Match tier Listed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-10-05

Ashley Herdman

PhD Candidate

2 h-index 10 pubs 20 cited

  • Pituitary Gland
  • Animals
  • Female
  • Mice
  • Diet, High-Fat
  • Somatotrophs
  • Receptors, Leptin
  • Aging
  • Mice, Inbred C57BL
  • Signal Transduction
  • Leptin
  • Transcriptome
  • Male
  • Obesity
  • Gene Expression Profiling

Biography and Research Information

OverviewAI-generated summary

Ashley Herdman's research investigates the impact of diet and aging on the pituitary gland, particularly focusing on the role of leptin receptor signaling in somatotropes. Herdman's work has explored how high-fat diets influence anterior pituitary transcriptomics, with an emphasis on oxidative stress and cell metabolism. Further studies examine the consequences of ablating leptin receptor signaling in female mice, revealing alterations in somatotrope transcriptome maturation and pituitary plasticity in aging animals. Herdman has also investigated gonadotrope remodeling in states of sustained low estrogen and the influence of secretoneurin on luteinizing hormone secretion. Collaborations include extensive work with Angela K. Odle, Melanie C MacNicol, Angus M. MacNicol, and Alex Lagasse at the University of Arkansas for Medical Sciences, with whom Herdman shares nine publications.

Metrics

  • h-index: 2
  • Publications: 10
  • Citations: 20

Positions

  • PhD Candidate 2020–present
    University of Arkansas for Medical Sciences Department of Neuroscience ORCID

Selected Publications

  • Gonadotrope remodeling in sustained low estrogen states: single-cell transcriptomic analysis reveals gonadotrope subtypes and activation of stem cell populations (2026)
    Biology of Reproduction 1 citation DOI OpenAlex
  • Secretogranin II–derived peptide secretoneurin differentially stimulates luteinizing hormone secretion by age and sex in ex vivo murine pituitaries (2026)
    Biology of Reproduction DOI OpenAlex
  • OR13-08 Secretoneurin Modulates Gonadotrope Function Cyclically to Regulate LH Secretion (2025)
    Journal of the Endocrine Society DOI OpenAlex
  • SAT-001 Impact of VCD-induced Menopause on Gonadotrope Transcriptomics Reveals Estrogen-dependent Genes in the GnRH Signaling Pathway (2025)
    Journal of the Endocrine Society DOI OpenAlex
  • High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes (2025)
    Frontiers in Endocrinology 2 citations DOI OpenAlex
  • Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice (2025)
    Endocrinology 5 citations DOI OpenAlex
  • 8649 Ablation of Leptin Receptors in Somatotropes Impacts Transcriptomic Plasticity in the Pou1f1 Lineage of Female Pituitary Cells (2024)
    Journal of the Endocrine Society DOI OpenAlex
  • Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism (2023)
    Endocrinology 12 citations DOI OpenAlex
  • FRI290 Proteomic Identification Of Secretoneurin-Stimulated Proteins In Purified Mouse Gonadotropes (2023)
    Journal of the Endocrine Society DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

17 Collaborators 4 Institutions 2 Countries

Top Collaborators

View profile →
View profile →
View profile →
View profile →
View profile →
View profile →
View profile →
View profile →

Similar Researchers

Based on overlapping research topics