Biography and Research Information
OverviewAI-generated summary
James A. Hendrixson's research investigates the molecular mechanisms of bone metabolism and strength, with a particular focus on the role of autophagy and its regulators. His work has explored the impact of manipulating the master autophagy regulator Tfeb in osteoblast lineage cells, demonstrating that its activation can increase bone mass and strength. Hendrixson has also examined the consequences of losing chaperone-mediated autophagy, finding no alteration in age-related bone loss in male mice.
His publications also include studies on gene editing technologies, comparing CRISPR interference and the Cre-loxP system for cell type-specificity. Hendrixson collaborates with researchers at the University of Arkansas for Medical Sciences, including Melda Onal and Julie Crawford, with whom he has multiple shared publications. His scholarly output is characterized by an h-index of 3 and 16 citations across 4 publications.
Metrics
- h-index: 3
- Publications: 4
- Citations: 16
Selected Publications
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Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength (2025)
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CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength (2024)
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Loss of chaperone‐mediated autophagy does not alter age‐related bone loss in male mice (2024)
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CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system (2023)
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Retroaortic Left Renal Vein: An Incidental Finding During Cadaver Dissection (2022)
Collaboration Network
Top Collaborators
Julie Crawford
Institute for Musculoskeletal Health
4 shared publications
In database
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- Loss of chaperone‐mediated autophagy does not alter age‐related bone loss in male mice
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Melda Onal
University of Arkansas for Medical Sciences
4 shared publications
In database
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- Loss of chaperone‐mediated autophagy does not alter age‐related bone loss in male mice
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
A. Gordon James
University of Arkansas for Medical Sciences
3 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- Loss of chaperone‐mediated autophagy does not alter age‐related bone loss in male mice
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Dominique J. Laster
University of Arkansas for Medical Sciences
2 shared publications
In database
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- Loss of chaperone‐mediated autophagy does not alter age‐related bone loss in male mice
Nisreen Akel
University of Arkansas for Medical Sciences
2 shared publications
In database
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- Loss of chaperone‐mediated autophagy does not alter age‐related bone loss in male mice
Stuart B. Berryhill
University of Arkansas for Medical Sciences
2 shared publications
In database
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- Loss of chaperone‐mediated autophagy does not alter age‐related bone loss in male mice
Intawat Nookaew
University of Arkansas for Medical Sciences
2 shared publications
In database
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
Ilham Kadhim
University of Arkansas for Medical Sciences
2 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Jacob Laster
University of Arkansas for Medical Sciences
2 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Jeff Thostenson
University of Arkansas for Medical Sciences (US)
2 shared publications
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Amy Y. Sato
University of Arkansas for Medical Sciences
2 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Maria Almeida
Institute for Musculoskeletal Health
2 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Alicen James
University of Arkansas for Medical Sciences (US)
1 shared publication
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
Qiang Fu
University of Arkansas for Medical Sciences (US)
1 shared publication
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
Jeff D. Thostenson
University of Arkansas for Medical Sciences
1 shared publication
In database
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
Similar Researchers
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