Match tier
Listed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
C
Charles M. Skinner
Senior Research Associate
Also affiliated: The University of Texas at San Antonio Health Science Center (2008–2009); Arkansas Children's Nutrition Center (2006); Arkansas Children's Research Institute (2024)
14 h-index
33 pubs
847 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Charles M. Skinner's research investigates the toxicological and pharmacological effects of cannabis-derived compounds, particularly cannabidiol (CBD), utilizing both animal models and human-relevant in vitro systems. His work has explored inter-strain variability in mouse responses to CBD-rich cannabis extracts and employed a human quad liver-on-chip system to bridge the gap between animal and human studies in toxicology and pharmacology. Skinner has also examined the effects of space-relevant radiation, specifically proton and oxygen ion irradiation, on cardiovascular function in rabbits and the intestinal one-carbon metabolism pathway and microbiome in mice. His research extends to assessing cytogenetic and epigenetic aberrations in peripheral lymphocytes, as demonstrated in studies of the Marshallese population in northwest Arkansas.
Skinner's scholarly output includes 46 publications with approximately 900 citations, and he holds an h-index of 14. He has established a network of collaborators at the University of Arkansas for Medical Sciences, including Igor Koturbash, Laura Ewing, Reid D. Landes, and Martin Hauer-Jensen, with whom he has co-authored multiple publications. His recent work spans from 2022 to 2025, indicating continued activity in his research areas.
Metrics
- h-index: 14
- Publications: 33
- Citations: 847
Positions
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Senior Research Associate publications 2006–2025University of Arkansas for Medical Sciences Institution web page
Selected Publications
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Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice (2025)
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Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract (2024)
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Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice (2024)
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Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model (2023)
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Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese (2022)
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Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration (2020)
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Dietary Methionine Supplementation Exacerbates Gastrointestinal Toxicity in a Mouse Model of Abdominal Irradiation (2020)
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Green Tea Extract as a Safe and Effective Dietary Supplement: Lessons Learned from Mice (2020)
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Cannabidiol: From Drug Interaction Potential to Modulation of the Gut Microbiome (2020)
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Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract (2020)
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Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome (2020)
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Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration (2019)
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Reply to Flugge: the anti-metastatic potential of methionine restriction in melanoma (2019)
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Changes in one-carbon metabolism and DNA methylation in the hearts of mice exposed to space environment-relevant doses of oxygen ions (16O) (2019)
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Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model (2019)
Collaboration Network
Top Collaborators
Igor Koturbash
University of Arkansas for Medical Sciences
21 shared publications
In database
- Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
- Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology
- Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart
- Densely ionizing radiation affects DNA methylation of selective LINE-1 elements
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
Showing 5 of 21 shared publications
Laura Ewing
University of Arkansas for Medical Sciences
16 shared publications
In database
- Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome
- Safety assessment of the dietary supplement OxyELITE™ Pro (New Formula) in inbred and outbred mouse strains
Showing 5 of 16 shared publications
Isabelle R. Miousse
University of Arkansas for Medical Sciences
13 shared publications
In database
- Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology
- Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart
- Densely ionizing radiation affects DNA methylation of selective LINE-1 elements
- Modulation of dietary methionine intake elicits potent, yet distinct, anticancer effects on primary versus metastatic tumors
- Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome
Showing 5 of 13 shared publications
Bill J. Gurley
Office of Dietary Supplements
11 shared publications
In database
- Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Safety assessment of the dietary supplement OxyELITE™ Pro (New Formula) in inbred and outbred mouse strains
- Decaffeinated Green Tea Extract Does Not Elicit Hepatotoxic Effects and Modulates the Gut Microbiome in Lean B6C3F1 Mice
Showing 5 of 11 shared publications
Martin Hauer‐Jensen
University of Arkansas for Medical Sciences
9 shared publications
In database
- Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology
- Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart
- Densely ionizing radiation affects DNA methylation of selective LINE-1 elements
- Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome
- Changes in one-carbon metabolism and DNA methylation in the hearts of mice exposed to space environment-relevant doses of oxygen ions (16O)
Showing 5 of 9 shared publications
Mahmoud A. ElSohly
University of Mississippi (US)
9 shared publications
- Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Safety assessment of the dietary supplement OxyELITE™ Pro (New Formula) in inbred and outbred mouse strains
- Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration
Showing 5 of 9 shared publications
Charles M. Quick
University of Arkansas for Medical Sciences
9 shared publications
In database
- Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Modulation of dietary methionine intake elicits potent, yet distinct, anticancer effects on primary versus metastatic tumors
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration
Showing 5 of 9 shared publications
Marjan Boerma
University of Arkansas for Medical Sciences
8 shared publications
In database
- Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart
- Changes in one-carbon metabolism and DNA methylation in the hearts of mice exposed to space environment-relevant doses of oxygen ions (16O)
- Dietary Methionine Supplementation Exacerbates Gastrointestinal Toxicity in a Mouse Model of Abdominal Irradiation
- Impact of obesity on the toxicity of a multi-ingredient dietary supplement, OxyELITE Pro™ (New Formula), using the novel NZO/HILtJ obese mouse model: Physiological and mechanistic assessments
- Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese
Showing 5 of 8 shared publications
Rupak Pathak
University of Arkansas for Medical Sciences
7 shared publications
In database
- Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology
- Densely ionizing radiation affects DNA methylation of selective LINE-1 elements
- Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome
- Dietary Methionine Supplementation Exacerbates Gastrointestinal Toxicity in a Mouse Model of Abdominal Irradiation
- Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese
Showing 5 of 7 shared publications
Kristy Kutanzi
University of Arkansas for Medical Sciences
7 shared publications
In database
- Densely ionizing radiation affects DNA methylation of selective LINE-1 elements
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Modulation of dietary methionine intake elicits potent, yet distinct, anticancer effects on primary versus metastatic tumors
- Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome
- Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration
Showing 5 of 7 shared publications
Larry Walker
University of Mississippi (US)
7 shared publications
- Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
Showing 5 of 7 shared publications
Stefanie Kennon‐McGill
University of Arkansas for Medical Sciences
6 shared publications
In database
- Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Decaffeinated Green Tea Extract Does Not Elicit Hepatotoxic Effects and Modulates the Gut Microbiome in Lean B6C3F1 Mice
- Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
Showing 5 of 6 shared publications
Mitchell R. McGill
Office of Dietary Supplements
6 shared publications
In database
- Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Decaffeinated Green Tea Extract Does Not Elicit Hepatotoxic Effects and Modulates the Gut Microbiome in Lean B6C3F1 Mice
- Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
Showing 5 of 6 shared publications
Eric U. Yee
University of Arkansas for Medical Sciences
6 shared publications
In database
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Dietary Methionine Supplementation Exacerbates Gastrointestinal Toxicity in a Mouse Model of Abdominal Irradiation
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
Showing 5 of 6 shared publications
Vijayalakshmi Sridharan
University of Arkansas for Medical Sciences
5 shared publications
In database
- Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart
- Changes in one-carbon metabolism and DNA methylation in the hearts of mice exposed to space environment-relevant doses of oxygen ions (16O)
- Impact of obesity on the toxicity of a multi-ingredient dietary supplement, OxyELITE Pro™ (New Formula), using the novel NZO/HILtJ obese mouse model: Physiological and mechanistic assessments
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
- Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice
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