Biography and Research Information
OverviewAI-generated summary
Yunping Guo's research focuses on the interplay between the immune system and hypertension, particularly salt-sensitive forms. Guo has investigated the role of specific immune cells and pathways in the development and progression of hypertension. Recent work has explored how CD8+ T cells interact with kidney tubules, specifically distal convoluted tubules, and how this interaction, mediated by the IFNγ-PDL1 pathway, contributes to hypertension. Additionally, Guo's research has examined the contribution of immune memory to chronic hypertension recurrence and the involvement of innate immune components in hypertension-induced cardiac dysfunction. The work also delves into how P2X7 receptor activation in CD8+ T cells can promote salt-sensitive hypertension independently of antigen presentation. Guo's scholarship metrics include an h-index of 3 across 16 publications with 65 citations.
Metrics
- h-index: 3
- Publications: 17
- Citations: 68
Selected Publications
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Abstract P200: Immune memory contributes to chronic hypertension recurrence (2024)
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Abstract P335: An innate immune component in hypertension-induced cardiac dysfunction Christoph Mora, Katherine Deck, Yunmeng Liu, Lance Benson, Tonya Rafferty, & Shengyu Mu (2024)
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P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION (2024)
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O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION (2024)
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Kidney resident memory CD8 T cells mediate recurrence of salt-sensitive hypertension (2024)
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Macrophage to Myofibroblast Transition Promotes Hypertension-Induced Cardiac Diastolic Dysfunction (2024)
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Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development (2023)
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The link between immunity and hypertension in the kidney and heart (2023)
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S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION (2023)
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The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension (2022)
Collaboration Network
Top Collaborators
Lance Benson
University of Arkansas for Medical Sciences (US)
16 shared publications
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- The link between immunity and hypertension in the kidney and heart
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
Showing 5 of 16 shared publications
Shengyu Mu
University of Arkansas for Medical Sciences
16 shared publications
In database
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- The link between immunity and hypertension in the kidney and heart
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
Showing 5 of 16 shared publications
Katherine Deck
University of Arkansas for Medical Sciences
15 shared publications
In database
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- The link between immunity and hypertension in the kidney and heart
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
- Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development
Showing 5 of 15 shared publications
Christoph Mora
University of Arkansas for Medical Sciences
15 shared publications
In database
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- The link between immunity and hypertension in the kidney and heart
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
- Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development
Showing 5 of 15 shared publications
Yunmeng Liu
University of Arkansas for Medical Sciences (US)
13 shared publications
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- The link between immunity and hypertension in the kidney and heart
- The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
- Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development
Showing 5 of 13 shared publications
Yunzhao Xiong
University of Arkansas for Medical Sciences (US)
3 shared publications
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
Tonya Rafferty
University of Arkansas for Medical Sciences
3 shared publications
In database
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
Yunmeng Liu
University of Arkansas for Medical Sciences
3 shared publications
In database
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- Antigen-Independent Activation of CD8 T Cells Promotes Salt Sensitive Hypertension
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
Lin‐Xi Li
2 shared publications
In database
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
Lu Huang
2 shared publications
In database
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
J. Tucker Andrews
2 shared publications
In database
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
Zhiqiang Qin
University of Arkansas for Medical Sciences (US)
2 shared publications
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
Robert S. Hoover
Tulane University (US)
2 shared publications
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
Xiangting Wang
1 shared publication
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
Sung W. Rhee
1 shared publication
In database
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
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