Michelle E. Bishop

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Researcher

NCTR

Also affiliated: Center for Food Safety and Applied Nutrition (1995); United States Food and Drug Administration (1995–2024); Thomas Jefferson National Accelerator Facility (2003–2011); Wellcome Connecting Science (2024); Food and Drug Administration (2008)

Faculty Researcher

17 h-index 51 pubs 892 cited

Research Areas

Biomedical Subjects

OverviewAI-generated summary

Michelle E. Bishop's research focuses on toxicological studies, particularly investigating the genotoxicity and mutagenicity of various chemical compounds. Her work has involved extensive use of in vitro and in vivo models, including the Ames test and rodent studies, to assess the potential DNA damage and adverse health effects of substances like N-nitrosamines (NNK) and ortho-phthalaldehyde. Bishop has studied different exposure routes, such as nose-only inhalation, intraperitoneal injection, and oral gavage, to understand the toxicokinetics and genotoxic outcomes in male Sprague Dawley rats. Her research also explores the comparison of standard genotoxicity assays with organotypic cell cultures to better predict human health risks.

With an h-index of 17 and 51 total publications, Bishop has contributed to the field of toxicology. Her key collaborators include Robert H. Heflich, Matthew Bryant, Sherry M. Lewis, and Shu-Chieh Hu, all from the National Center for Toxicological Research, with whom she has co-authored multiple publications. Her work has been published in journals, with recent contributions in 2021 and upcoming work in 2024, 2025, and 2026, indicating continued activity in her research area.

Metrics

h-index: 17
Publications: 51
Citations: 892

Selected Publications

Adjusting the Preincubation Conditions to Enhance the Ames Test for Detecting the Mutagenicity of N ‐Nitrosamines (2026)

Environmental and Molecular Mutagenesis DOI OpenAlex
Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays (2026)

Archives of Toxicology 1 citation DOI OpenAlex
HESI GTTC ring trial: Concordance between Ames and rodent carcinogenicity outcomes for N-nitrosamines (NAs) with rat and hamster metabolic conditions (2025)

Regulatory Toxicology and Pharmacology 14 citations DOI OpenAlex
Optimizing the detection of N-nitrosamine mutagenicity in the Ames test (2024)

Regulatory Toxicology and Pharmacology 31 citations DOI OpenAlex
90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021)

Food and Chemical Toxicology 6 citations DOI OpenAlex
14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021)

Toxicological Sciences 7 citations DOI OpenAlex
Toxicokinetic and Genotoxicity Study of NNK in Male Sprague Dawley Rats Following Nose-Only Inhalation Exposure, Intraperitoneal Injection, and Oral Gavage (2021)

Toxicological Sciences 15 citations DOI OpenAlex
A Streamlined and High-Throughput Error-Corrected Next-Generation Sequencing Method for Low Variant Allele Frequency Quantitation (2019)

Toxicological Sciences 5 citations DOI OpenAlex
Lifespan Kras mutation levels in lung and liver of B6C3F1 mice (2018)

Environmental and Molecular Mutagenesis 2 citations DOI OpenAlex
In Vivo Alkaline Comet Assay and Enzyme-modified Alkaline Comet Assay for Measuring DNA Strand Breaks and Oxidative DNA Damage in Rat Liver (2016)

Journal of Visualized Experiments 2 citations DOI OpenAlex
In Vivo Alkaline Comet Assay and Enzyme-modified Alkaline Comet Assay for Measuring DNA Strand Breaks and Oxidative DNA Damage in Rat Liver (2016)

Journal of Visualized Experiments 17 citations DOI OpenAlex
In vivo genotoxicity of estragole in male<scp>F</scp>344 rats (2014)

Environmental and Molecular Mutagenesis 17 citations DOI OpenAlex
Sex-specific dose-response analysis of genotoxicity in cyproterone acetate-treated F344 rats (2014)

Mutation Research/Genetic Toxicology and Environmental Mutagenesis 9 citations DOI OpenAlex
Assessment by Ames test and comet assay of toxicity potential of polymer used to develop field-capable rapid-detection device to analyze environmental samples (2014)

Applied Nanoscience 18 citations DOI OpenAlex
Genotoxicity of doxorubicin in F344 rats by combining the comet assay, flow‐cytometric peripheral blood micronucleus test, and pathway‐focused gene expression profiling (2013)

Environmental and Molecular Mutagenesis 26 citations DOI OpenAlex