Match tier Listed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-16

Henrique Rodrigues

Researcher

Faculty Researcher

5 h-index 26 pubs 254 cited

  • Humans
  • Female
  • DNA-Binding Proteins
  • Pancreatic Neoplasms
  • Radiation Tolerance
  • Thyroid Neoplasms
  • Signal Transduction
  • Gene Expression Regulation, Neoplastic
  • Proto-Oncogene Proteins p21(ras)
  • MicroRNAs
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Aged
  • Male
  • Animals

Biography and Research Information

OverviewAI-generated summary

Henrique Rodrigues' research focuses on understanding the molecular mechanisms that contribute to cancer radioresistance, particularly in pancreatic and thyroid malignancies. His work has identified signaling pathways, such as the RAS-RAF-miR-296-3p axis, that can increase the expression of Rad18, thereby augmenting resistance to radiation therapy. Rodrigues has also investigated the role of SETD2 in rectal cancer, finding that its loss predicts response to chemoradiotherapy and validating these findings in preclinical models. Further research includes exploring methods to enhance rectal cancer radiosensitivity and protect the gut through dietary interventions like methionine restriction.

Rodrigues is affiliated with the University of Arkansas for Medical Sciences and collaborates with researchers including Oscar Zuniga and Lokesh Akana. His published work spans 2024-2025, with a recent focus on cancer biology and treatment. His scholarship metrics include an h-index of 5, with 26 total publications and 254 total citations.

Metrics

  • h-index: 5
  • Publications: 26
  • Citations: 254

Selected Publications

  • Abstract A033: Targeting SETD2 in Combination with Radiotherapy in Rectal Cancer (2025)
    Molecular Cancer Therapeutics DOI OpenAlex
  • SETD2 Loss Predicts Response to Chemoradiotherapy in Rectal Cancer: Clinical Outcomes and Preclinical Validation in Orthotopic Models (2025)
    International Journal of Radiation Oncology*Biology*Physics DOI OpenAlex
  • Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction (2025)
    Research Square DOI OpenAlex
  • Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1 (2024)
    Cancer Research DOI OpenAlex
  • RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers (2024)
    Cancer Letters 7 citations DOI OpenAlex
  • Abstract A006: Targeting SETD2 in combination with radiotherapy in rectal cancer (2024)
    Cancer Research DOI OpenAlex
  • Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy (2023)
    International Journal of Radiation Oncology*Biology*Physics DOI OpenAlex
  • Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer (2023)
    Cancer Research DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

21 Collaborators 4 Institutions 1 Country

Top Collaborators

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