Biography and Research Information
OverviewAI-generated summary
Sydnye Shuttlewoth's research focuses on characterizing mechanisms that can improve cancer immunotherapies. Her work investigates strategies to enhance CAR-T cell function and overcome resistance to combination therapies. Specifically, she has studied the activation of ATF6 as a means to improve efficacy in immune checkpoint blockade (ICB). Additionally, her research explores the generation of EZH2-inhibitor resistant CAR-T cells to sustain their function in combination treatment regimens.
Metrics
- Publications: 2
Selected Publications
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Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy (2026)
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Abstract 5189: Generating EZH2-inhibitor resistant CAR-T cells to sustain function for combination therapy (2026)
Collaboration Network
Top Collaborators
- Abstract 5189: Generating EZH2-inhibitor resistant CAR-T cells to sustain function for combination therapy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 5189: Generating EZH2-inhibitor resistant CAR-T cells to sustain function for combination therapy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 5189: Generating EZH2-inhibitor resistant CAR-T cells to sustain function for combination therapy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 5189: Generating EZH2-inhibitor resistant CAR-T cells to sustain function for combination therapy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 5189: Generating EZH2-inhibitor resistant CAR-T cells to sustain function for combination therapy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 5189: Generating EZH2-inhibitor resistant CAR-T cells to sustain function for combination therapy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
- Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy
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