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Biography and Research Information
OverviewAI-generated summary
Henrique Rodrigues' research focuses on understanding the molecular mechanisms that contribute to cancer radioresistance, particularly in pancreatic and thyroid malignancies. His work has identified signaling pathways, such as the RAS-RAF-miR-296-3p axis, that can increase the expression of Rad18, thereby augmenting resistance to radiation therapy. Rodrigues has also investigated the role of SETD2 in rectal cancer, finding that its loss predicts response to chemoradiotherapy and validating these findings in preclinical models. Further research includes exploring methods to enhance rectal cancer radiosensitivity and protect the gut through dietary interventions like methionine restriction.
Rodrigues is affiliated with the University of Arkansas for Medical Sciences and collaborates with researchers including Oscar Zuniga and Lokesh Akana. His published work spans 2024-2025, with a recent focus on cancer biology and treatment. His scholarship metrics include an h-index of 5, with 26 total publications and 254 total citations.
Metrics
- h-index: 5
- Publications: 26
- Citations: 254
Selected Publications
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Abstract A033: Targeting SETD2 in Combination with Radiotherapy in Rectal Cancer (2025)
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SETD2 Loss Predicts Response to Chemoradiotherapy in Rectal Cancer: Clinical Outcomes and Preclinical Validation in Orthotopic Models (2025)
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Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction (2025)
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Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1 (2024)
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RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers (2024)
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Abstract A006: Targeting SETD2 in combination with radiotherapy in rectal cancer (2024)
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Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy (2023)
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Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer (2023)
Collaboration Network
Top Collaborators
- RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers
- Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer
- Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy
- Abstract A006: Targeting SETD2 in combination with radiotherapy in rectal cancer
- Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1
Showing 5 of 8 shared publications
- Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy
- Abstract A006: Targeting SETD2 in combination with radiotherapy in rectal cancer
- Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
- SETD2 Loss Predicts Response to Chemoradiotherapy in Rectal Cancer: Clinical Outcomes and Preclinical Validation in Orthotopic Models
Showing 5 of 6 shared publications
- RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers
- Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer
- Abstract A006: Targeting SETD2 in combination with radiotherapy in rectal cancer
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
- Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
- Abstract A033: Targeting SETD2 in Combination with Radiotherapy in Rectal Cancer
- Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
- Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer
- Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1
- Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
- Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
- Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer
- Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy
- Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy
- RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers
- RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers
- RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers
- RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers
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