V
Vivek Govind Kumar Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
faculty
7 h-index
31 pubs
177 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Vivek Govind Kumar's research employs molecular dynamics simulations to investigate protein structure and dynamics. His work has focused on understanding the conformational changes of viral proteins, such as the SARS-CoV-2 spike protein and influenza hemagglutinin. He also studies the stabilization mechanisms of human proteins, including fibroblast growth factor 1, by examining their interactions with molecules like heparin. Kumar's research addresses fundamental questions about protein folding, binding affinities, and the forces that govern protein stability and reversibility. His publication record includes studies on intrinsically disordered protein regions and the structural insights gained from combining experimental and computational approaches. Kumar collaborates with researchers at the University of Arkansas at Fayetteville and the University of Arkansas at Little Rock, with shared publications numbering as high as 14 with Mahmoud Moradi.
Metrics
- h-index: 7
- Publications: 31
- Citations: 177
Selected Publications
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Molecular Dynamics Investigation of the Influenza Hemagglutinin Conformational Changes in Acidic pH (2024)
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Molecular dynamics investigation of the influenza hemagglutinin conformational changes in acidic pH (2024)
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A purely physics-based computational binding affinity estimation from restrained umbrella sampling simulations (2024)
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cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach (2023)
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Structural effects of ALS-associated mutations on profilin (2023)
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Binding affinity estimation from restrained umbrella sampling simulations (2022)
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Binding Affinity Estimation from Restrained Umbrella Sampling Simulations (2022)
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Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1 (2022)
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Molecular dynamics investigation of the ph-dependent influenza hemagglutinin conformational change (2022)
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Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein (2022)
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cpSRP43 is both highly flexible and stable: Structural insights using a combined experimental and computational approach (2022)
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Binding Affinity Estimation From Restrained Umbrella Sampling Simulations (2021)
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Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding (2021)
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Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase (2021)
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Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor (2021)
Collaboration Network
Top Collaborators
Mahmoud Moradi
University of Arkansas at Fayetteville
20 shared publications
In database
- Binding affinity estimation from restrained umbrella sampling simulations
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
- Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
Showing 5 of 20 shared publications
Thallapuranam Krishnaswamy Suresh Kumar
University of Arkansas at Fayetteville
8 shared publications
In database
- Binding affinity estimation from restrained umbrella sampling simulations
- Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
- Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Binding Affinity Estimation from Restrained Umbrella Sampling Simulations
Showing 5 of 8 shared publications
Adithya Polasa
University of Arkansas at Fayetteville
7 shared publications
In database
- Binding affinity estimation from restrained umbrella sampling simulations
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Comparing the Dynamic Differences between X-ray and Cryo-EM Structures of Cannabinoid Receptor 1 using Molecular Dynamics Simulations
- cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach
- A purely physics-based computational binding affinity estimation from restrained umbrella sampling simulations
Showing 5 of 7 shared publications
Shilpi Agrawal
University of Arkansas at Fayetteville
5 shared publications
In database
- Binding affinity estimation from restrained umbrella sampling simulations
- Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
- Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding
- Binding Affinity Estimation from Restrained Umbrella Sampling Simulations
- Binding Affinity Estimation From Restrained Umbrella Sampling Simulations
Ugochi H. Isu
University of Arkansas at Fayetteville
4 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Comparing the Dynamic Differences between X-ray and Cryo-EM Structures of Cannabinoid Receptor 1 using Molecular Dynamics Simulations
- Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2
- Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein
James Losey
University of Arkansas at Fayetteville
4 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2
- Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein
Mercede Furr
University of Arkansas at Fayetteville
4 shared publications
In database
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach
- Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein
- cpSRP43 is both highly flexible and stable: Structural insights using a combined experimental and computational approach
Colin D. Heyes
University of Arkansas at Fayetteville
4 shared publications
In database
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach
- Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein
- cpSRP43 is both highly flexible and stable: Structural insights using a combined experimental and computational approach
Dylan S. Ogden
University of Arkansas at Fayetteville
3 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2
- An Investigation of the Conformational Dynamics of ABC Exporter PCAT1 using Microsecond-Level MD Simulations
Dustin Baucom
University of Arkansas at Fayetteville
2 shared publications
In database
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein
Mitchell Benton
University of Arkansas at Fayetteville
2 shared publications
In database
- cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach
- cpSRP43 is both highly flexible and stable: Structural insights using a combined experimental and computational approach
Mortaza Derakhshani-Molayousefi
University of Arkansas at Fayetteville
2 shared publications
In database
- Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein
- Structural effects of ALS-associated mutations on profilin
Shadi A. Badiee
University of Arkansas at Fayetteville
2 shared publications
In database
- Molecular Dynamics Investigation of the Influenza Hemagglutinin Conformational Changes in Acidic pH
- Molecular dynamics investigation of the influenza hemagglutinin conformational changes in acidic pH
Shadi Asadian Ghahfarokhi
University of Arkansas at Fayetteville
1 shared publication
In database
- Molecular Dynamics Investigation of the Influenza Hemagglutinin Conformational Changes
Suresh Kumar
University of Arkansas at Fayetteville (US)
1 shared publication
- Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein
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