Match tier
Listed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
Q
Qiang Fu
High Impact
Assistant Research Professor
Also affiliated: National Institutes of Health (2007); University of Arkansas Medical Center (2023); Central Arkansas Veterans Healthcare System (2003–2011)
Internal Med, College of Medicine
25 h-index
41 pubs
2,843 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Qiang Fu studies the molecular mechanisms underlying radiation injury and the development of protective or therapeutic strategies. His research has investigated the effects of total-body irradiation on the gastrointestinal tract, focusing on mechanisms such as endothelial dysfunction and oxidative stress. Fu has explored the potential of pharmacological agents, including γ-tocotrienol and compounds targeting the thrombomodulin–activated protein C pathway, to ameliorate radiation toxicity. His work also examines the role of parathyroid hormone in bone biology, specifically its influence on osteoblastogenesis and sclerostin expression in osteocytes, as well as its signaling pathways in osteoblasts.
Fu's publications include investigations into the proteasomal degradation of Runx2 and its impact on anti-apoptotic signaling in osteoblasts, and the control of receptor activator of NF-κB ligand gene expression. He has also conducted comparative gene expression profiling in human cell lines treated with inhibitors of Rho kinase or atorvastatin. His research network includes collaborations with colleagues such as Ha-Neui Kim, Charles A. O’Brien, Melda Onal, and Maria Almeida at the University of Arkansas for Medical Sciences. Fu has an h-index of 25 and over 2,800 citations across his 61 publications.
Metrics
- h-index: 25
- Publications: 41
- Citations: 2,843
Positions
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UAMS Medical Center 2014–presentORCID
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Assistant Research Professor publications 2003–2025University of Arkansas for Medical Sciences Internal Med, College of Medicine Institutional directory
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Jiangsu Institute of Nuclear Medicine 2009–2013ORCID
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Fudan University 1996–2000ORCID
Selected Publications
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Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells (2025)
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Potent suppression of bone remodeling by denosumab does not blunt the anabolic response to romosozumab in mice (2025)
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Sirtuin-3 promotes osteoclast maturation and bone loss by regulating mitochondrial ROS production during ionizing radiation exposure (2025)
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Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells (2025)
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Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness (2025)
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Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone (2024)
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A framework for defining mesenchymal cell types associated with murine periosteal and endosteal bone (2023)
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Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation (2023)
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A Rab33b missense mouse model for Smith-McCort dysplasia shows bone resorption defects and altered protein glycosylation (2023)
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Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass (2022)
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Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice (2022)
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Deuteration of the farnesyl terminal methyl groups of δ-tocotrienol and its effects on the metabolic stability and ability of inducing G-CSF production (2020)
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C/EBPδ protects from radiation-induced intestinal injury and sepsis by suppression of inflammatory and nitrosative stress (2019)
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The Role of Tetrahydrobiopterin (BH4) Bioavailability in Radiation-Induced Skin Injury (2015)
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Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses (2013)
Grants & Funding
As listed on this researcher's institutional profile.
- Synergistic Radioprotection of Gastrointestinal Tract by Gamma-Tocotrienol (GT3) and Statins: Efficacy and Mechanisms Uniformed Services University of the Health Sciences via Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Co-Investigator
- Evaluation of IPW-5371, a TGFRI kinase inhibitor, dosed as a single agent or in combination with G-CSF, as a medical countermeasure against the delayed effects of total body irradiation in mice - Continuation NIH/Nat. Inst. of Allergy & Infectious Diseases via Innovation Pathways Principal Investigator
- Osteocyte Control of Bone Remodeling NIH/Nat. Inst. of Arthritis & Musculoskeletal & Skin Diseases Principal Investigator
- Advanced Development of Gamma-Tocotrienol as a Radiation Countermeasure US Department of Defense via Armed Forces Radiobiology Research Institute Co-Investigator
- Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Principal Investigator
- Endonuclease-targeted radioprotection NIH/Nat. Inst. of Allergy & Infectious Diseases via Duke University Co-Investigator
Collaboration Network
Top Collaborators
Martin Hauer‐Jensen
University of Arkansas for Medical Sciences
16 shared publications
In database
- Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy
- Radiation damage to the gastrointestinal tract: mechanisms, diagnosis, and management
- γ-Tocotrienol Ameliorates Intestinal Radiation Injury and Reduces Vascular Oxidative Stress after Total-Body Irradiation by an HMG-CoA Reductase-Dependent Mechanism
- Pharmacological targeting of the thrombomodulin–activated protein C pathway mitigates radiation toxicity
- Radiation responses in skin and connective tissues: effect on wound healing and surgical outcome
Showing 5 of 16 shared publications
Charles A. O’Brien
University of Arkansas for Medical Sciences
13 shared publications
In database
- Chronic Elevation of Parathyroid Hormone in Mice Reduces Expression of Sclerostin by Osteocytes: A Novel Mechanism for Hormonal Control of Osteoblastogenesis
- Proteasomal Degradation of Runx2 Shortens Parathyroid Hormone-induced Anti-apoptotic Signaling in Osteoblasts
- Parathyroid Hormone Controls Receptor Activator of NF-κB Ligand Gene Expression via a Distant Transcriptional Enhancer
- Targeted Deletion of a Distant Transcriptional Enhancer of the Receptor Activator of Nuclear Factor-κB Ligand Gene Reduces Bone Remodeling and Increases Bone Mass
- IL-6 is not required for parathyroid hormone stimulation of RANKL expression, osteoclast formation, and bone loss in mice
Showing 5 of 13 shared publications
Marjan Boerma
National Institutes of Health
10 shared publications
In database
- Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy
- Radiation damage to the gastrointestinal tract: mechanisms, diagnosis, and management
- γ-Tocotrienol Ameliorates Intestinal Radiation Injury and Reduces Vascular Oxidative Stress after Total-Body Irradiation by an HMG-CoA Reductase-Dependent Mechanism
- Radiation responses in skin and connective tissues: effect on wound healing and surgical outcome
- Reduction of Radiation-Induced Vascular Nitrosative Stress by the Vitamin E Analog γ-Tocotrienol: Evidence of a Role for Tetrahydrobiopterin
Showing 5 of 10 shared publications
Maaike Berbée
Maastricht University (NL)
9 shared publications
- γ-Tocotrienol Ameliorates Intestinal Radiation Injury and Reduces Vascular Oxidative Stress after Total-Body Irradiation by an HMG-CoA Reductase-Dependent Mechanism
- Reduction of Radiation-Induced Vascular Nitrosative Stress by the Vitamin E Analog γ-Tocotrienol: Evidence of a Role for Tetrahydrobiopterin
- Pentoxifylline Enhances the Radioprotective Properties of γ-Tocotrienol: Differential Effects on the Hematopoietic, Gastrointestinal and Vascular Systems
- The Somatostatin Analog SOM230 (Pasireotide) Ameliorates Injury of the Intestinal Mucosa and Increases Survival after Total-Body Irradiation by Inhibiting Exocrine Pancreatic Secretion
- Mechanisms underlying the radioprotective properties of γ-tocotrienol: comparative gene expression profiling in tocol-treated endothelial cells
Showing 5 of 9 shared publications
Stavros C. Manolagas
Central Arkansas Veterans Healthcare System
7 shared publications
In database
- Chronic Elevation of Parathyroid Hormone in Mice Reduces Expression of Sclerostin by Osteocytes: A Novel Mechanism for Hormonal Control of Osteoblastogenesis
- Proteasomal Degradation of Runx2 Shortens Parathyroid Hormone-induced Anti-apoptotic Signaling in Osteoblasts
- Parathyroid Hormone Controls Receptor Activator of NF-κB Ligand Gene Expression via a Distant Transcriptional Enhancer
- Targeted Deletion of a Distant Transcriptional Enhancer of the Receptor Activator of Nuclear Factor-κB Ligand Gene Reduces Bone Remodeling and Increases Bone Mass
- IL-6 is not required for parathyroid hormone stimulation of RANKL expression, osteoclast formation, and bone loss in mice
Showing 5 of 7 shared publications
K. Sree Kumar
Uniformed Services University of the Health Sciences (US)
6 shared publications
- γ-Tocotrienol Ameliorates Intestinal Radiation Injury and Reduces Vascular Oxidative Stress after Total-Body Irradiation by an HMG-CoA Reductase-Dependent Mechanism
- Reduction of Radiation-Induced Vascular Nitrosative Stress by the Vitamin E Analog γ-Tocotrienol: Evidence of a Role for Tetrahydrobiopterin
- Influence of Sublethal Total-Body Irradiation on Immune Cell Populations in the Intestinal Mucosa
- Pentoxifylline Enhances the Radioprotective Properties of γ-Tocotrienol: Differential Effects on the Hematopoietic, Gastrointestinal and Vascular Systems
- Mechanisms underlying the radioprotective properties of γ-tocotrienol: comparative gene expression profiling in tocol-treated endothelial cells
Showing 5 of 6 shared publications
Ha‐Neui Kim
University of Arkansas for Medical Sciences
6 shared publications
In database
- Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone
- Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- Sirtuin-3 promotes osteoclast maturation and bone loss by regulating mitochondrial ROS production during ionizing radiation exposure
- A framework for defining mesenchymal cell types associated with murine periosteal and endosteal bone
Showing 5 of 6 shared publications
Melda Onal
University of Arkansas for Medical Sciences
5 shared publications
In database
- Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone
- The RANKL Distal Control Region Is Required for the Increase in RANKL Expression, But Not the Bone Loss, Associated with Hyperparathyroidism or Lactation in Adult Mice
- Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness
- A framework for defining mesenchymal cell types associated with murine periosteal and endosteal bone
Intawat Nookaew
University of Arkansas for Medical Sciences
5 shared publications
In database
- Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation
- Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- A framework for defining mesenchymal cell types associated with murine periosteal and endosteal bone
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
Maria Almeida
University of Arkansas for Medical Sciences
5 shared publications
In database
- Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness
- A framework for defining mesenchymal cell types associated with murine periosteal and endosteal bone
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
Snehalata A. Pawar
University of Arkansas for Medical Sciences (US)
4 shared publications
- Pharmacological targeting of the thrombomodulin–activated protein C pathway mitigates radiation toxicity
- C/EBPδ protects from radiation-induced intestinal injury and sepsis by suppression of inflammatory and nitrosative stress
- Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses
- De Novo Biosynthesis of Tetrahydrobiopterin is Critical in Protecting against Ionizing Radiation
Sarita Garg
University of Arkansas for Medical Sciences
4 shared publications
In database
- Influence of Sublethal Total-Body Irradiation on Immune Cell Populations in the Intestinal Mucosa
- Pentoxifylline Enhances the Radioprotective Properties of γ-Tocotrienol: Differential Effects on the Hematopoietic, Gastrointestinal and Vascular Systems
- Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses
- De Novo Biosynthesis of Tetrahydrobiopterin is Critical in Protecting against Ionizing Radiation
Kimberly J. Krager
University of Arkansas for Medical Sciences
4 shared publications
In database
- Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses
- Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
- De Novo Biosynthesis of Tetrahydrobiopterin is Critical in Protecting against Ionizing Radiation
- The Role of Tetrahydrobiopterin (BH4) Bioavailability in Radiation-Induced Skin Injury
Nükhet Aykin‐Burns
University of Arkansas for Medical Sciences
4 shared publications
In database
- Characterization of Transgenic Gfrp Knock-In Mice: Implications for Tetrahydrobiopterin in Modulation of Normal Tissue Radiation Responses
- Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
- Sirtuin-3 promotes osteoclast maturation and bone loss by regulating mitochondrial ROS production during ionizing radiation exposure
- The Role of Tetrahydrobiopterin (BH4) Bioavailability in Radiation-Induced Skin Injury
Robert S. Weinstein
University of Arkansas for Medical Sciences (US)
4 shared publications
- Proteasomal Degradation of Runx2 Shortens Parathyroid Hormone-induced Anti-apoptotic Signaling in Osteoblasts
- Targeted Deletion of a Distant Transcriptional Enhancer of the Receptor Activator of Nuclear Factor-κB Ligand Gene Reduces Bone Remodeling and Increases Bone Mass
- IL-6 is not required for parathyroid hormone stimulation of RANKL expression, osteoclast formation, and bone loss in mice
- The RANKL Distal Control Region Is Required for the Increase in RANKL Expression, But Not the Bone Loss, Associated with Hyperparathyroidism or Lactation in Adult Mice
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