Frederick A. Beland
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Research Chemist
Also affiliated: Courtauld Institute of Art (1984); Roswell Park Comprehensive Cancer Center (2008); National Institutes of Health (1994–2005); Environmental Protection Agency (1981); University of Minnesota (2002); Fisheries and Oceans Canada (2000); United States Food and Drug Administration (1981–2026); Electric Power Research Institute (1998); University of Lisbon (1994); University of Rhode Island (2003); Soochow University (1978); Wilmington University (2000); Montana State University (1973–1977); Biochemical Society (2012–2025); University Medical Center (2002); Jefferson Community and Technical College (2010); In-Q-Tel (2012–2015); Soochow University (1978); University of Chicago (1976–1978); Perspectives Charter School (1994); May Institute (1976–1978); Orszagos Kornyezetegeszsegugyi Intezet (1998–2005); Rede de Química e Tecnologia (2008); National Cancer Institute (1994–2008); Food and Drug Administration (1985–2012); National Center for Epidemiology (2005); Centre international de recherche sur le cancer (2023); Instituto Superior Técnico (2008–2012); The Ohio State University (1986); New York University (2002); University of Montana (1991); Universidade Nova de Lisboa (2008–2010); University of California, Berkeley (1980–2018)
Faculty Researcher
Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Frederick A. Beland is a research chemist whose work investigates the toxicological effects of various substances on biological systems. His research has explored the carcinogenicity of compounds such as aspartame, methyleugenol, and isoeugenol, as well as the in vitro effects of cannabidiol and its metabolites on mammalian cells. Beland has also studied the toxicity of polyethylene glycols in Sprague Dawley rats and the impact of inorganic arsenic on neuronal development in zebrafish.
His research also extends to cellular and molecular mechanisms of toxicity, including alterations in DNA methylation and gene expression in the context of diet-induced obesity, and the covalent modification of histones by drug derivatives. Beland has contributed to the evaluation of alternative skin barrier models for dermal absorption studies. He leads a research group and maintains an active laboratory website, and his work has resulted in a significant number of publications and citations, designating him as a highly cited researcher.
Metrics
- h-index: 71
- Publications: 499
- Citations: 19,156
Selected Publications
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Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays (2026)
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Physiologically based pharmacokinetic modeling of oseltamivir in pregnant rhesus macaques to inform clinical dosing across trimesters (2025)
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Pharmacokinetics of cannabidiol and its metabolites in rhesus monkeys and New Zealand White rabbits (2025)
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NAD(P)+-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite (2025)
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Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice (2025)
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Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development (2025)
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Flow cytometric analysis of the SARS coronavirus 2 antibodies in human plasma (2025)
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A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice (2024)
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Cellular and molecular alterations in a human hepatocellular in vitro model of nonalcoholic fatty liver disease development and stratification (2023)
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Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound (2023)
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Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice (2023)
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Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish (2023)
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Polycyclic Aromatic Hydrocarbons, Methylated Polycyclic Aromatic Hydrocarbons, and Polycyclic Azaaromatic Compounds (2023)
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Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro (2023)
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Abstract 6017: Exposure-related DNA methylation and gene expression changes in mammary glands of Sprague Dawley rats treated with lorcaserin (2023)
Collaboration Network
Top Collaborators
- Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet
- Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
- Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound
- Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice
Showing 5 of 9 shared publications
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice
- Toxicological evaluation of brominated vegetable oil in Sprague Dawley rats
- A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice
- Effect of urinary pH upon the renal toxicity of melamine and cyanuric acid
Showing 5 of 7 shared publications
- Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet
- Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice
- Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice
- A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice
- Cellular and molecular alterations in a human hepatocellular in vitro model of nonalcoholic fatty liver disease development and stratification
Showing 5 of 7 shared publications
- Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet
- Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice
- Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice
- A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice
- Cellular and molecular alterations in a human hepatocellular in vitro model of nonalcoholic fatty liver disease development and stratification
Showing 5 of 7 shared publications
- Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet
- Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice
- Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice
- A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice
- Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice
- Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet
- Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice
- Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice
- A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice
- Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice
- NAD(P)+-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite
- Flow cytometric analysis of the SARS coronavirus 2 antibodies in human plasma
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound
- Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice
- Pharmacokinetics of cannabidiol and its metabolites in rhesus monkeys and New Zealand White rabbits
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro
- Toxicological evaluation of brominated vegetable oil in Sprague Dawley rats
- Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice
- Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice
- Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice
- A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice
- NAD(P)+-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite
- In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells
- Toxicological evaluation of brominated vegetable oil in Sprague Dawley rats
- Effect of urinary pH upon the renal toxicity of melamine and cyanuric acid
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Effect of urinary pH upon the renal toxicity of melamine and cyanuric acid
- Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice
- In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells
- NAD(P)+-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite
- Pharmacokinetics of cannabidiol and its metabolites in rhesus monkeys and New Zealand White rabbits
- Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro
- Polycyclic Aromatic Hydrocarbons, Methylated Polycyclic Aromatic Hydrocarbons, and Polycyclic Azaaromatic Compounds
- Pharmacokinetics of cannabidiol and its metabolites in rhesus monkeys and New Zealand White rabbits
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish
- Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays
- Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development
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