Sarita Garg
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Also affiliated: Arkansas Children's Hospital (2002–2007); University of Arkansas Medical Center (2014); Arkansas Children's Research Institute (2004–2007)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Sarita Garg's research investigates the biological impacts of various stressors and interventions, with a focus on cellular and physiological responses. Her work has explored the effects of total-body irradiation on immune cell populations within the intestinal mucosa and the potential radioprotective properties of compounds like pentoxifylline and γ-tocotrienol. Garg has also studied the role of specific dietary components, such as methionine, in modulating gut metabolism, microbiome profiles, and barrier function in mice. Additionally, her research has examined the neuroprotective effects of ketamine in models of inflammatory pain in newborn rats and the involvement of toll-like receptor 2 in brain abscesses induced by Staphylococcus aureus.
Garg's scholarly contributions are reflected in her h-index of 19 and over 1,100 citations across 49 publications. She has a history of collaboration with researchers at the University of Arkansas for Medical Sciences, including Isabelle R. Miousse, Alan J. Tackett, Lauren C. Morehead, and Martin Hauer-Jensen, with whom she shares multiple publications.
Metrics
- h-index: 19
- Publications: 43
- Citations: 1,090
Selected Publications
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DZNep : A Methyltransferase Modulator for Disease Mitigation (2026)
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Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction (2025)
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Rescue of Methionine Dependence by Cobalamin in a Human Colorectal Cancer Cell Line (2024)
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Modulation of Hematopoietic Injury by a Promising Radioprotector, Gamma-Tocotrienol, in Rhesus Macaques Exposed to Partial-Body Radiation (2023)
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Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma (2023)
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Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model (2023)
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Characterization of methionine dependence in melanoma cells (2023)
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Increased response to immune checkpoint inhibitors with dietary methionine restriction (2023)
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Characterization of methionine dependence in melanoma cells (2023)
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Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer (2023)
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Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction (2023)
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Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model (2022)
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Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model (2022)
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Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate (2022)
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Dietary Methionine Deficiency Enhances Genetic Instability in Murine Immune Cells (2021)
Collaboration Network
Top Collaborators
- Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology
- Influence of Sublethal Total-Body Irradiation on Immune Cell Populations in the Intestinal Mucosa
- Pentoxifylline Enhances the Radioprotective Properties of γ-Tocotrienol: Differential Effects on the Hematopoietic, Gastrointestinal and Vascular Systems
- Procalcitonin as a Predictive Biomarker for Total Body Irradiation–Induced Bacterial Load and Lethality in Mice
- Segmental Differences in Radiation-Induced Alterations of Tight Junction-Related Proteins in Non-Human Primate Jejunum, Ileum and Colon
Showing 5 of 20 shared publications
- Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model
- Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate
- Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome
- Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model
Showing 5 of 17 shared publications
- Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology
- Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome
- Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses
- Simultaneous exposure to chronic irradiation and simulated microgravity differentially alters immune cell phenotype in mouse thymus and spleen
- Gamma-Tocotrienol Protects the Intestine from Radiation Potentially by Accelerating Mesenchymal Immune Cell Recovery
Showing 5 of 8 shared publications
- Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model
- Characterization of methionine dependence in melanoma cells
- Increased response to immune checkpoint inhibitors with dietary methionine restriction
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction
Showing 5 of 8 shared publications
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model
- Characterization of methionine dependence in melanoma cells
- Increased response to immune checkpoint inhibitors with dietary methionine restriction
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction
- Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma
Showing 5 of 6 shared publications
- Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses
- Simultaneous exposure to chronic irradiation and simulated microgravity differentially alters immune cell phenotype in mouse thymus and spleen
- Gamma-Tocotrienol Protects the Intestine from Radiation Potentially by Accelerating Mesenchymal Immune Cell Recovery
- De Novo Biosynthesis of Tetrahydrobiopterin is Critical in Protecting against Ionizing Radiation
- Influence of Sublethal Total-Body Irradiation on Immune Cell Populations in the Intestinal Mucosa
- Pentoxifylline Enhances the Radioprotective Properties of γ-Tocotrienol: Differential Effects on the Hematopoietic, Gastrointestinal and Vascular Systems
- Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses
- De Novo Biosynthesis of Tetrahydrobiopterin is Critical in Protecting against Ionizing Radiation
- Procalcitonin as a Predictive Biomarker for Total Body Irradiation–Induced Bacterial Load and Lethality in Mice
- Bone Marrow Transplantation Helps Restore the Intestinal Mucosal Barrier after Total Body Irradiation in Mice
- Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses
- De Novo Biosynthesis of Tetrahydrobiopterin is Critical in Protecting against Ionizing Radiation
- Influence of Sublethal Total-Body Irradiation on Immune Cell Populations in the Intestinal Mucosa
- Bone Marrow Transplantation Helps Restore the Intestinal Mucosal Barrier after Total Body Irradiation in Mice
- Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses
- Simultaneous exposure to chronic irradiation and simulated microgravity differentially alters immune cell phenotype in mouse thymus and spleen
- Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses
- Recombinant Thrombomodulin (Solulin) Ameliorates Early Intestinal Radiation Toxicity in a Preclinical Rat Model
- Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
- Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate
- Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model
- Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model
- Modulation of Hematopoietic Injury by a Promising Radioprotector, Gamma-Tocotrienol, in Rhesus Macaques Exposed to Partial-Body Radiation
- Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate
- Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model
- Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model
- Modulation of Hematopoietic Injury by a Promising Radioprotector, Gamma-Tocotrienol, in Rhesus Macaques Exposed to Partial-Body Radiation
- Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate
- Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model
- Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model
- Modulation of Hematopoietic Injury by a Promising Radioprotector, Gamma-Tocotrienol, in Rhesus Macaques Exposed to Partial-Body Radiation
- Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate
- Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model
- Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model
- Modulation of Hematopoietic Injury by a Promising Radioprotector, Gamma-Tocotrienol, in Rhesus Macaques Exposed to Partial-Body Radiation
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model
- Increased response to immune checkpoint inhibitors with dietary methionine restriction
- Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction
- Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma
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