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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-15

Shuoqiu Deng

Researcher

Also affiliated: Arkansas Children's Hospital (2026); Nanjing University of Chinese Medicine (2019); Chinese Academy of Medical Sciences & Peking Union Medical College (2020–2026); University of Arkansas Medical Center (2025); China Academy of Chinese Medical Sciences (2020–2025); Arkansas Children's Nutrition Center (2026)

Faculty Researcher

5 h-index 33 pubs 98 cited

  • Animals
  • Humans
  • Malaria, Cerebral
  • Cardiovascular Diseases
  • Artesunate
  • Particulate Matter
  • Neuroprotective Agents
  • Antimalarials
  • Artemisinins
  • Male
  • Pyrazines
  • NLR Family, Pyrin Domain-Containing 3 Protein
  • Inflammation
  • Rats, Sprague-Dawley
  • Rats

Biography and Research Information

OverviewAI-generated summary

Shuoqiu Deng's research investigates the pharmacological effects of traditional Chinese medicine and specific compounds on cardiovascular and neurological conditions. Deng has published work on the protective mechanisms of Shengmai formula and Shenlian extract against myocardial injury induced by particulate matter and ischemia, often involving pathways such as PI3K/AKT/p38 MAPK/Nrf2 and NLRP3 inflammasomes. Other research areas include the effects of artesunate and tetramethylpyrazine on experimental cerebral malaria and ischemic stroke, focusing on mechanisms like protein S-nitrosylation and blood-brain barrier preservation. Deng also explores pharmacotherapeutic strategies for particulate matter-induced lung and cardiovascular damage and has reviewed cardiovascular complications in malaria. Collaborations include work with Christoph Mora, Yunmeng Liu, Katherine Deck, and Pamela I. Rogers at the University of Arkansas for Medical Sciences.

Metrics

  • h-index: 5
  • Publications: 33
  • Citations: 98

Selected Publications

  • Macrophage Plasticity Drives Cardiac Dysfunction in Hypertension 2253031 (2026)
    The Journal of Immunology DOI OpenAlex
  • Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853 (2026)
    The Journal of Immunology DOI OpenAlex
  • Kidney Resident Memory CD8+ T cells drive the immortality of hypertension (2026)
    Physiology DOI OpenAlex
  • Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension (2026)
    Physiology DOI OpenAlex
  • IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287 (2025)
    The Journal of Immunology DOI OpenAlex
  • P2X7 Drives T-cell Activation Promoting Chronic Inflammation During High Blood Pressure 9289 (2025)
    The Journal of Immunology DOI OpenAlex
  • Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288 (2025)
    The Journal of Immunology DOI OpenAlex
  • Energy Overload: ATP-P2X7-Mediated T Cell Activation in Obesity-Induced Type 2 Diabetes 9286 (2025)
    The Journal of Immunology DOI OpenAlex
  • Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension (2025)
    Journal of the American Society of Nephrology DOI OpenAlex
  • Uncovering immune pathways for therapeutic targeting of hypertension (2025)
    Expert Opinion on Therapeutic Targets 1 citation DOI OpenAlex
  • Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications (2025)
    Life 2 citations DOI OpenAlex
  • Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction (2025)
    Physiology DOI OpenAlex
  • Establishment of resident memory T cells anchors hypertension in the kidney (2025)
    Physiology DOI OpenAlex
  • SS-31 Attenuates Doxorubicin-induced Cardiomyoblast H9C2 Cell Senescence (2024)
    Journal of Pharmacology and Experimental Therapeutics DOI OpenAlex

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Collaboration Network

17 Collaborators 3 Institutions 2 Countries

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