I
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Ilham Kadhim's research focuses on the molecular mechanisms underlying bone biology, particularly in relation to aging and autophagy. Recent publications investigate the role of the master autophagy regulator Tfeb in osteoblast lineage cells, demonstrating that its elevation can increase bone mass and strength. Kadhim has also explored whether mitochondrial oxidative stress or decreased autophagy in these cells can replicate the detrimental effects of aging on bone mechanoresponsiveness. Collaborations include work with Melda Onal, A. Gordon James, and Maria Almeida at the University of Arkansas for Medical Sciences, with whom Kadhim has co-authored multiple publications. The researcher's work has also touched upon cellular delivery methods for compounds and programmed cell death in cancer cells, as well as pathways related to aging and vacuole trafficking.
Metrics
- h-index: 3
- Publications: 6
- Citations: 15
Selected Publications
-
Renal Hemodynamics Underlie Hepatorenal Physiology in Bile Duct-Ligated Rats (2026)
-
Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength (2025)
-
Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness (2025)
-
CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength (2024)
-
Encapsulation of Inositol Hexakisphosphate with Chitosan via Gelation to Facilitate Cellular Delivery and Programmed Cell Death in Human Breast Cancer Cells (2024)
-
Up-regulation of Osh6 boosts an anti-aging membrane trafficking pathway toward vacuoles (2022)
Collaboration Network
Top Collaborators
A. Gordon James
University of Arkansas for Medical Sciences
3 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Maria Almeida
University of Arkansas Medical Center
3 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Melda Onal
Institute for Musculoskeletal Health
3 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
James A. Hendrixson
University of Arkansas for Medical Sciences
2 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Jacob Laster
University of Arkansas for Medical Sciences
2 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Julie Crawford
Institute for Musculoskeletal Health
2 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Jeff Thostenson
University of Arkansas for Medical Sciences (US)
2 shared publications
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Amy Y. Sato
University of Arkansas for Medical Sciences
2 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Jinhu Xiong
University of Arkansas Medical Center
2 shared publications
In database
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness
Nazneen Begum
University of Arkansas at Little Rock (US)
1 shared publication
- Up-regulation of Osh6 boosts an anti-aging membrane trafficking pathway toward vacuoles
William P. King
University of Arkansas at Little Rock (US)
1 shared publication
- Up-regulation of Osh6 boosts an anti-aging membrane trafficking pathway toward vacuoles
Licheng Xu
University of Arkansas at Little Rock (US)
1 shared publication
- Up-regulation of Osh6 boosts an anti-aging membrane trafficking pathway toward vacuoles
Fusheng Tang
University of Arkansas at Little Rock (US)
1 shared publication
- Up-regulation of Osh6 boosts an anti-aging membrane trafficking pathway toward vacuoles
Adeolu Sunday Oluremi
University of Arkansas at Little Rock (US)
1 shared publication
- Encapsulation of Inositol Hexakisphosphate with Chitosan via Gelation to Facilitate Cellular Delivery and Programmed Cell Death in Human Breast Cancer Cells
Bijay P. Chhetri
University of Arkansas at Little Rock
1 shared publication
In database
- Encapsulation of Inositol Hexakisphosphate with Chitosan via Gelation to Facilitate Cellular Delivery and Programmed Cell Death in Human Breast Cancer Cells
Similar Researchers
Based on overlapping research topics
Filipa Ponte
University of Arkansas for Medical Sciences
Bone Metabolism and Diseases
Aging and Longevity in Model Organisms
Mitochondrial Function and Pathology
Wen Ling
University of Arkansas for Medical Sciences
Bone Metabolism and Diseases
Cancer-related molecular mechanisms research
Mitochondrial Function and Pathology
Aaron Warren
University of Arkansas for Medical Sciences
Bone Metabolism and Diseases
Aging and Longevity in Model Organisms
Mitochondrial Function and Pathology
Maria Almeida
University of Arkansas for Medical Sciences
Bone Metabolism and Diseases
Aging and Longevity in Model Organisms
Mitochondrial Function and Pathology
Jinhu Xiong
University of Arkansas for Medical Sciences
Bone Metabolism and Diseases
Aging and Longevity in Model Organisms
Mitochondrial Function and Pathology
Nukhet Aykin-Burns
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
Mitochondrial Function and Pathology
Cellular transport and secretion