Nathan C. Twaddle Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Senior Scientist / Toxicologist

National Center for Toxicological Research

faculty

34 h-index 61 pubs 4,064 cited

Research Areas

Pharmacological Effects and Toxicity Studies Neuroscience and Neuropharmacology Research Diet and metabolism studies Gut microbiota and health Carcinogens and Genotoxicity Assessment Metabolomics and Mass Spectrometry Studies Birth, Development, and Health

Links

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OverviewAI-generated summary

Nathan C. Twaddle's research investigates the toxicological effects of various substances, particularly inorganic arsenic, on biological systems. His work has explored how inorganic arsenic impacts neuronal development in zebrafish, specifically affecting dopaminergic and motor neurons through pathways like Sonic hedgehog. Twaddle has also examined the gene expression alterations induced by inorganic arsenic, linking them to apoptosis in zebrafish.

In addition to arsenic, Twaddle's research extends to the effects of dietary components, such as soy protein concentrates with varying isoflavone levels, on metabolic health. Studies have investigated these effects in rat models, focusing on serum isoflavone levels, inflammatory markers, and the reversal of obesity-induced liver steatosis. His work has also included the analysis of elemental impurities in cannabis following vaporization.

Twaddle collaborates with researchers from the National Center for Toxicological Research, including Jyotshnabala Kanungo, Frederick A. Beland, and Camila Silva, as well as Reza Hakkak from the University of Arkansas for Medical Sciences. He has a h-index of 34, with 61 publications and over 4,000 citations.

Metrics

  • h-index: 34
  • Publications: 61
  • Citations: 4,064

Selected Publications

  • Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development (2025) DOI
  • Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level (2024) DOI
  • Analysis of elemental impurities in cannabis following vaporization (2023) DOI
  • Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish (2023) DOI
  • Feeding Soy Protein Concentrates with Low and High Isoflavones Alters 9 and 18 Weeks Serum Isoflavones and Inflammatory Protein Levels in Lean and Obese Zucker Rats (2023) DOI
  • Effects of 8 Weeks Feeding Diet with Low and High Isoflavones Soy Protein Concentrate on Serum Isoflavones in Non-alcoholic Fatty Liver Disease (NAFLD) Rat Model (2022) DOI

Collaborators

Researchers in the database who share publications

Jyotshnabala Kanungo National Center for Toxicological Research 3 shared publications Frederick A. Beland National Center for Toxicological Research 3 shared publications Camila Silva National Center for Toxicological Research 3 shared publications Reza Hakkak University of Arkansas for Medical Sciences 3 shared publications Qiang Gu National Center for Toxicological Research 2 shared publications Bonnie Robinson National Center for Toxicological Research 2 shared publications Soheila Korourian University of Arkansas for Medical Sciences 2 shared publications Volodymyr Tryndyak National Center for Toxicological Research 1 shared publication

Similar Researchers

Based on overlapping research topics

Camila Silva National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Neuroscience and Neuropharmacology Research Diet and metabolism studies
Good match 5 shared topics
Héctor Rosas-Hernández National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Neuroscience and Neuropharmacology Research Carcinogens and Genotoxicity Assessment
Good match 5 shared topics
Sherry M. Lewis National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Neuroscience and Neuropharmacology Research Diet and metabolism studies
Good match 4 shared topics
Bonnie Robinson National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Neuroscience and Neuropharmacology Research Carcinogens and Genotoxicity Assessment
Good match 5 shared topics
W. Du University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Neuroscience and Neuropharmacology Research Diet and metabolism studies
Good match 3 shared topics
Renny Shang-Lun Lan University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Diet and metabolism studies Gut microbiota and health
Good match 5 shared topics