Match tier
Likely match
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-08-20
S
Seongkyun Lim
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Research Assistant
Also affiliated: East Carolina University (2018); UCLA Health (2023); Korea Institute of Oriental Medicine (2023)
Graduate Student Researcher
12 h-index
42 pubs
477 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Seongkyun Lim's research focuses on skeletal muscle physiology, particularly in the context of aging, disuse atrophy, and cancer cachexia. Lim has investigated the molecular mechanisms underlying muscle growth following stimuli and has explored sex-based differences in the development of disuse atrophy, observing potentially exacerbated catabolic signaling in female mice.
Further research by Lim examines the metabolic and contractile alterations associated with cancer cachexia in female tumor-bearing mice. This work has identified distinct biphasic transcriptional disruptions in female skeletal muscle compared to males during cancer cachexia progression. Lim has also studied the role of mitochondrial aberrations in disuse atrophy and cancer cachexia, noting differential effects between male and female mice. Recent work has explored the potential of the mitochondrial antioxidant SkQ1 to attenuate muscle wasting and improve contractility in mouse models of cancer cachexia.
Lim has co-authored 42 publications with an h-index of 12 and 465 citations. Lim has served as a Co-Principal Investigator on two NSF grants totaling $775,000, focusing on the dynamic modeling of river ecosystem stability and its relation to cultural resiliency.
Metrics
- h-index: 12
- Publications: 42
- Citations: 477
Selected Publications
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Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females (2025)
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Global mitophagy inhibition via BNIP3 ablation is not sufficient to alleviate skeletal muscle impairments in male and female tumor-bearing mice (2025)
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Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice (2024)
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Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia (2023)
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The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males (2023)
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Development of skeletal muscle fibrosis in a rodent model of cancer cachexia (2023)
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MicroRNA control of the myogenic cell transcriptome and proteome: the role of miR-16 (2023)
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Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia (2023)
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A molecular signature defining exercise adaptation with ageing and <i>in vivo</i> partial reprogramming in skeletal muscle (2022)
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The Time-Course of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions in Female Skeletal Muscle Distinct from Males (2022)
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Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks (2022)
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Differential Induction Of Regulators Of Protein Turnover During C26-induced Cancer Cachexia Between Biological Sexes (2022)
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Males, But Not Females, Demonstrate Mitochondrial Dysfunction In The C26 Model Of Cancer Cachexia (2022)
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PGC-1α overexpression is not sufficient to mitigate cancer cachexia in either male or female mice (2022)
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Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner (2022)
Federal Grants 2 $775,000 total
NSF
Co-PI
Oct 2025 - Aug 2027
SCC-CIVIC-FA Track A: Dynamic Modeling of River Ecosystem Stability
NSF
Co-PI
Oct 2024 - Jun 2025
Collaboration Network
Top Collaborators
Nicholas P. Greene
University of Arkansas at Fayetteville
17 shared publications
In database
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- A molecular signature defining exercise adaptation with ageing and <i>in vivo</i> partial reprogramming in skeletal muscle
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
Showing 5 of 17 shared publications
Tyrone A. Washington
University of Arkansas at Fayetteville
15 shared publications
In database
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
Showing 5 of 15 shared publications
Francielly Morena da Silva
University of Arkansas at Fayetteville
13 shared publications
In database
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- A molecular signature defining exercise adaptation with ageing and <i>in vivo</i> partial reprogramming in skeletal muscle
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
Showing 5 of 13 shared publications
Eleanor R. Schrems
University of Arkansas at Fayetteville
12 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice
Showing 5 of 12 shared publications
Ana Regina Cabrera
University of Arkansas at Fayetteville
11 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice
Showing 5 of 11 shared publications
Megan E. Rosa‐Caldwell
Beth Israel Deaconess Medical Center
10 shared publications
In database
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
Showing 5 of 10 shared publications
Kevin A. Murach
University of Arkansas at Fayetteville
7 shared publications
In database
- A molecular signature defining exercise adaptation with ageing and <i>in vivo</i> partial reprogramming in skeletal muscle
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
- Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice
- MicroRNA control of the myogenic cell transcriptome and proteome: the role of miR-16
- Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females
Showing 5 of 7 shared publications
J. William Deaver
Vanderbilt University (US)
6 shared publications
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Males, But Not Females, Demonstrate Mitochondrial Dysfunction In The C26 Model Of Cancer Cachexia
Showing 5 of 6 shared publications
Landen W. Saling
University of Arkansas at Fayetteville
6 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Differential Induction Of Regulators Of Protein Turnover During C26-induced Cancer Cachexia Between Biological Sexes
Showing 5 of 6 shared publications
Jacob L. Brown
University of Arkansas at Fayetteville (US)
5 shared publications
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- PGC-1α overexpression is not sufficient to mitigate cancer cachexia in either male or female mice
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia
David E. Lee
University of Arkansas at Fayetteville (US)
5 shared publications
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- MicroRNA control of the myogenic cell transcriptome and proteome: the role of miR-16
Michael P. Wiggs
Baylor University (US)
5 shared publications
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Males, But Not Females, Demonstrate Mitochondrial Dysfunction In The C26 Model Of Cancer Cachexia
Wesley S. Haynie
University of Arkansas at Fayetteville
4 shared publications
In database
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia
Sabin Khadgi
University of Arkansas at Fayetteville
4 shared publications
In database
- A molecular signature defining exercise adaptation with ageing and <i>in vivo</i> partial reprogramming in skeletal muscle
- Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice
- Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females
- Global mitophagy inhibition via BNIP3 ablation is not sufficient to alleviate skeletal muscle impairments in male and female tumor-bearing mice
Stavroula Tsitkanou
University of Arkansas at Fayetteville
4 shared publications
In database
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice
- Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females
- Global mitophagy inhibition via BNIP3 ablation is not sufficient to alleviate skeletal muscle impairments in male and female tumor-bearing mice
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