Biography and Research Information
OverviewAI-generated summary
James D. Sikes' research investigates the influence of diet and environmental factors on host-microbe interactions and metabolic health. His work has explored how maternal high-fat diets impact offspring gut microbiota and how changes in housing temperature affect energy expenditure and adipocyte function in mice. Sikes has also examined the role of specific microbial species, such as *Lachnoclostridium scindens*, in response to C-section birth. Additionally, his research extends to regenerative biology, with studies on wound responses in holobionts and the genetic control of regeneration in *Hofstenia miamia*. He has also evaluated the effects of plant-based infant formulas on gut microbiota and metabolic markers in piglets. Sikes collaborates with researchers including Umesh D. Wankhade, Henry A. Paz, Craig Porter, and D Sadler. He has authored 48 publications with 797 citations and an h-index of 12.
Metrics
- h-index: 12
- Publications: 49
- Citations: 799
Selected Publications
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The Transgenerational Inheritance of Obesity: Maternal High-Fat Diet Drives Inflammatory Transcriptomic Signatures in Offspring Adipose Tissue (2025)
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Western Diet Modifies Platelet Activation Profiles in Male Mice (2024)
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Parental cardiorespiratory fitness influences early life energetics and metabolic health (2023)
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A modest change in housing temperature alters whole body energy expenditure and adipocyte thermogenic capacity in mice (2022)
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Gut Microbiome and Metabolome Modulation by Maternal High-Fat Diet and Thermogenic Challenge (2022)
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