Charles M. Skinner

Researcher

Last publication 2025 Last refreshed 2026-05-23

faculty

14 h-index 46 pubs 908 cited

Biography and Research Information

OverviewAI-generated summary

Charles M. Skinner's research investigates the toxicological and pharmacological effects of cannabis-derived compounds, particularly cannabidiol (CBD), utilizing both animal models and human-relevant in vitro systems. His work has explored inter-strain variability in mouse responses to CBD-rich cannabis extracts and employed a human quad liver-on-chip system to bridge the gap between animal and human studies in toxicology and pharmacology. Skinner has also examined the effects of space-relevant radiation, specifically proton and oxygen ion irradiation, on cardiovascular function in rabbits and the intestinal one-carbon metabolism pathway and microbiome in mice. His research extends to assessing cytogenetic and epigenetic aberrations in peripheral lymphocytes, as demonstrated in studies of the Marshallese population in northwest Arkansas.

Skinner's scholarly output includes 46 publications with approximately 900 citations, and he holds an h-index of 14. He has established a network of collaborators at the University of Arkansas for Medical Sciences, including Igor Koturbash, Laura Ewing, Reid D. Landes, and Martin Hauer-Jensen, with whom he has co-authored multiple publications. His recent work spans from 2022 to 2025, indicating continued activity in his research areas.

Metrics

  • h-index: 14
  • Publications: 46
  • Citations: 908

Selected Publications

  • Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice (2025)
  • Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract (2024)
    3 citations DOI OpenAlex
  • Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice (2024)
    1 citation DOI OpenAlex
  • Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model (2023)
    5 citations DOI OpenAlex
  • Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese (2022)
    9 citations DOI OpenAlex

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Collaboration Network

38 Collaborators 15 Institutions 1 Country

Top Collaborators

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