Umesh D. Wankhade
Post Doctoral Researcher
Also affiliated: National Institutes of Health (2017); Arkansas Children's Hospital (2018–2025); Indian Veterinary Research Institute (2008); University of Arkansas Medical Center (2016–2022); National Institute of Diabetes and Digestive and Kidney Diseases (2014–2018); Arkansas Children's Nutrition Center (2016–2026); Arkansas Department of Agriculture (2017); Virginia Tech (2007–2012)
Postdoc Researcher
Peds Pediatrics, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Umesh D. Wankhade's research focuses on the intersection of diet, gut microbiota, and metabolic health, primarily utilizing mouse models. His work has investigated how specific dietary interventions, such as tryptophan deficiency or blueberry consumption, impact gut microbial composition and function, leading to changes in systemic inflammation, insulin resistance, and vascular complications.
Wankhade has also explored the role of specific molecular pathways and metabolites in metabolic regulation. His research includes examining how compounds like hippuric acid influence bone resorption and how the fungus Cordyceps affects ceramide biosynthesis and hepatic steatosis. Furthermore, his work has touched upon the potential roles of proteins like globins in adipose tissue function and the gut microbiota's connection to neurodegenerative diseases like Alzheimer's.
With an h-index of 24 and over 80 publications, Wankhade is recognized as a highly cited researcher. He collaborates extensively with colleagues at the University of Arkansas for Medical Sciences, including Henry A. Paz, Sree V. Chintapalli, and James D. Sikes, and leads a research group.
Metrics
- h-index: 24
- Publications: 82
- Citations: 1,923
Selected Publications
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Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression (2026)
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Hormones, heat, and health: a comprehensive review of sex-based differences in brown and beige fat biology (2025)
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Dietary Prebiotics Modulate Omeprazole‐Induced Alterations in the Gut Microbial Signature (2025)
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Impact of short-term housing temperature alteration on metabolic parameters and adipose tissue in female mice (2025)
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Shared and distinct adaptations to early‐life exercise training based on inborn fitness (2025)
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Maternal high-fat diet-induced obesity in offspring: Unraveling adipose tissue dysfunction mediated by increased heat shock proteins (2025)
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The Transgenerational Inheritance of Obesity: Maternal High-Fat Diet Drives Inflammatory Transcriptomic Signatures in Offspring Adipose Tissue (2025)
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Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation (2025)
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Gut microbes metabolize strawberry phytochemicals and mediate their beneficial effects on vascular inflammation (2025)
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Shared and distinct adaptations to early-life exercise training based on inborn fitness (2024)
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Impact of maternal high‐fat diet on offspring gut microbiota during short‐term high‐fat diet exposure in mice (2024)
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Maternal High-Fat Diet-Induced Obesity in Offspring: Unraveling Adipose Tissue Dysfunction Mediated by Increased Heat Shock Proteins (2024)
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Maternal Obesity Alters Adipogenic Potential and Mitochondrial Function in Mesenchymal Stem Cells From Infants Born to Mothers With Overweight or Obesity (2024)
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Effects of Statin and Annatto-extracted Tocotrienol Supplementation on Glucose Homeostasis, Bone Microstructure, and Gut Microbiota Composition in Obese Mice (2024)
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Gut Microbiota Depletion Using Antibiotics to Investigate Diet‐Derived Microbial Metabolites: An Efficient Strategy (2023)
Collaboration Network
Top Collaborators
- Beige Adipose Tissue Identification and Marker Specificity—Overview
- Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis
- Dietary Blueberry Ameliorates Vascular Complications in Diabetic Mice Possibly through NOX4 and Modulates Composition and Functional Diversity of Gut Microbes
- Blueberry intervention mitigates detrimental microbial metabolite trimethylamine N‐oxide by modulating gut microbes
- Gut Microbiota Depletion Using Antibiotics to Investigate Diet‐Derived Microbial Metabolites: An Efficient Strategy
Showing 5 of 16 shared publications
- Gut Microbiota Depletion Using Antibiotics to Investigate Diet‐Derived Microbial Metabolites: An Efficient Strategy
- Dose- and Time-Dependent Effect of Dietary Blueberries on Diabetic Vasculature Is Correlated with Gut Microbial Signature
- Impact of maternal high‐fat diet on offspring gut microbiota during short‐term high‐fat diet exposure in mice
- Gut microbes metabolize strawberry phytochemicals and mediate their beneficial effects on vascular inflammation
- Gut Microbiome and Metabolome Modulation by Maternal High-Fat Diet and Thermogenic Challenge
Showing 5 of 11 shared publications
- Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis
- Dietary Blueberry Ameliorates Vascular Complications in Diabetic Mice Possibly through NOX4 and Modulates Composition and Functional Diversity of Gut Microbes
- Blueberry intervention mitigates detrimental microbial metabolite trimethylamine N‐oxide by modulating gut microbes
- Gut Microbes Are Associated with the Vascular Beneficial Effects of Dietary Strawberry on Metabolic Syndrome‐Induced Vascular Inflammation
- Gut Microbiota Depletion Using Antibiotics to Investigate Diet‐Derived Microbial Metabolites: An Efficient Strategy
Showing 5 of 8 shared publications
- Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis
- Dietary Blueberry Ameliorates Vascular Complications in Diabetic Mice Possibly through NOX4 and Modulates Composition and Functional Diversity of Gut Microbes
- Blueberry intervention mitigates detrimental microbial metabolite trimethylamine N‐oxide by modulating gut microbes
- Gut Microbes Are Associated with the Vascular Beneficial Effects of Dietary Strawberry on Metabolic Syndrome‐Induced Vascular Inflammation
- Gut Microbiota Depletion Using Antibiotics to Investigate Diet‐Derived Microbial Metabolites: An Efficient Strategy
Showing 5 of 8 shared publications
- Impact of maternal high‐fat diet on offspring gut microbiota during short‐term high‐fat diet exposure in mice
- Gut Microbiome and Metabolome Modulation by Maternal High-Fat Diet and Thermogenic Challenge
- Maternal high-fat diet-induced obesity in offspring: Unraveling adipose tissue dysfunction mediated by increased heat shock proteins
- Shared and distinct adaptations to early‐life exercise training based on inborn fitness
- Maternal High-Fat Diet-Induced Obesity in Offspring: Unraveling Adipose Tissue Dysfunction Mediated by Increased Heat Shock Proteins
Showing 5 of 8 shared publications
- GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice
- Dietary Blueberry Ameliorates Vascular Complications in Diabetic Mice Possibly through NOX4 and Modulates Composition and Functional Diversity of Gut Microbes
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- Gut microbes metabolize strawberry phytochemicals and mediate their beneficial effects on vascular inflammation
- <scp>Short‐Term</scp> Increased Physical Activity During Early Life Affects High‐Fat <scp>Diet–Induced</scp> Bone Loss in Young Adult Mice
Showing 5 of 7 shared publications
- GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice
- Dietary Blueberry Ameliorates Vascular Complications in Diabetic Mice Possibly through NOX4 and Modulates Composition and Functional Diversity of Gut Microbes
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Gut Microbes Are Associated with the Vascular Beneficial Effects of Dietary Strawberry on Metabolic Syndrome‐Induced Vascular Inflammation
- Gut Microbiome and Metabolome Modulation by Maternal High-Fat Diet and Thermogenic Challenge
Showing 5 of 6 shared publications
- Dietary Blueberry Ameliorates Vascular Complications in Diabetic Mice Possibly through NOX4 and Modulates Composition and Functional Diversity of Gut Microbes
- Blueberry intervention mitigates detrimental microbial metabolite trimethylamine N‐oxide by modulating gut microbes
- Gut Microbes Are Associated with the Vascular Beneficial Effects of Dietary Strawberry on Metabolic Syndrome‐Induced Vascular Inflammation
- Gut Microbiota Depletion Using Antibiotics to Investigate Diet‐Derived Microbial Metabolites: An Efficient Strategy
- Dose- and Time-Dependent Effect of Dietary Blueberries on Diabetic Vasculature Is Correlated with Gut Microbial Signature
Showing 5 of 6 shared publications
- Beige Adipose Tissue Identification and Marker Specificity—Overview
- Gut Microbiome and Metabolome Modulation by Maternal High-Fat Diet and Thermogenic Challenge
- Beta‐adrenergic agonist induces unique transcriptomic signature in inguinal white adipose tissue
- Maternal High-Fat Diet-Induced Obesity in Offspring: Unraveling Adipose Tissue Dysfunction Mediated by Increased Heat Shock Proteins
- Effects of Statin and Annatto-extracted Tocotrienol Supplementation on Glucose Homeostasis, Bone Microstructure, and Gut Microbiota Composition in Obese Mice
- Maternal high-fat diet-induced obesity in offspring: Unraveling adipose tissue dysfunction mediated by increased heat shock proteins
- Maternal Obesity Alters Adipogenic Potential and Mitochondrial Function in Mesenchymal Stem Cells From Infants Born to Mothers With Overweight or Obesity
- Maternal High-Fat Diet-Induced Obesity in Offspring: Unraveling Adipose Tissue Dysfunction Mediated by Increased Heat Shock Proteins
- Impact of maternal high‐fat diet on offspring gut microbiota during short‐term high‐fat diet exposure in mice
- Maternal high-fat diet-induced obesity in offspring: Unraveling adipose tissue dysfunction mediated by increased heat shock proteins
- Maternal High-Fat Diet-Induced Obesity in Offspring: Unraveling Adipose Tissue Dysfunction Mediated by Increased Heat Shock Proteins
- Impact of short-term housing temperature alteration on metabolic parameters and adipose tissue in female mice
- Maternal high-fat diet-induced obesity in offspring: Unraveling adipose tissue dysfunction mediated by increased heat shock proteins
- Shared and distinct adaptations to early‐life exercise training based on inborn fitness
- Maternal High-Fat Diet-Induced Obesity in Offspring: Unraveling Adipose Tissue Dysfunction Mediated by Increased Heat Shock Proteins
- Shared and distinct adaptations to early-life exercise training based on inborn fitness
- GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- <scp>Short‐Term</scp> Increased Physical Activity During Early Life Affects High‐Fat <scp>Diet–Induced</scp> Bone Loss in Young Adult Mice
- GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- <scp>Short‐Term</scp> Increased Physical Activity During Early Life Affects High‐Fat <scp>Diet–Induced</scp> Bone Loss in Young Adult Mice
- On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice
- Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice
- <scp>Short‐Term</scp> Increased Physical Activity During Early Life Affects High‐Fat <scp>Diet–Induced</scp> Bone Loss in Young Adult Mice
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