Match tier
Likely match
Presence
Current · Arkansas
Last published
2022
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
S
Syed Z. Imam
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
High Impact
Role not yet determined Is this you? Add your title
Also affiliated: National Institutes of Health (2005–2007); United States Food and Drug Administration (1999–2022); The University of Texas at San Antonio Health Science Center (2005–2013); Jamia Hamdard (2002); Aarhus University (2007); Audie L. Murphy Memorial VA Hospital (2010); National Institute on Aging (2005–2007); South Texas Veterans Health Care System (2005–2007)
35 h-index
69 pubs
3,351 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Syed Z. Imam's research focuses on the molecular mechanisms of neurodegenerative diseases, particularly Parkinson's disease, and the neurotoxic effects of various substances. He has investigated the role of protein phosphorylation in regulating Parkin function, a key factor in Parkinson's disease pathogenesis. His work has also explored neuroprotective strategies against Parkinson's disease, examining the impact of antioxidants and peroxynitrite decomposition catalysts on methamphetamine-induced dopaminergic neurotoxicity.
Imam's research extends to DNA repair mechanisms, with studies on the age-dependent alterations in DNA-repair capacity in different brain regions of mice. He has also examined the role of nitric oxide in rotenone-induced nigro-striatal injury and the influence of specific proteins on DNA repair pathways. His collaborations include extensive work with researchers at the National Center for Toxicological Research, including Syed F. Ali, Héctor Rosas-Hernández, Susan M. Lantz, and Merle G. Paule.
With an h-index of 35, 69 publications, and over 3,351 citations, Imam is recognized as a highly cited researcher. He leads a research group and has remained active in research with recent publications in 2022.
Metrics
- h-index: 35
- Publications: 69
- Citations: 3,351
Selected Publications
-
Autophagy and protein aggregation as a mechanism of dopaminergic degeneration in a primary human dopaminergic neuronal model (2022)
-
Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity (2021)
-
Dr. Daniel Acosta and In Vitro toxicology at the U.S. Food and Drug Administration's National Center for Toxicological Research (2019)
-
The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson’s Disease (2019)
-
Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro (2019)
-
A Method for Sampling Rat Cerebrospinal Fluid with Minimal Blood Contamination: A Critical Tool for Biomarker Studies (2019)
-
Cytotoxicity profile of pristine graphene on brain microvascular endothelial cells (2019)
-
Drug discovery and development: Biomarkers of neurotoxicity and neurodegeneration (2018)
-
Characterization of uniaxial high-speed stretch as an in vitro model of mild traumatic brain injury on the blood-brain barrier (2018)
-
Ontogeny of Monoamine Neurotransmitters (2018)
-
Ontogeny of Second Messenger Systems (2018)
-
Blood–Brain Barrier: Physiological and Functional Considerations (2018)
-
Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study (2017)
-
Characterization of Biaxial Stretch as an In Vitro Model of Traumatic Brain Injury to the Blood-Brain Barrier (2017)
-
Monoaminergic toxicity induced by cathinone phthalimide: An in vitro study (2017)
Collaboration Network
Top Collaborators
Syed F. Ali
National Center for Toxicological Research
39 shared publications
In database
- Methamphetamine‐Induced Dopaminergic Neurotoxicity: Role of Peroxynitrite and Neuroprotective Role of Antioxidants and Peroxynitrite Decomposition Catalysts
- Selenium, an antioxidant, attenuates methamphetamine-induced dopaminergic toxicity and peroxynitrite generation
- Role of nitric oxide in rotenone‐induced nigro‐striatal injury
- Peroxynitrite plays a role in methamphetamine‐induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper–zinc superoxide dismutase
- Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage
Showing 5 of 39 shared publications
William Slikker
18 shared publications
In database
- Methamphetamine‐Induced Dopaminergic Neurotoxicity: Role of Peroxynitrite and Neuroprotective Role of Antioxidants and Peroxynitrite Decomposition Catalysts
- Peroxynitrite plays a role in methamphetamine‐induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper–zinc superoxide dismutase
- Selenium, an antioxidant, protects against methamphetamine-induced dopaminergic neurotoxicity
- Neuroprotective Efficacy of a New Brain-Penetrating C-Abl Inhibitor in a Murine Parkinson’s Disease Model
- Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: protective effects of peroxynitrite decomposition catalyst
Showing 5 of 18 shared publications
Merle G. Paule
National Center for Toxicological Research
13 shared publications
In database
- Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage
- Neuroprotective Efficacy of a New Brain-Penetrating C-Abl Inhibitor in a Murine Parkinson’s Disease Model
- Protein Kinases and Parkinson’s Disease
- Chronic exposure to rotenone, a dopaminergic toxin, results in peripheral neuropathy associated with dopaminergic damage
- Characterization of Biaxial Stretch as an In Vitro Model of Traumatic Brain Injury to the Blood-Brain Barrier
Showing 5 of 13 shared publications
Elvis Cuevas
National Center for Toxicological Research (US)
13 shared publications
- Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage
- Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro
- Protein Kinases and Parkinson’s Disease
- Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study
- Characterization of Biaxial Stretch as an In Vitro Model of Traumatic Brain Injury to the Blood-Brain Barrier
Showing 5 of 13 shared publications
Héctor Rosas-Hernández
National Center for Toxicological Research
11 shared publications
In database
- Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage
- Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro
- Protein Kinases and Parkinson’s Disease
- Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study
- Characterization of Biaxial Stretch as an In Vitro Model of Traumatic Brain Injury to the Blood-Brain Barrier
Showing 5 of 11 shared publications
Sumit Sarkar
National Center for Toxicological Research
10 shared publications
In database
- Neuroprotective and Therapeutic Strategies against Parkinson’s Disease: Recent Perspectives
- Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage
- Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro
- Protein Kinases and Parkinson’s Disease
- Chronic exposure to rotenone, a dopaminergic toxin, results in peripheral neuropathy associated with dopaminergic damage
Showing 5 of 10 shared publications
Susan M. Lantz
National Center for Toxicological Research
9 shared publications
In database
- Protein Kinases and Parkinson’s Disease
- Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study
- Characterization of Biaxial Stretch as an In Vitro Model of Traumatic Brain Injury to the Blood-Brain Barrier
- Characterization of uniaxial high-speed stretch as an in vitro model of mild traumatic brain injury on the blood-brain barrier
- Cytotoxicity profile of pristine graphene on brain microvascular endothelial cells
Showing 5 of 9 shared publications
Glenn D. Newport
National Center for Toxicological Research
8 shared publications
In database
- Methamphetamine‐Induced Dopaminergic Neurotoxicity: Role of Peroxynitrite and Neuroprotective Role of Antioxidants and Peroxynitrite Decomposition Catalysts
- Peroxynitrite plays a role in methamphetamine‐induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper–zinc superoxide dismutase
- Selenium, an antioxidant, protects against methamphetamine-induced dopaminergic neurotoxicity
- Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: protective effects of peroxynitrite decomposition catalyst
- Ibogaine blocked methamphetamine-induced hyperthermia and induction of heat shock protein in mice
Showing 5 of 8 shared publications
Yossef Itzhak
University of Miami (US)
7 shared publications
- Methamphetamine‐Induced Dopaminergic Neurotoxicity: Role of Peroxynitrite and Neuroprotective Role of Antioxidants and Peroxynitrite Decomposition Catalysts
- Peroxynitrite plays a role in methamphetamine‐induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper–zinc superoxide dismutase
- Prevention of Dopaminergic Neurotoxicity by Targeting Nitric Oxide and Peroxynitrite: Implications for the Prevention of Methamphetamine‐induced Neurotoxic Damage
- Methamphetamine-induced alteration in striatal p53 and bcl-2 expressions in mice
- Role of Peroxynitrite in Methamphetamine‐Induced Dopaminergic Neurodegeneration and Neuroprotection by Antioxidants and Selective NOS Inhibitors
Showing 5 of 7 shared publications
Fakhrul Islam
Jamia Hamdard (IN)
6 shared publications
- Peroxynitrite plays a role in methamphetamine‐induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper–zinc superoxide dismutase
- Selenium, an antioxidant, protects against methamphetamine-induced dopaminergic neurotoxicity
- Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: protective effects of peroxynitrite decomposition catalyst
- Prevention of Dopaminergic Neurotoxicity by Targeting Nitric Oxide and Peroxynitrite: Implications for the Prevention of Methamphetamine‐induced Neurotoxic Damage
- Methamphetamine-induced alteration in striatal p53 and bcl-2 expressions in mice
Showing 5 of 6 shared publications
ZBIGNIEW K. BINIENDA
National Center for Toxicological Research (US)
6 shared publications
- Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage
- Neuroprotective Efficacy of a New Brain-Penetrating C-Abl Inhibitor in a Murine Parkinson’s Disease Model
- The Protective Role of l‐Carnitine against Neurotoxicity Evoked by Drug of Abuse, Methamphetamine, Could Be Related to Mitochondrial Dysfunction
- Possible Mechanism for the Neuroprotective Effects of l‐Carnitine on Methamphetamine‐Evoked Neurotoxicity
- Molecular Aspects of Dopaminergic Neurodegeneration: Gene-Environment Interaction in Parkin Dysfunction
Showing 5 of 6 shared publications
B. Gough
National Center for Toxicological Research (US)
4 shared publications
- Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage
- Comparative Effects of Substituted Amphetamines (PMA, MDMA, and METH) on Monoamines in Rat Caudate
- Chronic exposure to rotenone, a dopaminergic toxin, results in peripheral neuropathy associated with dopaminergic damage
- Acute changes in dopamine release and turnover in rat caudate nucleus following a single dose of methamphetamine
James B. Raymick
National Center for Toxicological Research
4 shared publications
In database
- Neuroprotective and Therapeutic Strategies against Parkinson’s Disease: Recent Perspectives
- Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study
- A Method for Sampling Rat Cerebrospinal Fluid with Minimal Blood Contamination: A Critical Tool for Biomarker Studies
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
Bonnie L. Robinson
National Center for Toxicological Research
4 shared publications
In database
- Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage
- Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study
- Monoaminergic toxicity induced by cathinone phthalimide: An in vitro study
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
Serguei M. Liachenko
National Center for Toxicological Research
4 shared publications
In database
- Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage
- Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study
- A Method for Sampling Rat Cerebrospinal Fluid with Minimal Blood Contamination: A Critical Tool for Biomarker Studies
- Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
Similar Researchers
Based on overlapping research topics
Urooj Fatima
University of Arkansas for Medical Sciences
Disease Models, Animal
Molecular Biology Techniques and Applications
Neuroscience and Neuropharmacology Research
Yusuke Kishimoto
University of Arkansas for Medical Sciences
Disease Models, Animal
Molecular Biology Techniques and Applications
Neuroscience and Neuropharmacology Research
David W. Donley
Harding University Main Campus
Disease Models, Animal
Molecular Biology Techniques and Applications
Neuroscience and Neuropharmacology Research
Melanie C MacNicol
University of Arkansas for Medical Sciences
Disease Models, Animal
Molecular Biology Techniques and Applications
Neuroscience and Neuropharmacology Research
Linda L. Hardy
University of Arkansas for Medical Sciences
Disease Models, Animal
Molecular Biology Techniques and Applications
Neuroscience and Neuropharmacology Research
Jyotshna Kanungo
National Center for Toxicological Research
Disease Models, Animal
Molecular Biology Techniques and Applications
Neuroscience and Neuropharmacology Research