
Top Collaborators
- Mitochondria in aging and age-associated diseases
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology
- The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease
- Mitochondria in aging and age-associated diseases
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology
- The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease
- Mitochondria in aging and age-associated diseases
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology
- Mitochondria in aging and age-associated diseases
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology
- From data to discovery: Neuroinformatics in understanding Alzheimer's disease
- Role of Monoclonal Antibodies in Alzheimer’s Disease: Successes, Failures, and Future Directions
- Brain peptides in Alzheimer’s disease - pathophysiology and therapeutic advances
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease
- From data to discovery: Neuroinformatics in understanding Alzheimer's disease
- Brain peptides in Alzheimer’s disease - pathophysiology and therapeutic advances
- Role of Monoclonal Antibodies in Alzheimer’s Disease: Successes, Failures, and Future Directions
- Brain peptides in Alzheimer’s disease - pathophysiology and therapeutic advances
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction
- Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology
- Role of Monoclonal Antibodies in Alzheimer’s Disease: Successes, Failures, and Future Directions
- The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease
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