Toby L. Chambers

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Post-Doctoral Research Scholar

University of Arkansas

Also affiliated: Ball State University (2019–2026); University of Central Missouri (2015–2016); Oklahoma Medical Research Foundation (2001); University of Oklahoma Health Sciences Center (2001); Stanford University (2022)

Postdoc Researcher

12 h-index 44 pubs 960 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website Research Group

OverviewAI-generated summary

Toby L. Chambers investigates the molecular and epigenetic signatures associated with exercise training and aging in skeletal muscle. Their work examines how different types of exercise, particularly endurance training, influence gene expression and DNA methylation patterns across various tissues in both animal models and human subjects. Recent publications have explored the temporal dynamics of multi-omic responses to exercise, the role of specific genes like MYC in muscle growth, and the integration of methylome and proteome data to understand skeletal muscle health in aging populations. Chambers has also studied the effects of senolytic administration on DNA methylation clocks and the methylome in aged skeletal muscle. Their research contributes to understanding the complex interplay between physical activity, epigenetics, and age-related physiological changes.

Metrics

h-index: 12
Publications: 44
Citations: 960

Selected Publications

Transient MYC Mimicking the Exercise Response Orchestrates Multifaceted Skeletal Muscle Adaptations (2026)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Ribosome dynamics during skeletal muscle repair and regeneration in mice and humans (2026)

American Journal of Physiology-Cell Physiology 1 citation DOI OpenAlex
Mitochondrial capacities and quality control following short‐ and long‐term weight restoration after simulated anorexia nervosa (2025)

Experimental Physiology 2 citations DOI OpenAlex
Regenerate to “Rejuvenate”: Insights From Adult Resident Stem Cells of Aged Flatworms and Mice (2025)

Aging Cell 1 citation DOI OpenAlex
Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females (2025)

BMC Cancer 5 citations DOI OpenAlex
Consensus Statements—Optimizing Performance of the Elite Athlete (2025)

Scandinavian Journal of Medicine and Science in Sports 11 citations DOI OpenAlex
Global mitophagy inhibition via BNIP3 ablation is not sufficient to alleviate skeletal muscle impairments in male and female tumor-bearing mice (2025)

Journal of Applied Physiology 5 citations DOI OpenAlex
A history of omics discoveries reveals the correlates and mechanisms of loading-induced hypertrophy in adult skeletal muscle. 2024 CaMPS young investigator award invited review (2025)

American Journal of Physiology-Cell Physiology 10 citations DOI OpenAlex
A satellite cell‐dependent epigenetic fingerprint in skeletal muscle identity genes after lifelong physical activity (2025)

The FASEB Journal 10 citations DOI OpenAlex
The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth (2024)

EMBO Reports 28 citations DOI OpenAlex
Methylome–proteome integration after late‐life voluntary exercise training reveals regulation and target information for improved skeletal muscle health (2024)

The Journal of Physiology 26 citations DOI OpenAlex