Sonu Pahal

Researcher

University of Arkansas for Medical Sciences

faculty

6 h-index 14 pubs 92 cited

Research Areas

Neuroscience and Neuropharmacology Research Neurological disorders and treatments Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments Parkinson's Disease Mechanisms and Treatments Phytochemicals and Antioxidant Activities Computational Drug Discovery Methods Bioinformatics and Genomic Networks

Links

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OverviewAI-generated summary

Sonu Pahal's research focuses on neurodegenerative disorders, particularly Alzheimer's and Parkinson's diseases, and their potential therapeutic targets. Pahal has investigated the role of natural compounds, such as those found in *Withania somnifera*, and pharmaceutical agents like ezetimibe, in modulating disease mechanisms. Studies include network pharmacological evaluations to identify bioactive phytochemicals and *in silico* approaches to target specific receptors and interactions, such as the 14-3-3G::Hexokinase interaction implicated in Alzheimer's disease. Research also extends to exploring targets for other neurological conditions, including Amyotrophic Lateral Sclerosis and oligodendrocyte myelin glycoprotein (OMgp) in neuronal repair and regeneration. Pahal's work involves collaborations with researchers at the University of Arkansas for Medical Sciences, including Meenakshisundaram Balasubramaniam and Srinivas Ayyadevara. With a publication record of 14 papers and 92 citations, Pahal has an h-index of 6.

Metrics

  • h-index: 6
  • Publications: 14
  • Citations: 92

Selected Publications

  • The aggregate proteome of Caenorhabditis elegans mitochondria implicates shared mechanisms of aging and Alzheimer’s disease (2026) DOI
  • Role of Monoclonal Antibodies in Alzheimer’s Disease: Successes, Failures, and Future Directions (2025) DOI
  • Altered protein homeostasis in cardiovascular diseases contributes to Alzheimer’s-like neuropathology (2025) DOI
  • From data to discovery: Neuroinformatics in understanding Alzheimer's disease (2024) DOI
  • Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction (2024) DOI

Collaborators

Researchers in the database who share publications

Meenakshisundaram Balasubramaniam University of Arkansas for Medical Sciences 6 shared publications Srinivas Ayyadevara University of Arkansas for Medical Sciences 5 shared publications Robert J. Shmookler Reis University of Arkansas for Medical Sciences 4 shared publications Nirjal Mainali University of Arkansas for Medical Sciences 4 shared publications Akshatha Ganne University of Arkansas for Medical Sciences 3 shared publications Corey Nagel University of Arkansas for Medical Sciences 1 shared publication Srikanth Vallurupalli University of Arkansas for Medical Sciences 1 shared publication Joseph Asante University of Arkansas at Little Rock 1 shared publication

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