Tiffany Weinkopff
Assistant Professor
Also affiliated: University of Maryland, Baltimore (2018); Centers for Disease Control and Prevention (2014); University of Georgia (2009–2014); University of Pennsylvania (2015–2016); University of Lausanne (2012–2015)
Faculty Researcher
Microbiology & Immunology, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Tiffany Weinkopff is an Assistant Professor in the Department of Microbiology & Immunology at the University of Arkansas for Medical Sciences. Her research focuses on understanding the host-pathogen interactions during parasitic infections, particularly cutaneous leishmaniasis. Weinkopff investigates how the host immune system responds to infection by *Leishmania major*, employing single-cell resolution techniques to analyze cellular heterogeneity and transcriptomic profiling in infected mice.
Her work has explored the role of signaling pathways, such as Hypoxia-Inducible Factor (HIF) signaling, in modulating macrophage function and promoting lymphangiogenesis during infection. She also studies the impact of the inflammatory microenvironment on macrophage transcriptional remodeling in leishmanial lesions. Weinkopff has published 40 papers, accumulating 679 citations and an h-index of 14. Her recent collaborations include work with Charity L. Washam, Manjunath Bettadapura, Steven Murdock, and Hayden Roys, all at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 14
- Publications: 40
- Citations: 687
Selected Publications
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Guanylate-binding proteins balance iNOS/Arg-1 in myeloid cells during <i>L. major</i> infection and promote host defense to infection (2026)
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Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267 (2025)
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Impaired lymphatic remodeling leads to immunopathology during non-healing cutaneous leishmaniasis 4376 (2025)
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From defense to disease: the multifaceted role of lymphatics during infection (2025)
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Guanylate-Binding Proteins Promote Host Defense Against <i>Leishmania major</i> by Balancing iNOS/Arg-1 in Myeloid Cells (2025)
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Dysregulated lymphatic remodeling promotes immunopathology during non-healing cutaneous leishmaniasis (2025)
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Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis (2025)
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HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection (2025)
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Platelets Modulate Leukocyte Population Composition Within Perivascular Adipose Tissue (2025)
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Host guanylate binding proteins participate in parasite control during Leishmania infection (2024)
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HIF-α signaling regulates the macrophage inflammatory response during <i>Leishmania major</i> infection (2024)
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Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs (2024)
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Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis (2024)
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Metabolically active neutrophils represent a permissive niche for Mycobacterium tuberculosis (2024)
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Investigating the platelet contribution to diet induced PVAT leukocyte infiltration (2024)
Research Interests
Leishmania, leishmaniasis, lymphatics, macrophages, vascular remodeling
Grants & Funding
As listed on this researcher's institutional profile.
- Partnerships for Biomedical Research in Arkansas - Admin Supplement NIH/Nat. Inst. of General Medical Sciences Principal Investigator
- Partnerships for Biomedical Research in Arkansas NIH Co-Investigator
- The Role of Myeloid Lineage Cells in Leishmaniasis NIH Principal Investigator
- Regulation of macrophage function during acute infection with Plasmodium NIH Co-Investigator
Collaboration Network
Top Collaborators
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- In vivo reprogramming of murine host immune response genes following Leishmania major infection
Showing 5 of 16 shared publications
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- In vivo reprogramming of murine host immune response genes following Leishmania major infection
Showing 5 of 16 shared publications
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
- Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis
- Distinct lymphatic remodeling is associated with healing and non-healing murine cutaneous leishmaniasis
Showing 5 of 14 shared publications
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- In vivo reprogramming of murine host immune response genes following Leishmania major infection
Showing 5 of 10 shared publications
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- In vivo reprogramming of murine host immune response genes following Leishmania major infection
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
- Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis
Showing 5 of 9 shared publications
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- In vivo reprogramming of murine host immune response genes following Leishmania major infection
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
- HIF-α signaling regulates the macrophage inflammatory response during <i>Leishmania major</i> infection
Showing 5 of 7 shared publications
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- In vivo reprogramming of murine host immune response genes following Leishmania major infection
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
Showing 5 of 7 shared publications
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis
- Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267
- Abstract 11421: The M2 Gene is a Determinant of Reovirus-Induced Myocarditis
- Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs
- From defense to disease: the multifaceted role of lymphatics during infection
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Platelets Modulate Leukocyte Population Composition Within Perivascular Adipose Tissue
- Investigating the platelet contribution to diet induced PVAT leukocyte infiltration
- Platelets Modulate Leukocyte Population Composition Within Perivascular Adipose Tissue
- Investigating the platelet contribution to diet induced PVAT leukocyte infiltration
- Platelets Modulate Leukocyte Population Composition Within Perivascular Adipose Tissue
- Investigating the platelet contribution to diet induced PVAT leukocyte infiltration
- Platelets Modulate Leukocyte Population Composition Within Perivascular Adipose Tissue
- Investigating the platelet contribution to diet induced PVAT leukocyte infiltration
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