William H. Tolleson Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Research Chemist

National Center for Toxicological Research

faculty

32 h-index 66 pubs 2,517 cited

Research Areas

Pharmacological Effects and Toxicity Studies Protein Structure and Dynamics Molecular Biology Techniques and Applications Carcinogens and Genotoxicity Assessment Liver Disease Diagnosis and Treatment

Links

ORCID Lab Website

Is this your profile? Verify and claim your profile

OverviewAI-generated summary

William H. Tolleson's research centers on the toxicological assessment of drugs and chemicals, particularly focusing on liver toxicity. He investigates cellular models, such as cytochrome P450 (CYP)-overexpressing HepG2 cells, to understand how these substances induce adverse effects. His work also extends to the biophysical characterization of proteins, including microcalorimetric studies of protein unfolding. Tolleson has published 66 papers, accumulating over 2,500 citations and an h-index of 32, reflecting his significant contributions to the field. He actively collaborates with researchers at the National Center for Toxicological Research and the University of Arkansas for Medical Sciences, contributing to a network of scientific inquiry in toxicology and molecular biology.

Metrics

  • h-index: 32
  • Publications: 66
  • Citations: 2,517

Selected Publications

  • Microcalorimetric Investigations of Reversible Staphylococcal Enterotoxin Unfolding (2022) DOI
  • Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity (2021) DOI

Collaborators

Researchers in the database who share publications

Odbert A. Triplett National Center for Toxicological Research 1 shared publication Mark E. Hart University of Arkansas for Medical Sciences 1 shared publication Nan Mei National Center for Toxicological Research 1 shared publication Qiangen Wu National Center for Toxicological Research 1 shared publication

Similar Researchers

Based on overlapping research topics

Stephan Melnyk University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Protein Structure and Dynamics Molecular Biology Techniques and Applications
Strong match 3 shared topics
W. SLIKKKER National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Molecular Biology Techniques and Applications Carcinogens and Genotoxicity Assessment
Good match 3 shared topics
Clare L. Ritter National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Molecular Biology Techniques and Applications Carcinogens and Genotoxicity Assessment
Good match 3 shared topics
Sharon D. Shelton National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Molecular Biology Techniques and Applications Carcinogens and Genotoxicity Assessment
Good match 3 shared topics
Yuet-Kin Leung University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Molecular Biology Techniques and Applications Carcinogens and Genotoxicity Assessment
Good match 3 shared topics
Alan Herrera-Rueda University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Protein Structure and Dynamics Molecular Biology Techniques and Applications
Good match 3 shared topics