Antiño R. Allen

◆ ARA Academy Federal Grant PI High Impact

Professor

UAMS

Last publication 2026 Last refreshed 2026-05-22

faculty

arallen@uams.edu

26 h-index 87 pubs 1,966 cited

Research Areas

Links

ORCID Lab Website UAMS TRI Profile

OverviewAI-generated summary

Antiño R. Allen's research focuses on understanding the biological consequences of environmental stressors, particularly space radiation and chemotherapy, on the central nervous system and other organ systems. His work investigates mechanisms of neuroprotection and potential therapeutic interventions. Allen has studied the effects of space radiation on cognitive function and neuronal structures, such as dendritic spines, using mouse models. His research also examines chemotherapy-induced side effects, including cognitive impairment, inflammation, and oxidative stress, in various tissues like the gut, liver, and ovaries.

Several of Allen's publications explore the potential of natural compounds and synthetic molecules as neuroprotective agents. This includes research on sulforaphane, piperlongumine, and MnSOD mimetics for their roles in combating oxidative stress and their anticancer actions. He has received federal funding from the NIH/National Cancer Institute to investigate MnBuOE as a chemosensitizer and neuroprotector for breast cancer. Allen also contributes to broader research and training initiatives, serving as Co-PI on an NIH-funded Initiative for Maximizing Student Development (IMSD) grant.

With a career marked by over 85 publications and 1,923 citations, Allen holds an h-index of 25. He is recognized as a high-impact researcher and an ARA Academy member. His collaborations extend to researchers at the University of Arkansas for Medical Sciences and the University of Arkansas for Fayetteville, contributing to a network focused on health sciences and radiation health.

Metrics

h-index: 26
Publications: 87
Citations: 1,966

Selected Publications

Changes in gut, microbiome, and cognition after doxorubicin, cyclophosphamide, and paclitaxel chemotherapy treatment (2026)

DOI OpenAlex
Implications of cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy on hippocampal-dependent cognition and gut microbiome (2025)

1 citation DOI OpenAlex
Manganese Superoxide Dismutase: Structure, Function, and Implications in Human Disease (2025)

16 citations DOI OpenAlex
The adverse effects of chemotherapy on bone mass are not prevented by senolytics (2025)

DOI OpenAlex
A Bibliometric Analysis of Research Examining How Space Radiation Affects Human and Rodent Cognition, 1990–2023 (2024)

DOI OpenAlex
MnSOD Mimetics in Therapy: Exploring Their Role in Combating Oxidative Stress-Related Diseases (2024)

18 citations DOI OpenAlex
Summer undergraduate biomedical research program for underrepresented minority students in a rural, low-income state (2024)

1 citation DOI OpenAlex
Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior (2023)

13 citations DOI OpenAlex
Sulforaphane’s Multifaceted Potential: From Neuroprotection to Anticancer Action (2023)

49 citations DOI OpenAlex
Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart (2023)

8 citations DOI OpenAlex
Abstract P3-08-08: Establishment of a Breast Cancer Rat Model of Chemotherapy-Induced Cardiotoxicity (2023)

DOI OpenAlex
Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model (2023)

9 citations DOI OpenAlex
Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, And Cognition in an Aged Murine Model (2022)

DOI OpenAlex
Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model (2022)

DOI OpenAlex
Chemotherapy induced oxidative stress in the ovary: drug-dependent mechanisms and potential interventions (2022)

19 citations DOI OpenAlex

View all publications on OpenAlex →

ARA Academy 2023 ARA Fellow

Dr. Allen is an Associate Professor and Graduate Program Director at the Division of Radiation Health, Department of Pharmaceutical Sciences at UAMS. He holds a PhD in Evolution, Ecology, and Behavior and served as a Captain in the US Army Infantry from 2004-2010. His work focuses on community science development and introducing research and discovery to underserved populations in Arkansas.

Policy Impact

Builds research capacity and STEM engagement in underserved Arkansas communities, expanding the state's scientific workforce pipeline and health research infrastructure.