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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
S
Stephanie D. Byrum
High Impact
Researcher
Also affiliated: Arkansas Children's Hospital (2018–2026); St. Jude Children's Research Hospital (2025–2026); The University of Texas MD Anderson Cancer Center (2024); Johns Hopkins University (2013); University of California, Los Angeles (2022); University of Arkansas Medical Center (2018); Skive Hospital (2024); Quantitative BioSciences (2025); Advanced Projects Research Incorporated (United States) (2019); Cancer Research Center (2024); Winthrop Rockefeller Foundation (2021–2024); Arkansas Children's Nutrition Center (2018–2024); Arkansas Department of Agriculture (2013–2018); Banner MD Anderson Cancer Center (2024); Penn State Milton S. Hershey Medical Center (2013)
Faculty Researcher
33 h-index
301 pubs
4,566 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Stephanie D. Byrum is a faculty member at the University of Arkansas for Medical Sciences whose research focuses on understanding molecular mechanisms in disease. Her work investigates the role of protein interactions and epigenetic modifications in cellular processes, particularly as they relate to cancer development and immune responses. Byrum has published on topics including phase separation in chromatin, the function of specific kinases in transcription, and the development of targeted therapies like PROTAC degraders for cancer treatment. Her research group also explores the involvement of proteins such as TNRC18 in silencing endogenous retrotransposons and PCSK9 in vascular aging.
Her scholarship metrics include an h-index of 33, with 291 total publications and 4,466 citations. Byrum is recognized as a highly cited researcher. She frequently collaborates with colleagues at the University of Arkansas for Medical Sciences, including Samuel G. Mackintosh, Alan J. Tackett, Charity L. Washam, and Aaron J. Storey, with whom she has co-authored multiple publications. Her laboratory website details ongoing research and maintains a list of publications.
Metrics
- h-index: 33
- Publications: 301
- Citations: 4,566
Selected Publications
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Gonadotrope remodeling in sustained low estrogen states: single-cell transcriptomic analysis reveals gonadotrope subtypes and activation of stem cell populations (2026)
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Guanylate-binding proteins balance iNOS/Arg-1 in myeloid cells during <i>L. major</i> infection and promote host defense to infection (2026)
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Dynamic global acetylation remodeling during the yeast heat shock response (2026)
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Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells (2025)
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SAT-001 Impact of VCD-induced Menopause on Gonadotrope Transcriptomics Reveals Estrogen-dependent Genes in the GnRH Signaling Pathway (2025)
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Multicellular tumor-stromal interactions recapitulate aspects of therapeutic response and human oncogenic signaling in a 3D disease model for H3K27M-altered DIPG (2025)
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High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes (2025)
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BAHCC1 binds H4K20me1 to facilitate the MCM complex loading and DNA replication (2025)
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Guanylate-Binding Proteins Promote Host Defense Against <i>Leishmania major</i> by Balancing iNOS/Arg-1 in Myeloid Cells (2025)
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Protective effects of factor XI inhibition by abelacimab in a baboon model of live Staphylococcus aureus sepsis (2025)
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Rare SNP in the <i>HELB</i> gene interferes with RPA interaction and cellular function of HELB (2025)
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<i>BRCA1</i> influences whole body metabolism in humanized mice (2025)
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Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis (2025)
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HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection (2025)
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Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice (2025)
Collaboration Network
Top Collaborators
Samuel G. Mackintosh
University of Arkansas for Medical Sciences
22 shared publications
In database
- Phase separation drives aberrant chromatin looping and cancer development
- CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
Showing 5 of 22 shared publications
Alan J. Tackett
University of Arkansas for Medical Sciences
16 shared publications
In database
- Phase separation drives aberrant chromatin looping and cancer development
- Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
Showing 5 of 16 shared publications
Aaron J. Storey
University of Arkansas for Medical Sciences
11 shared publications
In database
- Phase separation drives aberrant chromatin looping and cancer development
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
Showing 5 of 11 shared publications
Charity L. Washam
University of Arkansas for Medical Sciences
11 shared publications
In database
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer
- Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells
- PHF19 inhibition as a therapeutic target in multiple myeloma
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
Showing 5 of 11 shared publications
Jordan T. Bird
University of Arkansas for Medical Sciences
9 shared publications
In database
- Differences in cell death in methionine versus cysteine depletion
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer
- Deficiency of N-glycanase 1 perturbs neurogenesis and cerebral development modeled by human organoids
- Characterization of methionine dependence in melanoma cells
Showing 5 of 9 shared publications
Ling Cai
8 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
Showing 5 of 8 shared publications
Gang Greg Wang
8 shared publications
- Phase separation drives aberrant chromatin looping and cancer development
- A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
Showing 5 of 8 shared publications
Allen Gies
University of Arkansas for Medical Sciences
8 shared publications
In database
- Circulating Exosomal microRNAs as Predictive Biomarkers of Neoadjuvant Chemotherapy Response in Breast Cancer
- Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer
- Characterization of methionine dependence in melanoma cells
- Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells
- Targeting mitochondria in the aged cerebral vasculature with SS-31, a proteomic study of brain microvessels
Showing 5 of 8 shared publications
Alex Lagasse
University of Arkansas for Medical Sciences
7 shared publications
In database
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice
- High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes
Showing 5 of 7 shared publications
Tiffany K. Miles
Arkansas Children's Hospital
7 shared publications
In database
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice
- High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes
Showing 5 of 7 shared publications
Melanie C MacNicol
University of Arkansas for Medical Sciences
7 shared publications
In database
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice
- High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes
Showing 5 of 7 shared publications
Gwen V. Childs
University of Arkansas for Medical Sciences
7 shared publications
In database
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice
- High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes
Showing 5 of 7 shared publications
Angus M. MacNicol
University of Arkansas for Medical Sciences
7 shared publications
In database
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice
- High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes
Showing 5 of 7 shared publications
Angela K. Odle
University of Arkansas for Medical Sciences
7 shared publications
In database
- Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Ablation of Leptin Receptor Signaling Alters Somatotrope Transcriptome Maturation in Female Mice
- 8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice
- High fat diet-induced loss of pituitary plasticity in aging female mice with ablated leptin signaling in somatotropes
Showing 5 of 7 shared publications
Ricky D. Edmondson
University of Arkansas for Medical Sciences
6 shared publications
In database
- Phase separation drives aberrant chromatin looping and cancer development
- TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
- Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
- ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism
- A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing
Showing 5 of 6 shared publications
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